Regulation of ferritin genes and protein.

Increasingly, perturbations in cellular iron and ferritin are emerging as an important element in the pathogenesis of disease. These changes in ferritin are important not only in the classic diseases of iron acquisition, transport, and storage, such as primary hemochromatosis, but also in diseases

[1]  J. Koziol,et al.  Reference centiles for serum ferritin and percentage of transferrin saturation, with application to mutations of the HFE gene. , 2001, Clinical chemistry.

[2]  M. Karin,et al.  Signal transduction by tumor necrosis factor and its relatives. , 2001, Trends in cell biology.

[3]  V. Belegu,et al.  Specific repression of β-globin promoter activity by nuclear ferritin , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[4]  J. Graziano,et al.  Regulation of the 75-kDa Subunit of Mitochondrial Complex I by Iron* , 2001, The Journal of Biological Chemistry.

[5]  P. Arosio,et al.  A Human Mitochondrial Ferritin Encoded by an Intronless Gene* , 2001, The Journal of Biological Chemistry.

[6]  C. Morris,et al.  Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease , 2001, Nature Genetics.

[7]  F. Torti,et al.  Ferritin and the response to oxidative stress. , 2001, Biochemical Journal.

[8]  K Takada,et al.  A mutation, in the iron-responsive element of H ferritin mRNA, causing autosomal dominant iron overload. , 2001, American journal of human genetics.

[9]  Y. Gruenbaum,et al.  Repression of the heavy ferritin chain increases the labile iron pool of human K562 cells. , 2001, The Biochemical journal.

[10]  M. Ferrari,et al.  Double-gradient denaturing gradient gel electrophoresis assay for identification of L-ferritin iron-responsive element mutations responsible for hereditary hyperferritinemia-cataract syndrome: identification of the new mutation C14G. , 2001, Clinical chemistry.

[11]  J. Briat,et al.  Characterization of an Iron-dependent Regulatory Sequence Involved in the Transcriptional Control of AtFer1and ZmFer1 Plant Ferritin Genes by Iron* , 2001, The Journal of Biological Chemistry.

[12]  Kazuhiro Iwai,et al.  Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice , 2001, Nature Genetics.

[13]  M. Suzuki,et al.  Effects of hyperoxia and iron on iron regulatory protein-1 activity and the ferritin synthesis in mouse peritoneal macrophages. , 2001, Biochimica et biophysica acta.

[14]  N. Lee,et al.  Identification of c-myc responsive genes using rat cDNA microarray. , 2000, Cancer research.

[15]  L. Chau,et al.  Differential regulation of H- and L-ferritin messenger RNA subunits, ferritin protein and iron following focal cerebral ischemia–reperfusion , 2000, Neuroscience.

[16]  J. Connor,et al.  Interleukin-1beta increases binding of the iron regulatory protein and the synthesis of ferritin by increasing the labile iron pool. , 2000, Biochimica et biophysica acta.

[17]  L. N. Valenti,et al.  Relationship between TNF‐α and iron metabolism in differentiating human monocytic THP‐1 cells , 2000 .

[18]  A. Albertini,et al.  Overexpression of Wild Type and Mutated Human Ferritin H-chain in HeLa Cells , 2000, The Journal of Biological Chemistry.

[19]  M. Tomaro,et al.  Heme oxygenase induction by menadione bisulfite adduct-generated oxidative stress in rat liver. , 2000, Comparative biochemistry and physiology. Toxicology & pharmacology : CBP.

[20]  F. Torti,et al.  Coordinate Transcriptional and Translational Regulation of Ferritin in Response to Oxidative Stress , 2000, Molecular and Cellular Biology.

[21]  Elizabeth C. Theil,et al.  Identification and Characterization of the Iron Regulatory Element in the Ferritin Gene of a Plant (Soybean)* , 2000, The Journal of Biological Chemistry.

[22]  W. Linert,et al.  Redox reactions of neurotransmitters possibly involved in the progression of Parkinson's Disease. , 2000, Journal of inorganic biochemistry.

[23]  Arosio,et al.  A new mutation (G51C) in the iron‐responsive element (IRE) of l‐ferritin associated with hyperferritinaemia–cataract syndrome decreases the binding affinity of the mutated IRE for iron‐regulatory proteins , 2000, British journal of haematology.

