Evaluation of Gene-Based Family-Based Methods to Detect Novel Genes Associated With Familial Late Onset Alzheimer Disease
暂无分享,去创建一个
A. Goate | J. Budde | O. Harari | J. Norton | L. Ibañez | M. Fernández | Jorge L. Del-Aguila | Y. Deming | C. Cruchaga | Ncrad | J. Morris
[1] A. Fagan,et al. Polygenic risk score of sporadic late-onset Alzheimer's disease reveals a shared architecture with the familial and early-onset forms , 2018, Alzheimer's & Dementia.
[2] G. Lukács,et al. Leukoencephalopathy‐causing CLCN2 mutations are associated with impaired Cl− channel function and trafficking , 2017, The Journal of physiology.
[3] Jong Hun Kim,et al. Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease , 2017, PLoS genetics.
[4] I. Wilhelm,et al. Expression of pattern recognition receptors and activation of the non-canonical inflammasome pathway in brain pericytes , 2017, Brain, Behavior, and Immunity.
[5] Nick C Fox,et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease , 2017, Nature Genetics.
[6] Hadley Wickham,et al. ggplot2 - Elegant Graphics for Data Analysis (2nd Edition) , 2017 .
[7] Gao T. Wang,et al. Erratum: The Rare-Variant Generalized Disequilibrium Test for Association Analysis of Nuclear and Extended Pedigrees with Application to Alzheimer Disease WGS Data. , 2017, American journal of human genetics.
[8] D. Gerrelli,et al. Mutations in CPAMD8 Cause a Unique Form of Autosomal-Recessive Anterior Segment Dysgenesis , 2016, American journal of human genetics.
[9] S. Redline,et al. Increasing Generality and Power of Rare-Variant Tests by Utilizing Extended Pedigrees. , 2016, American journal of human genetics.
[10] Kevin L. Boehme,et al. Assessment of the genetic variance of late-onset Alzheimer's disease , 2016, Neurobiology of Aging.
[11] James Y. Zou. Analysis of protein-coding genetic variation in 60,706 humans , 2015, Nature.
[12] Nengjun Yi,et al. A Sequence Kernel Association Test for Dichotomous Traits in Family Samples under a Generalized Linear Mixed Model , 2015, Human Heredity.
[13] J. Becker,et al. Genetic determinants of disease progression in Alzheimer's disease. , 2014, Journal of Alzheimer's disease : JAD.
[14] Sungkyoung Choi,et al. FARVAT: a family-based rare variant association test , 2014, Bioinform..
[15] Margaret A. Pericak-Vance,et al. Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias , 2014, PLoS genetics.
[16] G. Abecasis,et al. Rare-variant association analysis: study designs and statistical tests. , 2014, American journal of human genetics.
[17] S. Rosenthal,et al. Late-Onset Alzheimer’s Disease Genes and the Potentially Implicated Pathways , 2014, Current Genetic Medicine Reports.
[18] Eden R Martin,et al. Exome sequencing of extended families with autism reveals genes shared across neurodevelopmental and neuropsychiatric disorders , 2014, Molecular Autism.
[19] Jay Shendure,et al. Rare-variant extensions of the transmission disequilibrium test: application to autism exome sequence data. , 2014, American journal of human genetics.
[20] Erick R. Scott,et al. Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease , 2013, Nature.
[21] Xihong Lin,et al. GEE‐Based SNP Set Association Test for Continuous and Discrete Traits in Family‐Based Association Studies , 2013, Genetic epidemiology.
[22] Nick C Fox,et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease , 2013, Nature Genetics.
[23] D. Schaid,et al. Multiple Genetic Variant Association Testing by Collapsing and Kernel Methods With Pedigree or Population Structured Data , 2013, Genetic epidemiology.
[24] Vladimir Makarov,et al. Family-based association tests for sequence data, and comparisons with population-based association tests , 2013, European Journal of Human Genetics.
[25] Iuliana Ionita-Laza,et al. Rare Variant Analysis for Family-Based Design , 2013, PloS one.
[26] A. Singleton,et al. Using exome sequencing to reveal mutations in TREM2 presenting as a frontotemporal dementia-like syndrome without bone involvement. , 2012, JAMA neurology.
[27] Xihong Lin,et al. Optimal tests for rare variant effects in sequencing association studies. , 2012, Biostatistics.
[28] M. Rieder,et al. Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies. , 2012, American journal of human genetics.
[29] B. Arosio,et al. NALP1/NLRP1 Genetic Variants are Associated With Alzheimer Disease , 2012, Alzheimer disease and associated disorders.
[30] M. Stephens,et al. Genome-wide Efficient Mixed Model Analysis for Association Studies , 2012, Nature Genetics.
[31] Orli G. Bahcall,et al. Rare variant association , 2012, Nature Genetics.
