N-Alkyl-N-alkyloxycarbonylaminomethyl (NANAOCAM) prodrugs of carboxylic acid containing drugs.
暂无分享,去创建一个
[1] S. Majumdar,et al. Practical Synthesis of N‐Alkyl‐N‐alkyloxycarbonylaminomethyl Prodrug Derivatives of Acetaminophen, Theophylline, and 6‐Mercaptopurine , 2006 .
[2] S. Majumdar,et al. Synthesis, hydrolyses and dermal delivery of N-alkyl-N-alkyloxycarbonylaminomethyl (NANAOCAM) derivatives of phenol, imide and thiol containing drugs. , 2006, Bioorganic & medicinal chemistry letters.
[3] Scott C. Wasdo,et al. Topical Delivery of a Model Phenolic Drug: Alkyloxycarbonyl Prodrugs of Acetaminophen , 2004, Pharmaceutical Research.
[4] R. Moreira,et al. Acyloxymethyl as a Drug Protecting Group: Part 4. The Hydrolysis of Tertiary Amidomethyl Ester Prodrugs of Carboxylic Acid Agents , 1997, Pharmaceutical Research.
[5] H. Bundgaard,et al. Prodrugs of Peptides. 11. Chemical and Enzymatic Hydrolysis Kinetics of N-Acyloxymethyl Derivatives of a Peptide-like Bond , 1991, Pharmaceutical Research.
[6] J. Cabrita,et al. Acyloxymethyl as a Drug Protecting Group. Part 3. Tertiary O-Amidomethyl Esters of Penicillin G: Chemical Hydrolysis and Anti-Bacterial Activity , 2004, Pharmaceutical Research.
[7] K. Beaumont,et al. Design of ester prodrugs to enhance oral absorption of poorly permeable compounds: challenges to the discovery scientist. , 2003, Current drug metabolism.
[8] Scott C. Wasdo,et al. Designing for topical delivery: Prodrugs can make the difference , 2003, Medicinal research reviews.
[9] W. Roberts,et al. Correlation of aqueous and lipid solubilities with flux for prodrugs of 5-fluorouracil, theophylline, and 6-mercaptopurine: A Potts-Guy approach. , 1999, Journal of pharmaceutical sciences.
[10] R. Moreira,et al. A new direct synthesis of tertiary N-acyloxymethylamide prodrugs of carboxylic acid drugs , 1994 .
[11] K. Sloan. Prodrugs for dermal delivery , 1989 .
[12] K. Sloan,et al. Mannich base derivatives of theophylline and 5-fluorouracil: syntheses, properties and topical delivery characteristics , 1984 .