[24]  E. Jauniaux,et al.  Localization of p43 placental isoferritin in human maternal-fetal tissue interface. , 2000, American journal of obstetrics and gynecology.

[25]  A. Brownlie,et al.  Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter , 2000, Nature.

[26]  C. Beaumont,et al.  Early Embryonic Lethality of H Ferritin Gene Deletion in Mice* , 2000, The Journal of Biological Chemistry.

[27]  R J Simpson,et al.  A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. , 2000, Molecular cell.

[28]  J. Carter,et al.  Resistance of hypotransferrinemic mice to hyperoxia-induced lung injury. , 1999, American journal of physiology. Lung cellular and molecular physiology.

[29]  F. Torti,et al.  Adenovirus E1A blocks oxidant‐dependent ferritin induction and sensitizes cells to pro‐oxidant cytotoxicity , 1999, FEBS letters.

[30]  M. Jang,et al.  Regulation of ferritin light chain gene expression by oxidized low-density lipoproteins in human monocytic THP-1 cells. , 1999, Biochemical and biophysical research communications.

[31]  C. Beaumont,et al.  H-ferritin subunit overexpression in erythroid cells reduces the oxidative stress response and induces multidrug resistance properties. , 1999, Blood.

[32]  M. Locke,et al.  Secreted ferritin subunits are of two kinds in insects molecular cloning of cDNAs encoding two major subunits of secreted ferritin from Calpodes ethlius. , 1999, Insect biochemistry and molecular biology.

[33]  L. Chau,et al.  Post-transcriptional Regulation of H-ferritin mRNA , 1999, The Journal of Biological Chemistry.

[34]  M E Conrad,et al.  Iron absorption and transport. , 1999, The American journal of the medical sciences.

[35]  A. Thomson,et al.  Iron-regulatory proteins, iron-responsive elements and ferritin mRNA translation. , 1999, The international journal of biochemistry & cell biology.

[36]  Z. Cabantchik,et al.  The cellular labile iron pool and intracellular ferritin in K562 cells. , 1999, Blood.

[37]  B. Polla,,et al.  Induction of ferritin and heat shock proteins by prostaglandin A1 in human monocytes. Evidence for transcriptional and post-transcriptional regulation. , 1999, European journal of biochemistry.

[38]  L. Wesselius,et al.  Effects of TNF-α and IL-1β on iron metabolism by A549 cells and influence on cytotoxicity. , 1999, American journal of physiology. Lung cellular and molecular physiology.

[39]  H. Sorimachi,et al.  Overexpression of myotonic dystrophy protein kinase in C2C12 myogenic culture involved in the expression of ferritin heavy chain and interleukin-1α mRNAs , 1999, Journal of the Neurological Sciences.

[40]  A. Balas,et al.  Description of a new mutation in the L-ferrin iron-responsive element associated with hereditary hyperferritinemia-cataract syndrome in a Spanish family. , 1999, Blood.

[41]  G. Condorelli,et al.  The B Subunit of the CAAT-binding Factor NFY Binds the Central Segment of the Co-activator p300* , 1999, The Journal of Biological Chemistry.

[42]  B. Dunkov,et al.  Iron availability dramatically alters the distribution of ferritin subunit messages in Drosophila melanogaster. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[43]  M. Hentze,et al.  Inactivation of Both RNA Binding and Aconitase Activities of Iron Regulatory Protein-1 by Quinone-induced Oxidative Stress* , 1999, The Journal of Biological Chemistry.

[44]  E. Hanson,et al.  Hypoxia Post-translationally Activates Iron-regulatory Protein 2* , 1999, The Journal of Biological Chemistry.

[45]  K. Bridges,et al.  Hypoxia Alters Iron-regulatory Protein-1 Binding Capacity and Modulates Cellular Iron Homeostasis in Human Hepatoma and Erythroleukemia Cells* , 1999, The Journal of Biological Chemistry.

[46]  Kou-Juey Wu,et al.  Coordinated regulation of iron-controlling genes, H-ferritin and IRP2, by c-MYC. , 1999, Science.

[47]  J. Groopman,et al.  Development of cancer chemopreventive agents: oltipraz as a paradigm. , 1999, Chemical research in toxicology.

