Clostridia in cancer therapy
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[1] S. White,et al. Generation of Escherichia coli nitroreductase mutants conferring improved cell sensitization to the prodrug CB1954. , 2003, Cancer research.
[2] Ernst Wagner,et al. Tumor-targeted gene therapy: strategies for the preparation of ligand-polyethylene glycol-polyethylenimine/DNA complexes. , 2003, Journal of controlled release : official journal of the Controlled Release Society.
[3] L. Naldini,et al. In vivo targeting of tumor endothelial cells by systemic delivery of lentiviral vectors. , 2003, Human gene therapy.
[4] J. A. George,et al. Gene therapy progress and prospects: adenoviral vectors , 2003, Gene Therapy.
[5] M. Ogris,et al. Tissue-dependent factors affect gene delivery to tumors in vivo , 2003, Gene Therapy.
[6] S. Okabe,et al. Adenovirus-mediated prodrug-enzyme therapy for CEA-producing colorectal cancer cells , 2003, Journal of Cancer Research and Clinical Oncology.
[7] J. Brueggen,et al. A novel vascular endothelial growth factor-directed therapy that selectively activates cytotoxic prodrugs , 2003, British Journal of Cancer.
[8] H. Spearman,et al. Hypoxia-mediated tumour targeting , 2003, Gene Therapy.
[9] J. B. Connolly,et al. Conditionally replicating viruses in cancer therapy , 2003, Gene Therapy.
[10] M. Dobbelstein. Viruses in therapy--royal road or dead end? , 2003, Virus research.
[11] D. Kerr,et al. Immune enhancement of nitroreductase‐induced cytotoxicity: Studies using a bicistronic adenovirus vector , 2003, International journal of cancer.
[12] Gengfeng Fu,et al. Bifidobacterium adolescentis as a delivery system of endostatin for cancer gene therapy: Selective inhibitor of angiogenesis and hypoxic tumor growth , 2003, Cancer Gene Therapy.
[13] P. Wils,et al. Folate-targeted, cationic liposome-mediated gene transfer into disseminated peritoneal tumors , 2002, Gene Therapy.
[14] A. Patterson,et al. Novel chimeric gene promoters responsive to hypoxia and ionizing radiation , 2002, Gene Therapy.
[15] C. Springer,et al. A phase I trial of antibody directed enzyme prodrug therapy (ADEPT) in patients with advanced colorectal carcinoma or other CEA producing tumours , 2002, British Journal of Cancer.
[16] S. Taniguchi,et al. The genus Bifidobacterium for cancer gene therapy. , 2002, Current opinion in drug discovery & development.
[17] A. Rees,et al. A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics , 2002, Proteomics.
[18] S. Hay,et al. Satellite imagery in the study and forecast of malaria , 2002, Nature.
[19] AJ Giaccia,et al. Anticancer efficacy of systemically delivered anaerobic bacteria as gene therapy vectors targeting tumor hypoxia/necrosis , 2002, Gene Therapy.
[20] O. Bjørnstad,et al. Travelling waves and spatial hierarchies in measles epidemics , 2001, Nature.
[21] K. Kinzler,et al. Combination bacteriolytic therapy for the treatment of experimental tumors , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[22] H. McLeod,et al. Strategies for enzyme/prodrug cancer therapy. , 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.
[23] P. Lambin,et al. Insertion or Deletion of the Cheo Box Modifies Radiation Inducibility of Clostridium Promoters , 2001, Applied and Environmental Microbiology.
[24] J. Nemunaitis,et al. A phase I trial of genetically modified Salmonella typhimurium expressing cytosine deaminase (TAPET-CD, VNP20029) administered by intratumoral injection in combination with 5-fluorocytosine for patients with advanced or metastatic cancer. Protocol no: CL-017. Version: April 9, 2001. , 2001, Human gene therapy.
[25] P. Lambin,et al. Radio-responsive recA promoter significantly increases TNFα production in recombinant clostridia after 2 Gy irradiation , 2001, Gene Therapy.
[26] P. Lambin,et al. The Use of Radiation-Induced Bacterial Promoters in Anaerobic Conditions: A Means to Control Gene Expression in Clostridium-Mediated Therapy for Cancer , 2001, Radiation research.
[27] P. Lambin,et al. Specific targeting of cytosine deaminase to solid tumors by engineered Clostridium acetobutylicum , 2001, Cancer Gene Therapy.
