Ellipsometer Recordings of Changes in Optical Thickness of Adsorbed Films associated with Surface Activation of Blood Clotting

RECENT publications1–4 indicate that when blood comes into contact with glass, Factor XII is adsorbed and in turn adsorbs Factor XI. Much of the resulting ‘activation product’ can be recovered from, the adsorbing surface1,3, but other indirect evidence shows that measurable amounts are released4–7.