[48]  J. Barton,et al.  Coinheritance of alleles associated with hemochromatosis and hereditary hyperferritinemia-cataract syndrome. , 1998, Blood.

[49]  M. C. Faniello,et al.  P/CAF/p300 complex binds the promoter for the heavy subunit of ferritin and contributes to its tissue-specific expression. , 1998, The Biochemical journal.

[50]  Ö. Melefors,et al.  Drosophila ferritin mRNA: alternative RNA splicing regulates the presence of the iron‐responsive element , 1998, FEBS letters.

[51]  Elizabeth C. Theil,et al.  Loops and Bulge/Loops in Iron-responsive Element Isoforms Influence Iron Regulatory Protein Binding , 1998, The Journal of Biological Chemistry.

[52]  M. Hentze,et al.  Activation of iron regulatory protein-1 by oxidative stress in vitro. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[53]  K. Yeh,et al.  Expression of intestinal brush-border membrane hydrolases and ferritin after segmental ischemia-reperfusion in rats. , 1998, American journal of physiology. Gastrointestinal and liver physiology.

[54]  M. Carraway,et al.  Induction of ferritin and heme oxygenase-1 by endotoxin in the lung. , 1998, American journal of physiology. Lung cellular and molecular physiology.

[55]  C. Scaletta,et al.  Evidence that ferritin is UV inducible in human skin: part of a putative defense mechanism. , 1998, The Journal of investigative dermatology.

[56]  C. Beaumont,et al.  Role of Ferritin in the Control of the Labile Iron Pool in Murine Erythroleukemia Cells* , 1998, The Journal of Biological Chemistry.

[57]  D. Birk,et al.  Nuclear ferritin protects DNA from UV damage in corneal epithelial cells. , 1998, Molecular biology of the cell.

[58]  C. Mancuso,et al.  The secondary alcohol metabolite of doxorubicin irreversibly inactivates aconitase/iron regulatory protein‐1 in cytosolic fractions from human myocardium , 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[59]  R. Klausner,et al.  Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[60]  R. Kolter,et al.  The crystal structure of Dps, a ferritin homolog that binds and protects DNA , 1998, Nature Structural Biology.

[61]  E. Hanson,et al.  Regulation of Iron Regulatory Protein 1 during Hypoxia and Hypoxia/Reoxygenation* , 1998, The Journal of Biological Chemistry.

[62]  J. Russo,et al.  Differential expression of human ferritin H chain gene in immortal human breast epithelial MCF‐10F cells , 1997, Molecular carcinogenesis.

[63]  M. C. Faniello,et al.  Okadaic acid stimulates H ferritin transcription in HeLa cells by increasing the interaction between the p300 CO-activator molecule and the transcription factor Bbf. , 1997, Biochemical and biophysical research communications.

[64]  S. Busfield,et al.  Complex regulation of transferrin receptors during erythropoietin-induced differentiation of J2E erythroid cells--elevated transcription and mRNA stabilisation produce only a modest rise in protein content. , 1997, European journal of biochemistry.

[65]  G. Cairo,et al.  Induction of ferritin synthesis in ischemic-reperfused rat liver: analysis of the molecular mechanisms. , 1997, Gastroenterology.

[66]  B. Quaresima,et al.  A Common Mechanism Underlying the E1A Repression and the cAMP Stimulation of the H Ferritin Transcription* , 1997, The Journal of Biological Chemistry.

[67]  H. Beinert,et al.  An EPR Investigation of the Products of the Reaction of Cytosolic and Mitochondrial Aconitases with Nitric Oxide* , 1997, The Journal of Biological Chemistry.

[68]  Stephan Nussberger,et al.  Cloning and characterization of a mammalian proton-coupled metal-ion transporter , 1997, Nature.

[69]  M. Cazzola,et al.  Hereditary hyperferritinemia-cataract syndrome: relationship between phenotypes and specific mutations in the iron-responsive element of ferritin light-chain mRNA. , 1997, Blood.

[70]  W. Wasserman,et al.  Functional antioxidant responsive elements. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[71]  D. Birk,et al.  Ferritin Is a Developmentally Regulated Nuclear Protein of Avian Corneal Epithelial Cells* , 1997, The Journal of Biological Chemistry.