[32] Jennifer Williamson,et al. Rare Variants in APP, PSEN1 and PSEN2 Increase Risk for AD in Late-Onset Alzheimer's Disease Families , 2012, PloS one.
[33] Xihong Lin,et al. Rare-variant association testing for sequencing data with the sequence kernel association test. , 2011, American journal of human genetics.
[34] J. Ott,et al. Family-based designs for genome-wide association studies , 2011, Nature Reviews Genetics.
[35] Kathryn Roeder,et al. Testing for an Unusual Distribution of Rare Variants , 2011, PLoS genetics.
[36] E. Wijsman,et al. Genome-Wide Association of Familial Late-Onset Alzheimer's Disease Replicates BIN1 and CLU and Nominates CUGBP2 in Interaction with APOE , 2011, PLoS genetics.
[37] V. Bansal,et al. Statistical analysis strategies for association studies involving rare variants , 2010, Nature Reviews Genetics.
[38] Desmond J. Smith,et al. A genome-wide map of human genetic interactions inferred from radiation hybrid genotypes. , 2010, Genome research.
[39] Lee-Jen Wei,et al. Pooled Association Tests for Rare Variants in Exon-Resequencing Studies , 2010 .
[40] D. Goldstein,et al. Uncovering the roles of rare variants in common disease through whole-genome sequencing , 2010, Nature Reviews Genetics.
[41] H. Kang,et al. Variance component model to account for sample structure in genome-wide association studies , 2010, Nature Genetics.
[42] Judy H. Cho,et al. Finding the missing heritability of complex diseases , 2009, Nature.
[43] Wei-Min Chen,et al. A generalized family-based association test for dichotomous traits. , 2009, American journal of human genetics.
[44] K. Frazer,et al. Human genetic variation and its contribution to complex traits , 2009, Nature Reviews Genetics.
[45] H. Lerche,et al. Two novel CLCN2 mutations accelerating chloride channel deactivation are associated with idiopathic generalized epilepsy , 2009, Human mutation.
[46] Michael R. Johnson,et al. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. , 2009, Human molecular genetics.
[47] S. Leal,et al. Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data. , 2008, American journal of human genetics.
[48] M. Rewers,et al. Analysis of Single Nucleotide Polymorphisms Identifies Major Type 1A Diabetes Locus Telomeric of the Major Histocompatibility Complex , 2008, Diabetes.
[49] T. Thornton,et al. Case-control association testing with related individuals: a more powerful quasi-likelihood score test. , 2007, American journal of human genetics.
[50] W. Thilly,et al. A strategy to discover genes that carry multi-allelic or mono-allelic risk for common diseases: a cohort allelic sums test (CAST). , 2007, Mutation research.
[51] Michael Boehnke,et al. Efficient study designs for test of genetic association using sibship data and unrelated cases and controls. , 2006, American journal of human genetics.
[52] N. Laird,et al. Family-based designs in the age of large-scale gene-association studies , 2006, Nature Reviews Genetics.
[53] P. Sham,et al. The future of association studies: gene-based analysis and replication. , 2004, American journal of human genetics.
[54] Christoph Lange,et al. On a general class of conditional tests for family‐based association studies in genetics: the asymptotic distribution, the conditional power, and optimality considerations , 2002, Genetic epidemiology.
[55] N. Laird,et al. The family based association test method: strategies for studying general genotype–phenotype associations , 2001, European Journal of Human Genetics.
[56] T. Strachan,et al. Genomic organisation of the human chordin gene and mutation screening of candidate Cornelia de Lange syndrome genes , 1999, Human Genetics.
[57] J. Haines,et al. Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease: A Meta-analysis , 1997 .
[58] J. Haines,et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. , 1997, JAMA.
[59] W. Ewens,et al. Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). , 1993, American journal of human genetics.
[60] Tord Høivik,et al. A program , 1971 .
[61] Suzanne M. Leal,et al. The Rare-Variant Generalized Disequilibrium Test for Association Analysis of Nuclear and Extended Pedigrees with Application to Alzheimer Disease WGS Data. , 2017, American journal of human genetics.
[62] R Core Team,et al. R: A language and environment for statistical computing. , 2014 .
[63] J. Bailey,et al. Population‐based and family‐based designs to analyze rare variants in complex diseases , 2011, Genetic epidemiology.
[64] Shamil R Sunyaev,et al. Pooled association tests for rare variants in exon-resequencing studies. , 2010, American journal of human genetics.
[65] D. Balding,et al. A method for quantifying differentiation between populations at multi-allelic loci and its implications for investigating identity and paternity , 2005, Genetica.
[66] J. Pritchard,et al. Evidence for extensive transmission distortion in the human genome. , 2004, American journal of human genetics.
[67] Xin Xu,et al. Implementing a unified approach to family‐based tests of association , 2000, Genetic epidemiology.
[68] Pablo Cingolani,et al. © 2012 Landes Bioscience. Do not distribute. , 2022 .