Review on CFD simulation in heart with dilated cardiomyopathy and myocardial infarction

The heart is a sophisticated functional organ that plays a crucial role in the blood circulatory system. Hemodynamics within the heart chamber can be indicative of exert cardiac health. Due to the limitations of current cardiac imaging modalities, computational fluid dynamics (CFD) have been widely used for the purposes of cardiac function assessment and heart disease diagnosis, as they provide detailed insights into the cardiac flow field. An understanding of ventricular hemodynamics and pathological severities can be gained through studies that employ the CFD method. In this research the hemodynamics of two common myocardial diseases, dilated cardiomyopathy (DCM) and myocardial infarction (MI) were investigated, during both the filling phase and the whole cardiac cycle, through a prescribed geometry and fluid structure interaction (FSI) approach. The results of the research indicated that early stage disease identification and the improvement of cardiac assisting devices and therapeutic procedures can be facilitated through the use of the CFD method.

[1]  S. Yusuf,et al.  Cardiac mechanics during development of heart failure. SOLVD Investigators. , 1993, Circulation.

[2]  Jacques Melin,et al.  Cardiac Mechanics During Development of Heart-failure , 1993 .

[3]  Toshiaki Hisada,et al.  Finite Element Analysis of Ventricular Wall Motion and Intra-Ventricular Blood Flow in Heart with Myocardial Infarction , 2004 .

[4]  D. Mann,et al.  Mechanisms and models in heart failure: A combinatorial approach. , 1999, Circulation.

[5]  A D Augst,et al.  Accuracy and reproducibility of CFD predicted wall shear stress using 3D ultrasound images. , 2003, Journal of biomechanical engineering.

[6]  Richard Wheeler,et al.  The role of echocardiography in guiding management in dilated cardiomyopathy. , 2009, European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology.

[7]  J. V. NIXON,et al.  Estimation of Myocardial Involvement in Patients with Acute Myocardial Infarction by Two‐dimensional Echocardiography , 1980, Circulation.

[8]  M B Visscher,et al.  The regulation of the energy output of the heart , 1927, The Journal of physiology.

[9]  A. Quarteroni,et al.  Navier-Stokes/Darcy Coupling: Modeling, Analysis, and Numerical Approximation , 2009 .

[10]  A. D. Gosman,et al.  Computational Flow Modeling of the Left Ventricle Based on In Vivo MRI Data: Initial Experience , 2001, Annals of Biomedical Engineering.

[11]  C. R. Ethier,et al.  Hemodynamics in the mouse aortic arch as assessed by MRI, ultrasound, and numerical modeling. , 2007, American journal of physiology. Heart and circulatory physiology.

[12]  William J van Gaal Dr,et al.  Platypnea-orthodeoxia associated with a fenestrated atrial septal aneurysm: Case Report , 2005 .

[13]  Charles Taylor,et al.  EXPERIMENTAL AND COMPUTATIONAL METHODS IN CARDIOVASCULAR FLUID MECHANICS , 2004 .

[14]  Liang Ge,et al.  The use of computational flow modeling (CFD) to determine the effect of left ventricular shape on blood flow in the left ventricle. , 2009, The Annals of thoracic surgery.

[15]  David A Bluemke,et al.  Regional myocardial function: advances in MR imaging and analysis. , 2003, Radiographics : a review publication of the Radiological Society of North America, Inc.

[16]  A. L. Morse,et al.  Magnetic Recordings of the Heart's Electrical Activity with a Cryogenic Magnetometer , 1971 .

[17]  Erwan Donal,et al.  Mitral regurgitation in dilated cardiomyopathy: value of both regional left ventricular contractility and dyssynchrony. , 2009, European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology.

[18]  D. Burkhoff,et al.  Diastolic dysfunction: can it be diagnosed by Doppler echocardiography? , 2004, Journal of the American College of Cardiology.

[19]  P. Verdonck,et al.  Computer simulation of intraventricular flow and pressure gradients during diastole. , 2000, Journal of biomechanical engineering.

[20]  Herbert Oertel,et al.  The Karlsruhe Heart Model KaHMo: A modular framework for numerical simulation of cardiac hemodynamics , 2009 .

[21]  H. Imai,et al.  [Left ventricular trabeculae evaluated with MRI in dilated cardiomyopathy and old myocardial infarction]. , 1992, Journal of cardiology.