[72]  E. Coccia,et al.  Transcriptional regulation of the ferritin heavy-chain gene: the activity of the CCAAT binding factor NF-Y is modulated in heme-treated Friend leukemia cells and during monocyte-to-macrophage differentiation , 1997, Molecular and cellular biology.

[73]  J. Schalken,et al.  Differential expression of ferritin heavy chain in a rat transitional cell carcinoma progression model. , 1997, Biochimica et biophysica acta.

[74]  Günter Weiss,et al.  Regulation of cellular iron metabolism by erythropoietin: activation of iron-regulatory protein and upregulation of transferrin receptor expression in erythroid cells. , 1997, Blood.

[75]  F. Torti,et al.  Role of H and L Subunits in Mouse Ferritin* , 1996, The Journal of Biological Chemistry.

[76]  J. Briat,et al.  Post‐transcriptional regulation of plant ferritin accumulation in response to iron as observed in the maize mutant ys1 , 1996, FEBS letters.

[77]  J. Zweier,et al.  Induction of hepatic heme oxygenase-1 and ferritin in rats by cancer chemopreventive dithiolethiones. , 1996, Carcinogenesis.

[78]  H. Malech,et al.  Nitric oxide alters the expression of gamma-globin, H-ferritin, and transferrin receptor in human K562 cells at the posttranscriptional level. , 1996, Blood.

[79]  P. Schüssler,et al.  Ferritin mRNAs in Schistosoma mansoni do not have iron-responsive elements for post-transcriptional regulation. , 1996, European journal of biochemistry.

[80]  P. Jeanjean,et al.  A novel mutation in the iron responsive element of ferritin L-subunit gene as a cause for hereditary hyperferritinemia-cataract syndrome. , 1996, Blood.

[81]  G. Minotti,et al.  Superoxide and hydrogen peroxide‐dependent inhibition of iron regulatory protein activity: a protective stratagem against oxidative injury , 1996, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[82]  M. Hentze,et al.  Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[83]  P. Harrison,et al.  The ferritins: molecular properties, iron storage function and cellular regulation. , 1996, Biochimica et biophysica acta.

[84]  Y. Itoyama,et al.  Embryonic genes expressed in Alzheimer's disease brains , 1996, Neuroscience Letters.

[85]  P. Leedman,et al.  Thyroid Hormone Modulates the Interaction between Iron Regulatory Proteins and the Ferritin mRNA Iron-responsive Element (*) , 1996, The Journal of Biological Chemistry.

[86]  Y. L. Chen,et al.  Increased ferritin gene expression in atherosclerotic lesions. , 1996, The Journal of clinical investigation.

[87]  L. Kühn,et al.  Induction of Ferritin Synthesis in Cells Infected with Mengo Virus (*) , 1996, The Journal of Biological Chemistry.

[88]  R. Eisenstein,et al.  Phosphorylation and Activation of both Iron Regulatory Proteins 1 and 2 in HL-60 Cells (*) , 1996, The Journal of Biological Chemistry.

[89]  M. Hentze,et al.  Overexpression of the ferritin H subunit in cultured erythroid cells changes the intracellular iron distribution. , 1996, Blood.

[90]  C. Beaumont,et al.  Mutation in the iron responsive element of the L ferritin mRNA in a family with dominant hyperferritinaemia and cataract , 1995, Nature Genetics.

[91]  D. Girelli,et al.  Molecular basis for the recently described hereditary hyperferritinemia-cataract syndrome: a mutation in the iron-responsive element of ferritin L-subunit gene (the "Verona mutation") , 1995, Blood.

[92]  S. Pignata,et al.  Transcriptional activation of the H-ferritin gene in differentiated Caco-2 cells parallels a change in the activity of the nuclear factor Bbf. , 1995, The Biochemical journal.

[93]  P. Maurel,et al.  Differential effects of cytokines on the inducible expression of CYP1A1, CYP1A2, and CYP3A4 in human hepatocytes in primary culture , 1995, Hepatology.

[94]  Y. Nakabeppu,et al.  FER-1, an enhancer of the ferritin H gene and a target of E1A-mediated transcriptional repression , 1995, Molecular and cellular biology.

