The effects of progressive strength training and aerobic exercise on muscle strength and cardiovascular fitness in women with fibromyalgia: a pilot study.

OBJECTIVE To determine the safety, feasibility and consequences of a program of progressive strength training and cardiovascular exercise in women with fibromyalgia syndrome (FMS). METHODS Fifteen women with confirmed FMS were monitored for injury and exercise compliance, and assessed for muscle strength (1-repetition maximum technique), cardiovascular endurance (6-minute walk test), and functional status (Fibromyalgia Impact Questionnaire [FIQ]) before and after a 20-week exercise intervention. RESULTS Zero injuries and an 81% compliance rate occurred during training. Improvement was seen in muscle strength of the lower (191 +/- 75 to 265 +/- 67 pounds; P < 0.001) and upper (61 +/- 18 to 76 +/- 18 pounds; P < 0.001) body, 6-minute walk distance (530 +/- 80 to 629 +/- 74 meters; P < 0.001), and in FIQ score (44 +/- 9 to 32 +/- 14; P < 0.01). CONCLUSION A program of progressive strength training and cardiovascular exercise can be safe, well tolerated, and effective at improving muscle strength, cardiovascular endurance and functional status in women with FMS without exacerbating symptoms. This program may also contribute to a reduction in the severity of several symptoms.

[1]  J. Mehlsen,et al.  Muscle strength, working capacity and effort in patients with fibromyalgia. , 1997, Scandinavian journal of rehabilitation medicine.

[2]  Scott Thomas,et al.  The Canadian Home Fitness Test , 1976, Canadian Medical Association journal.

[3]  R M Bennett,et al.  The fibromyalgia impact questionnaire: development and validation. , 1991, The Journal of rheumatology.

[4]  R. Bennett,et al.  Increased incidence of a resonance in the phosphodiester region of 31P nuclear magnetic resonance spectra in the skeletal muscle of fibromyalgia patients. , 1994, Arthritis and rheumatism.

[5]  R. Bennett,et al.  A prospective, longitudinal, multicenter study of service utilization and costs in fibromyalgia. , 1997, Arthritis and rheumatism.

[6]  S. R. Clark,et al.  Prescribing exercise for fibromyalgia patients. , 1994, Arthritis care and research : the official journal of the Arthritis Health Professions Association.

[7]  R. Simms Controlled trials of therapy in fibromyalgia syndrome. , 1994, Bailliere's clinical rheumatology.

[8]  A. M. Mengshoel,et al.  The effects of 20 weeks of physical fitness training in female patients with fibromyalgia. , 1992, Clinical and experimental rheumatology.

[9]  H. Moldofsky,et al.  Induction of Neurasthenic Musculoskeletal Pain Syndrome by Selective Sleep Stage Deprivation , 1976, Psychosomatic medicine.

[10]  J. Mehlsen,et al.  Biochemical changes in relation to a maximal exercise test in patients with fibromyalgia. , 1994, Clinical physiology.

[11]  Y. Bhambhani,et al.  Validity and reliability of the 6 minute walk in persons with fibromyalgia. , 1999, The Journal of rheumatology.

[12]  B. Danneskiold-Samsøe,et al.  Isokinetic and isometric muscle strength combined with transcutaneous electrical muscle stimulation in primary fibromyalgia syndrome. , 1991, The Journal of rheumatology.

[13]  C. Thomsen,et al.  Muscle strength, voluntary activation and cross-sectional muscle area in patients with fibromyalgia. , 1995, British journal of rheumatology.

[14]  Gerda G. Fillenbaum,et al.  Multidimensional Functional Assessment of Older Adults: The Duke Older Americans Resources and Services Procedures , 1988 .

[15]  S B Roberts,et al.  Exercise training and nutritional supplementation for physical frailty in very elderly people. , 1994, The New England journal of medicine.

[16]  F. Keefe,et al.  Self-management of fibromyalgia: the role of formal coping skills training and physical exercise training programs. , 1998, Arthritis care and research : the official journal of the Arthritis Health Professions Association.

[17]  C. Burckhardt,et al.  A randomized, controlled clinical trial of education and physical training for women with fibromyalgia. , 1994, The Journal of rheumatology.

