Exchange K-nailing, Augmented Plating Technique for Atypical Femur Diaphyseal Non-union, and Implant Failure – A Case Report

Introduction: Atypical femoral fractures (AFFs) have an unpredictable healing process leading to higher complication rates. The literature describes various treatment modalities of non-unions in AFF. We aimed to report a case of non-union with AFF and successful union with exchange K-nailing and augmented plating techniques. Case Report: A 75-year-old lady with 5 years of bisphosphonate intake sustained an AFF at the mid-diaphyseal level after a trivial injury which was fixed with closed intramedullary nailing. Nine months after fixation, she developed refracture at the fracture site with segmental breakage of the nail suggesting non-union. This was managed by the removal of fibrous structures at the fracture site, removal of a broken nail, exchange K-nailing, augmented plating, and iliac crest bone grafting. The fracture healed at 15 months from the injury and achieved good functional outcome at a short-term follow-up of 1 year. Conclusion: Our case report highlights the challenges of treating diaphyseal AFF and the combined benefit of exchange nailing and augmented plating with bone grafting in treating AFFs with non-union.

[1]  C. Pradhan,et al.  Intramedullary Nailing: Definitive as well as Prophylactic Fixation Method in a Case of Bilateral Atypical Femoral Fractures – A Case Report , 2019, Journal of orthopaedic case reports.

[2]  B. Min,et al.  Incidence, risk factors, and fracture healing of atypical femoral fractures: a multicenter case-control study , 2018, Osteoporosis International.

[3]  A. Pispati,et al.  Oral Bisphosphonate Induced Recurrent Osteonecrosis of Jaw with Atypical Femoral Fracture and Subsequent Mandible Fracture in the Same Patient: A Case Report , 2018, Journal of orthopaedic case reports.

[4]  L. Chen,et al.  Surgical outcome of atypical subtrochanteric and femoral fracture related to bisphosphonates use in osteoporotic patients with or without teriparatide treatment , 2017, BMC Musculoskeletal Disorders.

[5]  Chetan Puram,et al.  Effectiveness of exchange K-nail and augmented plating in aseptic femoral diaphyseal non-union. , 2017, Injury.

[6]  A. Lovy,et al.  Intramedullary Nail Fixation of Atypical Femur Fractures With Bone Marrow Aspirate Concentrate Leads to Faster Union: A Case-Control Study. , 2017, Journal of orthopaedic trauma.

[7]  R. Kuroda,et al.  Clinical Experience With the Use of Low-Intensity Pulsed Ultrasound (LIPUS) in the Treatment of Atypical Femoral Fractures , 2017, Journal of orthopaedic trauma.

[8]  P. Giannoudis,et al.  Atypical femoral fractures related to bisphosphonate treatment: ISSUES AND CONTROVERSIES RELATED TO THEIR SURGICAL MANAGEMENT , 2017, The bone & joint journal.

[9]  Seung-Jae Lim,et al.  Factors Associated with Increased Healing Time in Complete Femoral Fractures After Long-Term Bisphosphonate Therapy. , 2016, The Journal of bone and joint surgery. American volume.

[10]  Z. Rosenberg,et al.  Healing Delayed But Generally Reliable After Bisphosphonate-associated Complete Femur Fractures Treated with IM Nails , 2014, Clinical orthopaedics and related research.

[11]  P. Syson,et al.  Construct Failure in an Atypical Femoral Fracture treated with Intramedullary Nailing: A Case Report , 2014, Malaysian orthopaedic journal.

[12]  Thomas D Brown,et al.  Atypical Subtrochanteric and Diaphyseal Femoral Fractures: Second Report of a Task Force of the American Society for Bone and Mineral Research , 2011, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[13]  S. Giannotti,et al.  Pseudoarthrosis in atypical femoral fracture: case report , 2013, Osteoporosis International.

[14]  J. Lane,et al.  Bisphosphonate therapy and atypical fractures. , 2013, The Orthopedic clinics of North America.

[15]  A. Negri,et al.  Healing of subtrochanteric atypical fractures after strontium ranelate treatment. , 2012, Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases.

[16]  J. Watson,et al.  Treatment of femoral fracture nonunion after long-term bisphosphonate use. , 2012, Orthopedics.

[17]  F. Bandeira,et al.  Atypical femoral fractures during prolonged use of bisphosphonates: short-term responses to strontium ranelate and teriparatide. , 2011, The Journal of clinical endocrinology and metabolism.

[18]  M. Liebergall,et al.  The outcome of surgically treated femur fractures associated with long-term bisphosphonate use. , 2011, The Journal of trauma.

[19]  Y. S. Choi,et al.  Comparison of mechanical rigidity between plate augmentation leaving the nail in situ and interlocking nail using cadaveric fracture model of the femur , 2011, International Orthopaedics.

[20]  M. McDonald,et al.  Bisphosphonate treatment and fracture repair , 2007 .