[95]  E. Coccia,et al.  Regulation of ferritin H-chain expression in differentiating Friend leukemia cells. , 1995, Blood.

[96]  C. Beaumont,et al.  Role for NF-κB in the Regulation of Ferritin H by Tumor Necrosis Factor-α (*) , 1995, The Journal of Biological Chemistry.

[97]  M. Hentze,et al.  Rapid responses to oxidative stress mediated by iron regulatory protein. , 1995, The EMBO journal.

[98]  Yanjun Qi,et al.  Hypoxia Alters Iron Homeostasis and Induces Ferritin Synthesis in Oligodendrocytes , 1995, Journal of neurochemistry.

[99]  D. Drucker,et al.  UVB radiation-activated genes induced by transcriptional and posttranscriptional mechanisms in rat keratinocytes. , 1995, The American journal of physiology.

[100]  A. Tomasi,et al.  Induction of Ferritin Synthesis by Oxidative Stress , 1995, The Journal of Biological Chemistry.

[101]  Yanjun Qi,et al.  Hypoxia Specifically and Reversibly Induces the Synthesis of Ferritin in Oligodendrocytes and Human Oligodendrogliomas , 1994, Journal of neurochemistry.

[102]  Jack T. Rogers,et al.  Translational enhancement of H-ferritin mRNA by interleukin-1 beta acts through 5' leader sequences distinct from the iron responsive element , 1994, Nucleic Acids Res..

[103]  J. Cook,et al.  Large amount of (Apo)ferritin in the pancreatic insulin cell and its stimulation by glucose , 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[104]  M. C. Faniello,et al.  Transcriptional regulation of the human H ferritin-encoding gene (FERH) in G418-treated cells: role of the B-box-binding factor. , 1994, Gene.

[105]  R. Ravazzolo,et al.  A negative cis-acting G-fer element participates in the regulation of expression of the human H-ferritin-encoding gene (FERH). , 1994, Gene.

[106]  N. Gray,et al.  Recombinant iron-regulatory factor functions as an iron-responsive-element-binding protein, a translational repressor and an aconitase. A functional assay for translational repression and direct demonstration of the iron switch. , 1993, European journal of biochemistry.

[107]  S. Young,et al.  Modulation of iron metabolism in monocyte cell line U937 by inflammatory cytokines: changes in transferrin uptake, iron handling and ferritin mRNA. , 1993, The Biochemical journal.

[108]  G. Vercellotti,et al.  Tumor cell heme uptake induces ferritin synthesis resulting in altered oxidant sensitivity: possible role in chemotherapy efficacy. , 1993, Cancer research.

[109]  Y. Kohgo,et al.  Regulation of iron metabolism in HepG2 cells: A possible role for cytokines in the hepatic deposition of iron , 1993, Hepatology.

[110]  R. Pilz Impaired erythroid-specific gene expression in cAMP-dependent protein kinase-deficient murine erythroleukemia cells. , 1993, The Journal of biological chemistry.

[111]  J. Drapier,et al.  Biosynthesis of nitric oxide activates iron regulatory factor in macrophages. , 1993, The EMBO journal.

[112]  G Werner-Felmayer,et al.  Translational regulation via iron‐responsive elements by the nitric oxide/NO‐synthase pathway. , 1993, The EMBO journal.

[113]  T. Saika,et al.  Preferential repression of the H subunit of ferritin by adenovirus E1A in NIH-3T3 mouse fibroblasts. , 1993, The Journal of biological chemistry.

[114]  Ç. Yenisey,et al.  Cytosol and serum ferritin in breast carcinoma. , 1992, Cancer letters.

[115]  Yanjun Qi,et al.  Hypoxia Induces Synthesis of a Novel 22‐kDa Protein in Neonatal Rat Oligodendrocytes , 1992, Journal of neurochemistry.

[116]  M. Schemper,et al.  Expression of p43 in breast cancer tissue, correlation with prognostic parameters. , 1992, Cancer letters.

[117]  T. Kumagai,et al.  Mobilization of iron and iron-related proteins in rat spleen after intravenous injection of lipopolysaccharides (LPS). , 1992, Pathology, research and practice.

[118]  J. Eaton,et al.  Ferritin: a cytoprotective antioxidant strategem of endothelium. , 1992, The Journal of biological chemistry.