[28] X. Luo,et al. Tumor amplified protein expression therapy: Salmonella as a tumor-selective protein delivery vector. , 2001, Oncology research.
[29] Hubert Bahl,et al. Clostridia-Biotechnology and Medical Applications , 2001 .
[30] P. Lambin,et al. Improvement of Clostridium tumour targeting vectors evaluated in rat rhabdomyosarcomas. , 2001, FEMS immunology and medical microbiology.
[31] D. Curiel,et al. Advanced generation adenoviral vectors possess augmented gene transfer efficiency based upon coxsackie adenovirus receptor-independent cellular entry capacity. , 2000, Cancer research.
[32] D. Rogers,et al. Fragile transmission cycles of tick-borne encephalitis virus may be disrupted by predicted climate change , 2000, Proceedings of the Royal Society of London. Series B: Biological Sciences.
[33] C. Balagué,et al. Replicative adenoviruses for cancer therapy , 2000, Nature Biotechnology.
[34] Y. Kano,et al. Bifidobacterium longum as a delivery system for cancer gene therapy: Selective localization and growth in hypoxic tumors , 2000, Cancer Gene Therapy.
[35] P. Lambin,et al. Stable Escherichia coli-Clostridium acetobutylicum Shuttle Vector for Secretion of Murine Tumor Necrosis Factor Alpha , 1999, Applied and Environmental Microbiology.
[36] G. Semenza. Hypoxia-inducible factor 1: master regulator of O2 homeostasis. , 1998, Current opinion in genetics & development.
[37] P. Lambin,et al. Colonisation of Clostridium in the body is restricted to hypoxic and necrotic areas of tumours. , 1998, Anaerobe.
[38] J. Pawelek,et al. Tumor-targeted Salmonella as a novel anticancer vector. , 1997, Cancer research.
[39] P. V. Zijl,et al. Anaerobic bacteria as a gene delivery system that is controlled by the tumor microenvironment , 1997, Gene Therapy.
[40] A. Giaccia,et al. Anaerobic bacteria as a delivery system for cancer gene therapy: in vitro activation of 5-fluorocytosine by genetically engineered clostridia. , 1996, Gene therapy.
[41] A. Giaccia,et al. Chemotherapeutic tumour targeting using clostridial spores. , 1995, FEMS microbiology reviews.
[42] F. Friedlos,et al. The bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954)--I. Purification and properties of a nitroreductase enzyme from Escherichia coli--a potential enzyme for antibody-directed enzyme prodrug therapy (ADEPT). , 1992, Biochemical pharmacology.
[43] K. D. Bagshawe,et al. Antibody directed enzymes revive anti-cancer prodrugs concept. , 1987, British Journal of Cancer.
[44] R. A. Malmgren,et al. Localization of the vegetative form of Clostridium tetani in mouse tumors following intravenous spore administration. , 1955, Cancer research.
[45] R. C. Parker,et al. Effect of Histolyticus Infection and Toxin on Transplantable Mouse Tumors.∗ , 1947, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[46] Adrian L. Harris,et al. Hypoxia — a key regulatory factor in tumour growth , 2002, Nature Reviews Cancer.
[47] John Mao,et al. Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma. , 2002, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[48] N. Minton,et al. Bacillus amyloliquefaciens orthologue of Bacillus subtilis ywrO encodes a nitroreductase enzyme which activates the prodrug CB 1954. , 2002, Microbiology.
[49] P. Lambin,et al. Clostridium as a tumor-specific delivery system of therapeutic proteins. , 2001, Cancer detection and prevention.
[50] R. Maxwell,et al. Combretastatins novel vascular targeting drugs for improving anti-cancer therapy. Combretastatins and conventional therapy. , 2000, Advances in experimental medicine and biology.
[51] S. Hay. An overview of remote sensing and geodesy for epidemiology and public health application. , 2000, Advances in parasitology.
[52] R. Maxwell,et al. Combretastatins Novel Vascular targeting Drugs for Improving Anticancer therapy , 2000 .
[53] Samuel I. Miller,et al. Lipid A mutant Salmonella with suppressed virulence and TNFα induction retain tumor-targeting in vivo , 1999, Nature Biotechnology.
[54] Arnold L. Demain,et al. Manual of Industrial Microbiology and Biotechnology , 1986 .
[55] A. Polak,et al. Metabolic studies with 5-fluorocytosine-6-14C in mouse, rat, rabbit, dog and man. , 1976, Chemotherapy.