[22]  Alison L Marsden,et al.  Recent advances in the application of computational mechanics to the diagnosis and treatment of cardiovascular disease. , 2009, Revista espanola de cardiologia.

[23]  T. Böhlke,et al.  Partitioned Fluid–Solid Coupling for Cardiovascular Blood Flow , 2010, Annals of Biomedical Engineering.

[24]  Toshiaki Hisada,et al.  Multiphysics simulation of left ventricular filling dynamics using fluid-structure interaction finite element method. , 2004, Biophysical journal.

[25]  E BERGLUND,et al.  Ventricular Function: I. Starling's Law of the Heart Studied by Means of Simultaneous Right and Left Ventricular Function Curves in the Dog , 1954, Circulation.

[26]  P. Libby,et al.  Braunwald's heart disease , 2015 .

[27]  E. Starling,et al.  The regulation of the heart beat , 1914, The Journal of physiology.

[28]  A M Shutov,et al.  Does E/A ratio correctly estimate diastolic dysfunction in patients with chronic renal failure? , 2000, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

[29]  E. Starling,et al.  On the mechanical factors which determine the output of the ventricles , 1914, The Journal of physiology.

[30]  Charles A. Taylor,et al.  Patient-specific modeling of cardiovascular mechanics. , 2009, Annual review of biomedical engineering.

[31]  Jürgen Hennig,et al.  Fluid-dynamic modeling of the human left ventricle: methodology and application to surgical ventricular reconstruction. , 2009, The Annals of thoracic surgery.

[32]  Karl Swedberg,et al.  Influence of Ejection Fraction on Cardiovascular Outcomes in a Broad Spectrum of Heart Failure Patients , 2005, Circulation.

[33]  Tohru Masuyama,et al.  Diastolic Dysfunction and Diastolic Heart Failure , 2000 .

[34]  Douglas L. Mann,et al.  Comprar Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 2-Volume Set, 9th Edition Expert Consult Premium Edition €“ Enhanced Online Features | Peter Libby | 9781437727081 | Saunders , 2011 .

[35]  D. Ramsdale,et al.  An echocardiographic assessment of cardiac morphology and common ECG findings in teenage professional soccer players: reference ranges for use in screening , 2001, Heart.

[36]  Zoran B Popović,et al.  Assessment of left ventricular function by cardiac ultrasound. , 2006, Journal of the American College of Cardiology.

[37]  Michael R. Zile,et al.  Contractile Behavior of the Left Ventricle in Diastolic Heart Failure: With Emphasis on Regional Systolic Function , 2006 .

[38]  M T McNamara,et al.  Acute myocardial infarction: MR evaluation in 29 patients. , 1987, AJR. American journal of roentgenology.

[39]  Gianni Pedrizzetti,et al.  Fluid dynamics of the left ventricular filling in dilated cardiomyopathy. , 2002, Journal of biomechanics.

[40]  S. Wilansky,et al.  Echocardiography in the assessment of complications of myocardial infarction. , 1991, Texas Heart Institute journal.

[41]  A de Roos,et al.  MR imaging of acute myocardial infarction: value of Gd-DTPA. , 1988, AJR. American journal of roentgenology.

[42]  M. Nieminen,et al.  Echoventriculographic detection, localization, and quantification of left ventricular asynergy in acute myocardial infarction. A correlative echo- and electrocardiographic study. , 1975, British heart journal.

[43]  Gianni Pedrizzetti,et al.  Three-dimensional filling flow into a model left ventricle , 2005, Journal of Fluid Mechanics.

[44]  J. Shillingford,et al.  Hemodynamic Changes in Patients with Acute: Myocardial Infarction , 1965, Circulation.

[45]  Bart Bijnens,et al.  Failure to Unmask Pseudonormal Diastolic Function by a Valsalva Maneuver: Tricuspid Insufficiency Is a Major Factor , 2011, Circulation. Cardiovascular imaging.

[46]  A P Yoganathan,et al.  Three-dimensional computational model of left heart diastolic function with fluid-structure interaction. , 2000, Journal of biomechanical engineering.

[47]  Sven Eriksson,et al.  Heart failure after myocardial infarction: the importance of diastolic dysfunction. A prospective clinical and echocardiographic study. , 1995, European heart journal.