[119]  R. Fleischmann,et al.  Isolation and characterization of gene sequences overexpressed in werner syndrome fibroblasts during premature replicative senescence , 1992, Experimental Gerontology.

[120]  T. Frebourg,et al.  Increased expression of cytokeratin and ferritin-H genes in tumorigenic clones of the SW 613-S human colon carcinoma cell line. , 1992, Experimental cell research.

[121]  D. Remick,et al.  Cytokines in Health and Disease , 1992 .

[122]  F. Cimino,et al.  Promoter for the human ferritin heavy chain-encoding gene (FERH): structural and functional characterization. , 1992, Gene.

[123]  G. Liau,et al.  Increased ferritin gene expression is both promoted by cAMP and a marker of growth arrest in rabbit vascular smooth muscle cells. , 1991, The Journal of biological chemistry.

[124]  F. Torti,et al.  Iron-independent induction of ferritin H chain by tumor necrosis factor. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[125]  Elizabeth C. Theil,et al.  Ferritin mRNA: interactions of iron regulatory element with translational regulator protein P-90 and the effect on base-paired flanking regions. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[126]  T. Onaya,et al.  Transcriptional regulation of ferritin messenger ribonucleic acid levels by insulin in cultured rat glioma cells. , 1991, Endocrinology.

[127]  H. Munro,et al.  Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[128]  M. Shingu,et al.  Correlation of metal-binding proteins and proteinase inhibitors with immunological parameters in rheumatoid synovial fluids. , 1990, Clinical and experimental rheumatology.

[129]  H. Munro,et al.  Translational control during the acute phase response. Ferritin synthesis in response to interleukin-1. , 1990, The Journal of biological chemistry.

[130]  D. Foti,et al.  Thyrotropin and adenosine 3',5'-monophosphate stimulate the activity of the ferritin-H promoter. , 1990, Molecular endocrinology.

[131]  F. Torti,et al.  Interleukin 1 induces ferritin heavy chain in human muscle cells. , 1990, Biochemical and biophysical research communications.

[132]  J. D. Den Blaauwen,et al.  Role of protein synthesis in the accumulation of ferritin mRNA during exposure of cells to iron. , 1990, The Biochemical journal.

[133]  T. Onaya,et al.  Transcriptional regulation of ferritin heavy chain messenger RNA expression by thyroid hormone. , 1990, Biochemical and biophysical research communications.

[134]  B. Rapoport,et al.  Transcriptional regulation of ferritin H messenger RNA levels in FRTL5 rat thyroid cells by thyrotropin. , 1990, The Journal of biological chemistry.

[135]  G. Colletta,et al.  Thyrotropin stimulates transcription from the ferritin heavy chain promoter. , 1989, Biochemical and biophysical research communications.

[136]  C. Moroz,et al.  Expression of messenger RNA species coding for a Mr 43,000 peptide associated with ferritin in human leukemia-K562 cells and its down regulation during differentiation. , 1989, Cancer research.

[137]  P. Artymiuk,et al.  Identification of the ferroxidase centre in ferritin , 1989, FEBS letters.

[138]  C. Beaumont,et al.  Transcriptional regulation of ferritin H and L subunits in adult erythroid and liver cells from the mouse. Unambiguous identification of mouse ferritin subunits and in vitro formation of the ferritin shells. , 1989, The Journal of biological chemistry.

[139]  G. Ashwell,et al.  Multiple post-transcriptional regulatory mechanisms in ferritin gene expression. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[140]  S. Daniels-McQueen,et al.  Translational repression in eukaryotes: partial purification and characterization of a repressor of ferritin mRNA translation. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[141]  K. Myambo,et al.  The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor-inducible gene. , 1988, The Journal of biological chemistry.

[142]  H. Munro,et al.  Induction of ferritin subunit synthesis by iron is regulated at both the transcriptional and translational levels. , 1988, The Journal of biological chemistry.

[143]  B. Rapoport,et al.  Molecular cloning of cDNA corresponding to mRNA species whose steady state levels in the thyroid are enhanced by thyrotropin. Homology of one of these sequences with ferritin H. , 1988, The Journal of biological chemistry.

[144]  R D Klausner,et al.  Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation. , 1988, Science.

