Granular Cell Ameloblastoma: Report of an Unusual Case and Review of Literature

Ameloblastoma is an epithelial odontogenic tumor of the jaws and exhibits diverse microscopic patterns. Granular cell ameloblastoma is a rare variant of ameloblastoma, making up to 3.5% of all ameloblastomas. The granular change is thought to be a dysfunctional status of neoplastic cells leading to degenerative changes in long standing lesions. The pathogenesis of this tumor seems to be related to lysosome like organelles seen as eosinophilic granules in the cytoplasm. The granular cell ameloblastoma, in most instances is found as an admixture with other histologic patterns, particularly follicular subtype. This report describes an unusual case of granular cell ameloblastoma along with a review of literature.

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