EM Field and Biological Systems Interactions

Research of interactions between em fleld and biological systems is of growing interests elsewhere. Also here in czech republic there are several groups working in this fleld, often in international co-operations. We will describe here mainly basic technical equipment developed for 5 difierent research projects in the discussed area of interactions of em fleld and biological systems. 1. INTRODUCTION In present time four research institutions here in the Czech Republic run research projects focused on studies of interactions between EM fleld and biological systems. These institutions are technically supported by Dept. of EM Field of the Czech Technical University in Prague. In this contribution we would like to give more details about that projects and obtained technical results (i.e., description of developed exposition systems). Three of discussed projects (1 in Germany and 2 here in Czech Republic) are basic research for simulation of the microwave hyperthermia treatment. Other two projects (both in Czech Republic are focused on simulation of the case of exposition by mobile phone. In the modern view, cancer is intended as a complex illness, involving the cells that undergo to transformation, their environment, and the general responses at biochemical and biological levels induced in the host. Consequently, the anti-cancer btreatment protocols need to be multi-modal to reach curative efiects. Especially after the technical improvements achieved in the last 15 years by bio-medical engineering, microscopy devices, and molecular biology methods, the combinations of therapeutic procedures are growing in interest in basic and clinical research. The combination of applied biological research together to the physical sciences can ofier im- portant perspectives in anticancer therapy (e.g., difierent methodologies and technical devices for application of energies to pathological tissues). The modern bioengineering knowledge applied to traditional tools, as the microscopy, has largely renewed and expanded the flelds of their applications (e.g.,: in vivo imaging), pushing the interest for direct morpho-functional investigations of the biomedical problems. 2. WAVEGUIDE APPLICATOR

[1]  Jan Vrba,et al.  Medical Applications of Microwaves , 2004, Other Conferences.

[2]  J. Vrba,et al.  Evanescent-mode applicators (EMA) for superficial and subcutaneous hyperthermia , 1993, IEEE Transactions on Biomedical Engineering.