[145]  P. Arosio,et al.  Mechanisms of regulation of ferritin synthesis in rat liver during experimental inflammation. , 1988, Experimental and molecular pathology.

[146]  H. Munro,et al.  Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy- and light-subunit mRNAs. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[147]  V. de Franciscis,et al.  TSH regulation of ferritin H chain messenger RNA levels in the rat thyroids. , 1988, Biochemical and biophysical research communications.

[148]  Z. Darżynkiewicz,et al.  Model for intermediate steps in monocytic differentiation: c-myc, c-fms, and ferritin as markers. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[149]  R D Klausner,et al.  A cis-acting element is necessary and sufficient for translational regulation of human ferritin expression in response to iron. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[150]  S. Jain,et al.  Ferritin synthesis in differentiating Friend erythroleukemic cells. , 1987, The Journal of biological chemistry.

[151]  L. Detolla,et al.  Iron, ferritin, hepatitis B surface and core antigens in the livers of chinese patients with hepatocellular carcinoma , 1987, Cancer.

[152]  H. Munro,et al.  Translation of ferritin light and heavy subunit mRNAs is regulated by intracellular chelatable iron levels in rat hepatoma cells. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[153]  P. Arosio,et al.  Human serum ferritin G‐peptide is recognized by anti‐L ferritin subunit antibodies and concanavalin‐A , 1987, British journal of haematology.

[154]  A. Swaak,et al.  Intraarticular ferritin-bound iron in rheumatoid arthritis. A factor that increases oxygen free radical-induced tissue destruction. , 1986, Arthritis and rheumatism.

[155]  W. Salser,et al.  Structure and expression of ferritin genes in a human promyelocytic cell line that differentiates in vitro , 1986, Molecular and cellular biology.

[156]  H. Munro,et al.  Both subunits of rat liver ferritin are regulated at a translational level by iron induction. , 1986, Nucleic acids research.

[157]  P. Arosio,et al.  Multiple mechanisms of iron-induced ferritin synthesis in HeLa cells. , 1985, Biochemical and biophysical research communications.

[158]  S. Jain,et al.  Ferritin H and L chains are derived from different multigene families. , 1985, The Journal of biological chemistry.

[159]  B. Beutler,et al.  A macrophage factor inhibits adipocyte gene expression: an in vitro model of cachexia. , 1985, Science.

[160]  C. Cohen,et al.  lmmunohistochemical ferritin in testicular seminoma , 1984, Cancer.

[161]  A. Silverstone,et al.  Relative subunit composition of the ferritin synthesized by selected human lymphomyeloid cell populations. , 1983, Experimental hematology.

[162]  Robert A. Weinberg,et al.  Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes , 1983, Nature.

[163]  B. Silberberg,et al.  Tissue ferritin concentration in carcinoma of the breast , 1982, Cancer.

[164]  A. Konijn,et al.  Ferritin Synthesis in Inflammation: II. MECHANISM OF INCREASED FERRITIN SYNTHESIS , 1981, British journal of haematology.

[165]  J. Drysdale,et al.  Ferritinaemia in cancer , 1977, Nature.

[166]  P. Arosio,et al.  Structural and immunological relationships of isoferritins in normal and malignant cells. , 1976, Cancer research.

[167]  H. Munro,et al.  Novel mechanism for translational control in regulation of ferritin synthesis by iron. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[168]  J. Cook,et al.  A clinical evaluation of serum ferritin as an index of iron stores. , 1974, The New England journal of medicine.

[169]  M. Worwood,et al.  Assignment of human ferritin genes to chromosomes 11 and 19q13.3→19qter , 2004, Human Genetics.

[170]  Y. Kan,et al.  Human ferritin light chain gene sequences mapped to several sorted chromosomes , 2004, Human Genetics.

[171]  M. Worwood,et al.  Genes for the ‘H’ subunit of human ferritin are present on a number of human chromosomes , 2004, Human Genetics.

[172]  J. Connor,et al.  Hypoxic/ischemic insult alters ferritin expression and myelination in neonatal rat brains. , 2001, The Journal of comparative neurology.

[173]  S. Sheth,et al.  Genetic disorders affecting proteins of iron metabolism: clinical implications. , 2000, Annual review of medicine.