[18]  Serge H. Roy,et al.  Lack of association between fibromyalgia syndrome and abnormalities in muscle energy metabolism. , 1994, Arthritis and rheumatism.

[19]  N. Vøllestad,et al.  Pain and fatigue induced by exercise in fibromyalgia patients and sedentary healthy subjects. , 1995, Clinical and experimental rheumatology.

[20]  R. Shephard,et al.  The Canadian Home Fitness Test. 1991 update. , 1991, Sports medicine.

[21]  Strength conditioning in older men: skeletal muscle hypertrophy and improved function. , 1988 .

[22]  M. Fiatarone,et al.  Effects of High-Intensity Strength Training on Multiple Risk Factors for Osteoporotic Fractures: A Randomized Controlled Trial , 1994 .

[23]  B. MacIntosh,et al.  An exercise program in the treatment of fibromyalgia. , 1996, The Journal of rheumatology.

[24]  J. Moreland,et al.  A comparative evaluation of a fibromyalgia rehabilitation program. , 1999, Arthritis care and research : the official journal of the Arthritis Health Professions Association.

[25]  L. Lipsitz,et al.  High-intensity strength training in nonagenarians. Effects on skeletal muscle. , 1990, JAMA.

[26]  K. Häkkinen,et al.  Force production capacity and acute neuromuscular responses to fatiguing loading in women with fibromyalgia are not different from those of healthy women. , 2000, The Journal of rheumatology.

[27]  G. A. Mccain,et al.  A controlled study of the effects of a supervised cardiovascular fitness training program on the manifestations of primary fibromyalgia. , 1988, Arthritis and rheumatism.

[28]  R. McKelvie,et al.  Usefulness of weightlifting training in improving strength and maximal power output in coronary artery disease. , 1991, The American journal of cardiology.

[29]  April Rasala Lehman,et al.  A Guide to Statistical and Data Analysis Using JMP and JMP IN Software , 1999 .

[30]  M. Richardson,et al.  A randomized, controlled trial of exercise and education for individuals with fibromyalgia. , 1999, Arthritis care and research : the official journal of the Arthritis Health Professions Association.

[31]  R. Bennett,et al.  Aerobic fitness in patients with fibrositis. A controlled study of respiratory gas exchange and 133xenon clearance from exercising muscle. , 1989, Arthritis and rheumatism.

[32]  M. Yunus,et al.  Pathologic changes in muscle in primary fibromyalgia syndrome. , 1986, The American journal of medicine.

[33]  D. Nichols,et al.  Effects of aerobic exercise on pain perception, affect, and level of disability in individuals with fibromyalgia. , 1994, Physical therapy.

[34]  G. Grimby,et al.  Studies on maximal voluntary muscle contraction in patients with fibromyalgia. , 1994, Archives of physical medicine and rehabilitation.

[35]  W. Hayes,et al.  Self-Paced Exercise and Neuromotor Performance in Community-Dwelling Older Adults , 1997 .

[36]  G. A. Mccain Role of physical fitness training in the fibrositis/fibromyalgia syndrome. , 1986, The American journal of medicine.

[37]  W. Wilke Fibromyalgia. Recognizing and addressing the multiple interrelated factors. , 1996, Postgraduate medicine.

[38]  D. Kiel,et al.  Self-paced resistance training and walking exercise in community-dwelling older adults: effects on neuromotor performance. , 1997, The journals of gerontology. Series A, Biological sciences and medical sciences.

[39]  R. Bennett,et al.  Group treatment of fibromyalgia: a 6 month outpatient program. , 1996, The Journal of rheumatology.

[40]  Reiffenberger Dh,et al.  Fibromyalgia syndrome: a review. , 1996 .

[41]  G. Borg Psychophysical bases of perceived exertion. , 1982, Medicine and science in sports and exercise.

[42]  P. Tugwell,et al.  The American College of Rheumatology 1990 Criteria for the Classification of Fibromyalgia. Report of the Multicenter Criteria Committee. , 1990, Arthritis and rheumatism.

[43]  Strength training in a cardiac rehabilitation program: a six-month follow-up. , 1990, Archives of physical medicine and rehabilitation.

[44]  R. Bennett,et al.  Health status and disease severity in fibromyalgia: results of a six-center longitudinal study. , 1997, Arthritis and rheumatism.