Advances of capillary electrophoresis in clinical and forensic analysis (1999–2000)

In this paper, capillary electrophoresis in clinical and forensic analysis is reviewed on the basis of the literature of 1999, 2000 and the first papers in 2001. An overview of progress and relevant examples for each major field of application, namely (i) analysis of drug seizures, explosives residues, gunshot residues and inks, (ii) monitoring of drugs, endogenous small molecules and ions in biofluids and tissues, (iii) general screening for serum proteins and analysis of specific proteins (carbohydrate deficient transferrin, α1‐antitrypsin, lipoproteins and hemoglobins) in biological fluids, and (iv) analysis of nucleic acids and oligonucleotides in biological samples, including oligonucleotide therapeutics, are presented.

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[66]  F. Zunino,et al.  Single‐strand conformation polymorphism analysis by capillary zone electrophoresis in neutral pH buffer , 2000, Electrophoresis.

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[75]  Kwan Jun Lee,et al.  Determination of enantiomeric amphetamines as metabolites of illicit amphetamines and selegiline in urine by capillary electrophoresis using modified beta-cyclodextrin. , 2000, Journal of chromatography. B, Biomedical sciences and applications.

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[88]  G. Hempel,et al.  Determination of (E)-5-(2-bromovinyl)-2'-deoxyuridine in plasma and urine by capillary electrophoresis. , 1999, Journal of chromatography. B, Biomedical sciences and applications.

[89]  Sam F. Y. Li,et al.  Indirect laser‐induced fluorescence detection of valproic acid in human serum by capillary electrophoresis , 1999, Electrophoresis.

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[116]  W. Thormann,et al.  Stereoselective screening for and confirmation of urinary enantiomers of amphetamine, methamphetamine, designer drugs, methadone and selected metabolites by capillary electrophoresis , 1999, Electrophoresis.

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[127]  A. Van Schepdael,et al.  Capillary electrophoresis of RNA oligonucleotides: catalytic activity of a hammerhead ribozyme. , 1999, Analytical biochemistry.

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[173]  W. Thormann,et al.  Therapeutic drug monitoring of albendazole: Determination of albendazole, albendazole sulfoxide, and albendazole sulfone in human plasma using nonaqueous capillary electrophoresis , 2000, Electrophoresis.

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[179]  I. Lurie,et al.  Use of dynamically coated capillaries for the routine analysis of methamphetamine, amphetamine, MDA, MDMA, MDEA, and cocaine using capillary electrophoresis. , 2001, Journal of forensic sciences.

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[184]  P. Andresen,et al.  Assay of tramadol in urine by capillary electrophoresis using laser-induced native fluorescence detection. , 2000, Journal of chromatography. B, Biomedical sciences and applications.

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