Radioiodine Accumulation in a Giant Ovarian Cystadenofibroma Detected Incidentally by 131-I Whole Body Scans

Ovarian cystadenofibroma is a relatively rare tumor; it is usually asymptomatic and is found incidentally. We present the case of a 24-year-old female patient, who had undergone total thyroidectomy for thyroid papillary carcinoma, with an asymptomatic giant cystadenofibroma, incidentally discovered by diagnostic 131I-SPECT/CT WBSs. We summarize the clinical history, imaging data, and histopathological study on a rare case of radioiodine accumulation in cystadenofibroma, and we discuss the mechanism of uptake of radioiodine in this case.

[1]  Quan-Yong Luo,et al.  Abnormal ¹³¹I uptake in a benign serous ovarian cystadenoma mimicking bladder physiological uptake. , 2012, Clinical nuclear medicine.

[2]  D. Katz,et al.  False-positive I-131 uptake by an ovarian serous cystadenofibroma. , 2012, Clinical nuclear medicine.

[3]  K. Nakajima,et al.  Double-phase 131I whole body scan and 131I SPECT-CT images in patients with differentiated thyroid cancer: their effectiveness for accurate identification , 2011, Annals of nuclear medicine.

[4]  R. Halkar,et al.  I-131 Uptake in an Endometriotic Ovarian Cyst in a Patient With Papillary Thyroid Carcinoma , 2010 .

[5]  K. Kumanlıoğlu,et al.  Radioiodine accumulation in a large adnexal cystadenofibroma. , 2010, Thyroid : official journal of the American Thyroid Association.

[6]  O. Kraft,et al.  I-131 uptake in an ovarian tumor: differential diagnosis for abdominal I-131 uptake. , 2009, Clinical nuclear medicine.

[7]  Giuseppe Madeddu,et al.  131I SPECT/CT in the Follow-up of Differentiated Thyroid Carcinoma: Incremental Value Versus Planar Imaging , 2009, Journal of Nuclear Medicine.

[8]  Hwan-Jeong Jeong,et al.  Malignant struma ovarii demonstrated on post-therapy radioiodine scan after total thyroidectomy for papillary thyroid cancer. , 2008, Clinical nuclear medicine.

[9]  A. Driedger,et al.  Iodine-131 uptake in a menstruating uterus: value of SPECT/CT in distinguishing benign and metastatic iodine-positive lesions. , 2007, Thyroid : official journal of the American Thyroid Association.

[10]  S. Shiraishi,et al.  Struma Ovarii Coexisting With Mucinous Cystadenoma Detected by Radioactive Iodine , 2003, Clinical nuclear medicine.

[11]  I. Mcdougall,et al.  The interpretation of 131I scans in the evaluation of thyroid cancer, with an emphasis on false positive findings. , 2003, Nuclear medicine communications.

[12]  V. Rohmer,et al.  Abnormal iodine-131 uptake in a benign mucinous ovarian cystadenoma mimicking struma ovarii. , 2007, Clinical nuclear medicine.