Direct HPLC enantioseparation of omeprazole and its chiral impurities: application to the determination of enantiomeric purity of esomeprazole magnesium trihydrate.

[1]  S. Fiore,et al.  Semipreparative HPLC enantioseparation, chiroptical properties, and absolute configuration of two novel cyclooxygenase-2 inhibitors. , 2010, Chirality.

[2]  R. Cirilli,et al.  Development and validation of an enantioselective and chemoselective HPLC method using a Chiralpak IA column to simultaneously quantify (R)-(+)- and (S)-(-)-lansoprazole enantiomers and related impurities. , 2009, Journal of pharmaceutical and biomedical analysis.

[3]  R. Cirilli,et al.  Direct high-performance liquid chromatography enantioseparation of terazosin on an immobilised polysaccharide-based chiral stationary phase under polar organic and reversed-phase conditions. , 2009, Journal of chromatography. A.

[4]  A. Mai,et al.  Chiral HPLC separation and absolute configuration of novel S-DABO derivatives. , 2009, Chirality.

[5]  Tong Zhang,et al.  Common approaches for efficient method development with immobilised polysaccharide-derived chiral stationary phases. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[6]  C. Villani,et al.  HPLC enantioseparation and absolute configuration of novel anti-inflammatory pyrrole derivatives. , 2008, Chirality.

[7]  R. Cirilli,et al.  High-performance liquid chromatography enantioseparation of proton pump inhibitors using the immobilized amylose-based Chiralpak IA chiral stationary phase in normal-phase, polar organic and reversed-phase conditions. , 2008, Journal of chromatography. A.

[8]  R. Nageswara Rao,et al.  Enantiospecific resolution of rabeprazole by liquid chromatography on amylose-derived chiral stationary phase using photo diode array and polarimetric detectors in series. , 2006, Talanta.

[9]  P. Patil,et al.  Development of safer molecules through chirality. , 2006, Indian journal of medical sciences.

[10]  N. Yasui-Furukori,et al.  Enantioselective disposition of rabeprazole in relation to CYP2C19 genotypes. , 2006, British journal of clinical pharmacology.

[11]  D. Secci,et al.  Analytical and semipreparative high performance liquid chromatography enantioseparation of new substituted 1-thiocarbamoyl-3,5-diaryl-4,5-dihydro-(1H)-pyrazoles on polysaccharide-based chiral stationary phases in normal-phase, polar organic and reversed-phase conditions. , 2006, Journal of chromatography. A.

[12]  M. D. del Nozal,et al.  Comparative study of the enantioselective separation of several antiulcer drugs by high-performance liquid chromatography and supercritical fluid chromatography. , 2005, Journal of chromatography. A.

[13]  Tong Zhang,et al.  Optimization of the chiral separation of a Ca-sensitizing drug on an immobilized polysaccharide-based chiral stationary phase: case study with a preparative perspective. , 2005, Journal of chromatography. A.

[14]  M. Tsujii,et al.  Microbial synthesis of a proton pump inhibitor by enantioselective oxidation of a sulfide into its corresponding sulfoxide by Cunninghamella echinulata MK40 , 2001, Biotechnology Letters.

[15]  T. Andersson Single-Isomer Drugs , 2004, Clinical pharmacokinetics.

[16]  Per Lindberg,et al.  A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole , 2003, Nature Reviews Drug Discovery.

[17]  J. Caldwell,et al.  Putting chirality to work: the strategy of chiral switches , 2002, Nature Reviews Drug Discovery.

[18]  P. Kale-Pradhan,et al.  Esomeprazole for Acid Peptic Disorders , 2002, The Annals of pharmacotherapy.

[19]  P. Lagerström,et al.  Determination of the enantiomers of omeprazole in blood plasma by normal-phase liquid chromatography and detection by atmospheric pressure ionization tandem mass spectrometry. , 1999, Journal of chromatography. B, Biomedical sciences and applications.

[20]  P. Lagerström,et al.  Stereoselective effects in the separation of enantiomers of omeprazole and other substituted benzimidazoles on different chiral stationary phases , 1994 .

[21]  P. Lindberg,et al.  Resolution of the enantiomers of omeprazole and some of its analogues by liquid chromatography on a trisphenylcarbamoylcellulose-based stationary phase. The effect of the enantiomers of omeprazole on gastric glands. , 1990, Journal of chromatography.

[22]  H. Borén,et al.  Direct optical resolution of a series of pharmacologically active racemic sulfoxides by high-performance liquid affinity chromatography. , 1984, Analytical biochemistry.