[48]  Maria I Altbach,et al.  Cardiac MRI is Complementary to Echocardiography in the Assessment of Cardiac Masses , 2007, Echocardiography.

[49]  P. Hunter,et al.  Fluid–solid coupling for the investigation of diastolic and systolic human left ventricular function , 2011 .

[50]  Gianni Pedrizzetti,et al.  Intraventricular vortex flow changes in the infarcted left ventricle: numerical results in an idealised 3D shape , 2011, Computer methods in biomechanics and biomedical engineering.

[51]  Maurizio Galderisi,et al.  Diastolic dysfunction and diastolic heart failure: diagnostic, prognostic and therapeutic aspects , 2005, Cardiovascular ultrasound.

[52]  Ismail Celik,et al.  CFD mesh generation for biological flows: Geometry reconstruction using diagnostic images , 2009 .

[53]  Michael Markl,et al.  MRI-Based CFD Analysis of Flow in a Human Left Ventricle: Methodology and Application to a Healthy Heart , 2009, Annals of Biomedical Engineering.

[54]  Hervé Delingette,et al.  Simulation of cardiac pathologies using an electromechanical biventricular model and XMR interventional imaging , 2005, Medical Image Anal..

[55]  S-W Lee,et al.  Lee systemic lupus erythematosus E / E ' ratio is more sensitive than E / A ratio for detection of left ventricular diastolic dysfunction in , 2008 .

[56]  Eberhard Kuon,et al.  Doppler Echocardiography in Dilated Cardiomyopathy: Diastolic and Combined Systolic/Diastolic Parameters Offer More Detailed Information on Left Ventricular Global Dysfunction than Systolic Parameters , 2002 .

[57]  Tatsuo Kumazaki,et al.  MRI of cardiac morphology and function after percutaneous transluminal septal myocardial ablation for hypertrophic obstructive cardiomyopathy. , 2004, AJR. American journal of roentgenology.

[58]  Y Nimura,et al.  Abnormal blood pathways in left ventricular cavity in acute myocardial infarction. Experimental observations with special reference to regional wall motion abnormality and hemostasis. , 1988, Circulation.

[59]  Roberto M Lang,et al.  Insights into myocardial mechanics in normal and pathologic states using newer echocardiographic techniques , 2008, Current heart failure reports.

[60]  Robert C Gorman,et al.  Extension of borderzone myocardium in postinfarction dilated cardiomyopathy. , 2002, Journal of the American College of Cardiology.

[61]  A J Tajik,et al.  Two-Dimensional and Doppler Echocardiography Alone Can Adequately Define Preoperative Anatomy and Hemodynamic Status before Repair of Complete Atrioventricular Septal Defect in Infants <1 Year Old , 1994, Circulation.

[62]  U Sechtem,et al.  Chronic myocardial infarction: assessment of morphology, function, and perfusion by gradient echo magnetic resonance imaging and 99mTc-methoxyisobutyl-isonitrile SPECT. , 1992, American heart journal.

[63]  H. Oertel,et al.  Fluid-Structure Coupled CFD Simulation of the Left Ventricular Flow During Filling Phase , 2005, Annals of Biomedical Engineering.

[64]  A. Bolger,et al.  Passing strange: flow in the failing ventricle. , 2010, Circulation. Heart failure.

[65]  R. Doughty,et al.  Pseudonormal mitral filling is associated with similarly poor prognosis as restrictive filling in patients with heart failure and coronary heart disease: a systematic review and meta-analysis of prospective studies. , 2009, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography.

[66]  K.V.L. Narayana,et al.  Wavelet based QRS detection in ECG using MATLAB , 2011 .

[67]  D N Firmin,et al.  Subject-specific computational simulation of left ventricular flow based on magnetic resonance imaging , 2008, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[68]  F. N. van de Vosse,et al.  Influence of dilated cardiomyopathy and a left ventricular assist device on vortex dynamics in the left ventricle , 2008, Computer methods in biomechanics and biomedical engineering.

[69]  C. Peskin,et al.  A three-dimensional computational method for blood flow in the heart. 1. Immersed elastic fibers in a viscous incompressible fluid , 1989 .

[70]  A. A. Young,et al.  Magnetic resonance imaging and ventricle mechanics , 2001, Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.