Polymorphisms of CYP2D6 gene and gefitinib-induced hepatotoxicity.
暂无分享,去创建一个
S. Nonen | Y. Fujio | J. Azuma | T. Kijima | J. Uchida | A. Kumanogoh | F. Imamura | S. Yokota | S. Minami | K. Komuta | T. Takimoto | Yasushi Otani | Y. Namba | M. Mori | M. Furukawa | N. Tsuruta | I. Tachibana
[1] Jun Ma,et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. , 2011, The Lancet. Oncology.
[2] S. Nonen,et al. Safe and successful treatment with erlotinib after gefitinib-induced hepatotoxicity: difference in metabolism as a possible mechanism. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[3] L. Tanoue. Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR , 2011 .
[4] M. Fukuoka,et al. Successful treatment with erlotinib after gefitinib-related severe hepatotoxicity. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[5] D. Hochstrasser,et al. Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety , 2010, British journal of pharmacology.
[6] S. Toyooka,et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. , 2010, The Lancet. Oncology.
[7] L. Tanoue,et al. Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma , 2010 .
[8] Lin Huan,et al. Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer , 2010 .
[9] D. Hochstrasser,et al. Genetic polymorphisms and drug interactions modulating CYP 2 D 6 and CYP 3 A activities have a major effect on oxycodone analgesic efficacy and safetybph , 2010 .
[10] R. Andrade,et al. Pharmacogenomics in drug induced liver injury. , 2009, Current drug metabolism.
[11] M. Cameron,et al. Bioactivation of the epidermal growth factor receptor inhibitor gefitinib: implications for pulmonary and hepatic toxicities. , 2009, Chemical research in toxicology.
[12] N. Rizzo-Padoin,et al. Gefitinib-phenytoin interaction is not correlated with the C-erythromycin breath test in healthy male volunteers. , 2009, British journal of clinical pharmacology.
[13] S. Zhan,et al. Drug-metabolising enzyme polymorphisms and predisposition to anti-tuberculosis drug-induced liver injury: a meta-analysis. , 2008, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.
[14] Shufeng Zhou,et al. Clinically Important Drug Interactions Potentially Involving Mechanism-based Inhibition of Cytochrome P450 3A4 and the Role of Therapeutic Drug Monitoring , 2007, Therapeutic drug monitoring.
[15] M. Hidalgo,et al. Differential Metabolism of Gefitinib and Erlotinib by Human Cytochrome P450 Enzymes , 2007, Clinical Cancer Research.
[16] Manuel Hidalgo,et al. CYP3A phenotyping approach to predict systemic exposure to EGFR tyrosine kinase inhibitors. , 2006, Journal of the National Cancer Institute.
[17] K. Uematsu,et al. Promising new treatment schedule for gefitinib responders after severe hepatotoxicity with daily administration. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[18] H. Swaisland,et al. Exploring the Relationship Between Expression of Cytochrome P450 Enzymes and Gefitinib Pharmacokinetics , 2006, Clinical pharmacokinetics.
[19] David A. Flockhart,et al. CYP2D6 genotype, antidepressant use, and tamoxifen metabolism during adjuvant breast cancer treatment. , 2005, Journal of the National Cancer Institute.
[20] G. S. Miles,et al. Cytochrome P450-dependent metabolism of gefitinib , 2005, Xenobiotica; the fate of foreign compounds in biological systems.
[21] J. Azuma,et al. The frequency of candidate alleles for CYP2D6 genotyping in the Japanese population with an additional respect to the -1584C to G substitution. , 2005, Drug metabolism and pharmacokinetics.
[22] M. Ranson,et al. Pharmacokinetic Drug Interactions of Gefitinib with Rifampicin, Itraconazole and Metoprolol , 2005, Clinical pharmacokinetics.
[23] Y. Daali,et al. Codeine intoxication associated with ultrarapid CYP2D6 metabolism. , 2004, The New England journal of medicine.
[24] Julie A. Johnson,et al. Differences in Drug Pharmacokinetics Between East Asians and Caucasians and the Role of Genetic Polymorphisms , 2004, Journal of clinical pharmacology.
[25] S. Steinberg,et al. Evaluation of biologic end points and pharmacokinetics in patients with metastatic breast cancer after treatment with erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[26] K. Tanikawa,et al. Association of troglitazone-induced liver injury with mutation of the cytochrome P450 2C19 gene. , 2003, Hepatology research : the official journal of the Japan Society of Hepatology.
[27] Masahiro Fukuoka,et al. Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer (The IDEAL 1 Trial) [corrected]. , 2003, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[28] M. Kitada. Genetic polymorphism of cytochrome P450 enzymes in Asian populations: focus on CYP2D6. , 2003, International journal of clinical pharmacology research.
[29] Bradford Ld. CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. , 2002 .
[30] J. Azuma,et al. CYP2D6 genotypes in a Japanese population: low frequencies of CYP2D6 gene duplication but high frequency of CYP2D6*10. , 2000, Pharmacogenetics.
[31] M. Ingelman-Sundberg,et al. PCR-based genotyping for duplicated and deleted CYP2D6 genes. , 1996, Pharmacogenetics.
[32] W. M. Lee,et al. Drug-induced hepatotoxicity. , 1995, The New England journal of medicine.
[33] O. Andreassen,et al. Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology. , 1995, Pharmacogenetics.
[34] S. Sherlock,et al. Impaired oxidation of debrisoquine in patients with perhexiline liver injury. , 1984, Gut.
[35] M. Hidalgo,et al. CYP 3 A Phenotyping Approach to Predict Systemic Exposure to EGFR Tyrosine Kinase Inhibitors , 2022 .