[174]  R. Eisenstein Iron regulatory proteins and the molecular control of mammalian iron metabolism. , 2000, Annual review of nutrition.

[175]  R. Martino,et al.  Recurrent mutations in the iron regulatory element of L-ferritin in hereditary hyperferritinemia-cataract syndrome. , 1999, Haematologica.

[176]  C. Arosio,et al.  Hereditary hyperferritinemia cataract syndrome: a de novo mutation in the iron responsive element of the L-ferritin gene. , 1999, Haematologica.

[177]  C. Beaumont,et al.  A point mutation in the bulge of the iron-responsive element of the L ferritin gene in two families with the hereditary hyperferritinemia-cataract syndrome. , 1998, Blood.

[178]  T. Vulliamy,et al.  Hereditary hyperferritinemia-cataract syndrome: two novel mutations in the L-ferritin iron-responsive element. , 1998, Blood.

[179]  A. Larsson,et al.  Increased serum concentrations of carbohydrate-deficient transferrin (CDT) in patients with cystic fibrosis. , 1998, Upsala journal of medical sciences.

[180]  Chasteen Nd FERRITIN. UPTAKE, STORAGE, AND RELEASE OF IRON , 1998 .

[181]  N. Chasteen Ferritin. Uptake, storage, and release of iron. , 1998, Metal ions in biological systems.

[182]  M. Linder,et al.  Secretion of ferritin by rat hepatoma cells and its regulation by inflammatory cytokines and iron. , 1997, Blood.

[183]  S. Aust,et al.  Pulmonary ferritin: differential effects of hyperoxic lung injury on subunit mRNA levels. , 1997, Free radical biology & medicine.

[184]  P. Ponka Tissue-specific regulation of iron metabolism and heme synthesis: distinct control mechanisms in erythroid cells. , 1997, Blood.

[185]  P. Reitsma,et al.  Rat ferritin-H: cDNA cloning, differential expression and localization during hepatocarcinogenesis. , 1997, Carcinogenesis.

[186]  H. Beinert,et al.  An EPR investigation of the products of the reaction of cytosolic and mitochondrial aconitases with nitric oxide. , 1997, The Journal of biological chemistry.

[187]  R. Thach,et al.  Effects of the ferritin open reading frame on translational induction by iron. , 1996, Progress in nucleic acid research and molecular biology.

[188]  S. Milani,et al.  Duodenal ferritin synthesis in genetic hemochromatosis. , 1995, Gastroenterology.

[189]  A. Varrone,et al.  Ki-ras oncogene interferes with the expression of cyclic AMP-dependent promoters. , 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[190]  F. Torti,et al.  Iron and ferritin in inflammation and cancer. , 1994, Advances in inorganic biochemistry.

[191]  W. H. Massover Ultrastructure of ferritin and apoferritin: A review , 1993 .

[192]  G. Vercellotti,et al.  Endothelial cell heme oxygenase and ferritin induction by heme proteins: a possible mechanism limiting shock damage. , 1992, Transactions of the Association of American Physicians.

[193]  M. Hentze,et al.  Modulation of ferritin H-chain expression in Friend erythroleukemia cells: transcriptional and translational regulation by hemin. , 1992, Molecular and cellular biology.

[194]  Elizabeth C. Theil The ferritin family of iron storage proteins. , 1990, Advances in enzymology and related areas of molecular biology.

[195]  R. Klausner,et al.  Coordinate post-transcriptional regulation of ferritin and transferrin receptor expression: the role of regulated RNA-protein interaction. , 1990, Enzyme.

[196]  B. Beutler,et al.  The biology of cachectin/TNF--a primary mediator of the host response. , 1989, Annual review of immunology.

[197]  B. Halliwell Protection against oxidants in biological systems : the superoxide theory of oxygen toxicity , 1989 .

[198]  J. Brock,et al.  Iron in immunity, cancer and inflammation , 1989 .

[199]  M. A. Rockwell,et al.  Ferritin content in human cancerous and noncancerous colonic tissue. , 1987, Cancer investigation.

[200]  C. Jones,et al.  Human ferritin gene is assigned to chromosome 19. , 1983, Proceedings of the National Academy of Sciences of the United States of America.