Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography

[1]  T. Kitamoto,et al.  Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women , 2011, Journal of Human Genetics.

[2]  T. Kitamoto,et al.  Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area , 2011, Journal of Human Genetics.

[3]  Mark I McCarthy,et al.  Genomics, type 2 diabetes, and obesity. , 2010, The New England journal of medicine.

[4]  Yusuke Nakamura,et al.  Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population , 2010, Journal of Human Genetics.

[5]  Y. Aulchenko,et al.  Association between Type 2 Diabetes Loci and Measures of Fatness , 2010, PloS one.

[6]  F. Collins,et al.  Potential etiologic and functional implications of genome-wide association loci for human diseases and traits , 2009, Proceedings of the National Academy of Sciences.

[7]  Suzette J. Bielinski,et al.  NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE Consortium , 2009, PLoS genetics.

[8]  P. O’Reilly,et al.  Genome-wide association study identifies eight loci associated with blood pressure , 2009, Nature Genetics.

[9]  Andrew D. Johnson,et al.  Genome-wide association study of blood pressure and hypertension , 2009, Nature Genetics.

[10]  Laura J. Scott,et al.  Edinburgh Research Explorer Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution , 2022 .

[11]  Zhuoyou Chen,et al.  Variants in KCNQ1 are associated with susceptibility to type 2 diabetes in the population of mainland China , 2009, Diabetologia.

[12]  J. Norris,et al.  Analysis of FTO gene variants with measures of obesity and glucose homeostasis in the IRAS Family Study , 2009, Human Genetics.

[13]  Barbara Heude,et al.  Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations , 2009, Nature Genetics.

[14]  William C. Knowler,et al.  Association Analysis of Variation in/Near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B With Type 2 Diabetes and Related Quantitative Traits in Pima Indians , 2009, Diabetes.

[15]  K. Midthjell,et al.  Comparison of genetic risk in three candidate genes (TCF7L2, PPARG, KCNJ11) with traditional risk factors for type 2 diabetes in a population‐based study – the HUNT study , 2009, Scandinavian Journal of Clinical and Laboratory Investigation.

[16]  T. Hansen,et al.  SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations , 2008, Nature Genetics.

[17]  L. Groop,et al.  Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus , 2008, Nature Genetics.

[18]  T. Hansen,et al.  FTO Gene Associated Fatness in Relation to Body Fat Distribution and Metabolic Traits throughout a Broad Range of Fatness , 2008, PloS one.

[19]  F. Schick,et al.  Impact of Variation in the FTO Gene on Whole Body Fat Distribution, Ectopic Fat, and Weight Loss , 2008, Obesity.

[20]  H. Shin,et al.  Implication of Genetic Variants Near TCF7L2, SLC30A8, HHEX, CDKAL1, CDKN2A/B, IGF2BP2, and FTO in Type 2 Diabetes and Obesity in 6,719 Asians , 2008, Diabetes.

[21]  M. McCarthy,et al.  Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes , 2008, Nature Genetics.

[22]  G. Beunen,et al.  Anthropometry, carbohydrate and lipid metabolism in the East Flanders Prospective Twin Survey: heritabilities , 2007, Diabetologia.

[23]  Simon C. Potter,et al.  Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls , 2007, Nature.

[24]  Marcia M. Nizzari,et al.  Genome-Wide Association Analysis Identifies Loci for Type 2 Diabetes and Triglyceride Levels , 2007, Science.

[25]  M. Jarvelin,et al.  A Common Variant in the FTO Gene Is Associated with Body Mass Index and Predisposes to Childhood and Adult Obesity , 2007, Science.

[26]  T. Hudson,et al.  A genome-wide association study identifies novel risk loci for type 2 diabetes , 2007, Nature.

[27]  Y. Ouchi,et al.  Prevalence of metabolic syndrome in the general Japanese population in 2000. , 2006, Journal of atherosclerosis and thrombosis.

[28]  H. Stefánsson,et al.  Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes , 2006, Nature Genetics.

[29]  Y. Matsuzawa.  Metabolic syndrome--definition and diagnostic criteria in Japan. , 2005, Journal of atherosclerosis and thrombosis.

[30]  Jane B Shofer,et al.  Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome. , 2004, Diabetes.

[31]  Yusuke Nakamura,et al.  A high-throughput SNP typing system for genome-wide association studies , 2001, Journal of Human Genetics.

[32]  T. Funahashi,et al.  Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. , 2001, Diabetes.

[33]  S. Yamashita,et al.  Abdominal fat: standardized technique for measurement at CT. , 1999, Radiology.

[34]  J. Selby,et al.  Genetic and behavioral determinants of waist-hip ratio and waist circumference in women twins. , 1998, Obesity research.

[35]  M. Ehm,et al.  Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus. , 1998, American journal of human genetics.

[36]  D. Carmelli,et al.  Genetic and behavioral influences on body fat distribution. , 1990, International journal of obesity.

[37]  D. Altshuler,et al.  Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion , 2009, Nature Genetics.

[38]  Christian Gieger,et al.  Six new loci associated with body mass index highlight a neuronal influence on body weight regulation , 2009, Nature Genetics.

[39]  Ellen Kampman,et al.  Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity , 2009, Nature Genetics.

[40]  K. Mossman.  The Wellcome Trust Case Control Consortium, U.K. , 2008 .

[41]  Y. Matsuzawa.  Therapy Insight: adipocytokines in metabolic syndrome and related cardiovascular disease , 2006, Nature Clinical Practice Cardiovascular Medicine.