Short communication Single-cell models: promise and limitations

This article describes the development of single-cell models, their uses and accomplishments, the barriers to the greater adoption, and a perspective on challenges to the biochemical engineering community where the single-cell model approach may be used advantageously. In particular, it may become an important tool in relating genomic information to cellular regulation and dynamics. © 1999 Elsevier Science B.V. All rights reserved.

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