A selective radiobrominated cocaine analogue for imaging of dopamine uptake sites: pharmacological evaluation and PET experiments.

[1]  D. Guilloteau,et al.  Exploration of the dopamine transporter: in vitro and in vivo characterization of a high-affinity and high-specificity iodinated tropane derivative (E)-N-(3-iodoprop-2-enyl)-2beta-carbomethoxy-3beta-(4'-m ethylph enyl)nortropane (PE2I). , 1998, Nuclear medicine and biology.

[2]  D. Guilloteau,et al.  Synthesis of iodinated and radioiodinated (E)-N-(3-iodoprop-2-enyl)-2β-carbomethoxy-3β-(3',4'-dichlorophenyl) nortropane (β-CDIT) : A ligand for the dopamine transporter , 1997 .

[3]  Douglas W. Jones,et al.  Analysis of the metabolites of [I‐123]β‐CIT in plasma of human and nonhuman primates , 1997, Synapse.

[4]  P B Hoffer,et al.  Microdialysis and SPECT measurements of amphetamine‐induced dopamine release in nonhuman primates , 1997, Synapse.

[5]  F. Dollé,et al.  Synthesis of a potential M1 muscarinic agent [76Br]bromocaramiphen , 1996 .

[6]  Christer Halldin,et al.  [11C]β‐CIT‐FE, a radioligand for quantitation of the dopamine transporter in the living brain using positron emission tomography , 1996 .

[7]  H. Kung,et al.  Striatal dopamine transporter imaging in nonhuman primates with iodine-123-IPT SPECT. , 1995, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[8]  K. Någren,et al.  PET examination of the monoamine transporter with [11c]β‐CIT and [11c]β‐CFT in early parkinson's disease , 1995 .

[9]  C. Halldin,et al.  [O-methyl-11C]beta-CIT-FP, a potential radioligand for quantitation of the dopamine transporter: preparation, autoradiography, metabolite studies, and positron emission tomography examinations. , 1995, Nuclear medicine and biology.

[10]  J. Tiihonen,et al.  Lipophilic metabolite of [123I]β‐CIT in human plasma may obstruct quantitation of the dopamine transporter , 1995, Synapse.

[11]  C. Halldin,et al.  Synthesis of 2β‐carbomethoxy‐3β‐(4‐[76Br]bromophenyl)tropane ([76Br]β‐CBT), a pet tracer for in vivo imaging of the dopamine uptake sites , 1995 .

[12]  H. Kung,et al.  Synthesis and characterization of radioiodinated N-(3-iodopropen-1-yl)-2 beta-carbomethoxy-3 beta-(4-chlorophenyl)tropanes: potential dopamine reuptake site imaging agents. , 1994, Journal of medicinal chemistry.

[13]  C. Halldin,et al.  [11C] beta-CIT, a cocaine analogue. Preparation, autoradiography and preliminary PET investigations. , 1993, Nuclear medicine and biology.

[14]  Marc Laruelle,et al.  SPECT imaging of dopamine and serotonin transporters with [123I]β‐CIT: Pharmacological characterization of brain uptake in nonhuman primates , 1993, Synapse.

[15]  F I Carroll,et al.  High‐affinity binding of [125I]RTI‐55 to dopamine and serotonin transporters in rat brain , 1992, Synapse.

[16]  M. Kuhar,et al.  [123/125I]RTI‐55, an in vivo label for the serotonin transporter , 1992, Synapse.

[17]  N. Volkow,et al.  Quantitative autoradiography of cocaine binding sites in human brain postmortem , 1992, Synapse.

[18]  P B Hoffer,et al.  [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane: high-affinity SPECT radiotracer of monoamine reuptake sites in brain. , 1991, Journal of medicinal chemistry.

[19]  M. Kuhar,et al.  [125I]RTI-55: a potent ligand for dopamine transporters. , 1991, European journal of pharmacology.

[20]  Victor W. Pike,et al.  Radiopharmaceuticals for Positron Emission Tomography , 1993, Developments in Nuclear Medicine.

[21]  S. Moerlein,et al.  Effect of lipophilicity on the in vivo localization of radiolabelled spiperone analogues. , 1985, International journal of nuclear medicine and biology.