A molecular model of a point mutation (Val297Met) in the serine protease domain of protein C

[1]  J. Emmerich,et al.  Protein C and protein S deficiencies. , 1997, Seminars in hematology.

[2]  P. Reitsma.  Protein C Deficiency: from Gene Defects to Disease , 1997, Thrombosis and Haemostasis.

[3]  S Foundling,et al.  The 2.8 A crystal structure of Gla‐domainless activated protein C. , 1996, The EMBO journal.

[4]  D. Cooper,et al.  Molecular reconstruction and homology modelling of the catalytic domain of the common ancestor of the haemostatic vitamin-K-dependent serine proteinases , 1996, Human Genetics.

[5]  M. Alessi,et al.  Purpura Fulminans in a Patient Homozygous for a Mutation in the Protein C Gene - Prenatal Diagnosis in a Subsequent Pregnancy , 1996, Thrombosis and Haemostasis.

[6]  T. Miyata,et al.  Protein C Osaka 10 with Aberrant Propeptide Processing: Loss of Anticoagulant Activity Due to an Amino Acid Substitution in the Protein C Precursor , 1995, Thrombosis and Haemostasis.

[7]  T. Miyata,et al.  Six missense mutations associated with type I and type II protein C deficiency and implications obtained from molecular modelling , 1994, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

[8]  N. Tsushima,et al.  Three Missense Mutations in the Protein C Heavy Chain Causing Type I and Type II Protein C Deficiency , 1994, Thrombosis and Haemostasis.

[9]  A. Wacey,et al.  A molecular model of the serine protease domain of activated protein C: application to the study of missense mutations causing protein C deficiency , 1993, British journal of haematology.

[10]  P. Reitsma,et al.  The spectrum of genetic defects in a panel of 40 Dutch families with symptomatic protein C deficiency type I: heterogeneity and founder effects. , 1991, Blood.

[11]  G. Crabtree,et al.  Evolution and organization of the human protein C gene. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[12]  G. Crabtree,et al.  The structure and evolution of a 461 amino acid human protein C precursor and its messenger RNA, based upon the DNA sequence of cloned human liver cDNAs. , 1985, Nucleic acids research.

[13]  E. Davie,et al.  The nucleotide sequence of the gene for human protein C. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[14]  E. Davie,et al.  Characterization of a cDNA coding for human protein C. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[15]  J. Griffin,et al.  Deficiency of protein C in congenital thrombotic disease. , 1981, The Journal of clinical investigation.

[16]  W. Kisiel,et al.  Proteolytic activation of protein C from bovine plasma. , 1976, Biochemistry.