Folate in Health and Disease

Folate Chemistry and Metabolism, Barry Shane Folate Bioavailability, Helene McNulty and Kristina Pentieva Folate Biochemical Pathways and Their Regulation, Patrick J. Stover Genetic Variation: Effect on Folate Metabolism and Health, Karen E. Christensen and Rima Rozen Folate in Pregnancy and Lactation, Tsunenobu Tamura, Mary Frances Picciano, and Michelle Kay McGuire Folate Status and Birth Defect Risk: Epidemiological Perspective, Charlotte A. Hobbs, Gary M. Shaw, Martha M. Werler, and Bridget Mosley Folate-Related Birth Defects: Embryonic Consequences of Abnormal Folate Transport and Metabolism, Deeann Wallis, Johnathan L. Ballard, Gary M. Shaw, Edward J. Lammer, and Richard H. Finnell Folic Acid Fortification: Neural Tube Defect Risk Reduction-A Global Perspective, Robert J. Berry, Joseph Mulinare, and Heather C. Hamner Folate and Cancer: Epidemiological Perspective, Jia Chen, Xinran Xu, Amy Liu, and Cornelia M. Ulrich Folate and Carcinogenesis: Basic Mechanisms, Eric Ciappio and Joel B. Mason Folate and Vascular Disease: Epidemiological Perspective, Sari R. Kalin and Eric B. Rimm Folate and Vascular Disease: Basic Mechanisms, Luciana Hannibal, Alla V. Glushchenko, and Donald W. Jacobsen Folate and Neurological Function: Epidemiological Perspective, Martha Savaria Morris and Paul F. Jacques Folate and Neurological Disease: Basic Mechanisms, Teodoro Bottiglieri and Edward Reynolds Folate-Vitamin B12 Interrelationships: Links to Disease Risk, Anne M. Molloy Clinical Folate Deficiency, Sally P. Stabler Influence of Alcohol on Folate Status and Methionine Metabolism in Relation to Alcoholic Liver Disease, Charles H. Halsted, Valentina Medici, and Farah Esfandiari Folate and Choline Inter-relationships: Metabolic and Potential Health Implications, Marie A. Caudill Folate: Recommended Intakes, Consumption, and Status, Gail P. A. Kauwell, Megan L. Diaz, Quanhe Yang, and Lynn B. Bailey Kinetics of Folate and One-Carbon Metabolism, Jesse F. Gregory III, Vanessa R. da Silva, and Yvonne Lamers Folate Analytical Methodology, Christine M. Pfeiffer, Zia Fazili, and Mindy Zhang Index

[1]  B. Chabner,et al.  Drug Actions Interactions & Reactions , 1973, The New England journal of medicine.

[2]  I. Rosenberg,et al.  Bacterially synthesized folate in rat large intestine is incorporated into host tissue folyl polyglutamates. , 1991, The Journal of nutrition.

[3]  B. Shane,et al.  Mammalian folylpoly-gamma-glutamate synthetase. 3. Specificity for folate analogues. , 1987, Biochemistry.

[4]  I. Chanarin,et al.  Cobalamin and folate: recent developments. , 1992, Journal of clinical pathology.

[5]  B. Shane,et al.  Mammalian folylpoly-gamma-glutamate synthetase. 4. In vitro and in vivo metabolism of folates and analogues and regulation of folate homeostasis. , 1987, Biochemistry.

[6]  E. Stokstad,et al.  Mammalian methylenetetrahydrofolate reductase. Partial purification, properties, and inhibition by S-adenosylmethionine. , 1971, Biochimica et biophysica acta.

[7]  J. Bertino,et al.  Enzymatic synthesis of folylpolyglutamates. Characterization of the reaction and its products. , 1980, The Journal of biological chemistry.

[8]  D. Cesar,et al.  In vitro metabolism of 5,8-dideazafolates and 5,8-dideazaisofolates by mammalian folylpoly-gamma-glutamate synthetase. , 1991, Biochemical pharmacology.

[9]  A. Wittwer,et al.  Identification of the folate-binding proteins of rat liver mitochondria as dimethylglycine dehydrogenase and sarcosine dehydrogenase. Purification and folate-binding characteristics. , 1981, The Journal of biological chemistry.

[10]  B. Elsenhans,et al.  Isolation and characterization of pteroylpolyglutamate hydrolase from rat intestinal mucosa. , 1984, The Journal of biological chemistry.

[11]  D. Priest,et al.  Comparison of folylpolyglutamate hydrolases of mouse liver, kidney, muscle and brain , 1982, Molecular and Cellular Biochemistry.

[12]  B. Shane,et al.  Mammalian folylpoly-gamma-glutamate synthetase. 1. Purification and general properties of the hog liver enzyme. , 1987, Biochemistry.

[13]  D. Weir,et al.  The elucidation of the mechanism of folate catabolism in the rat. , 1976, Biochemical and biophysical research communications.

[14]  L. Bailey,et al.  In vivo folate kinetics during chronic supplementation of human subjects with deuterium-labeled folic acid. , 1992, The Journal of nutrition.

[15]  B. Shane,et al.  Mammalian folylpoly-gamma-glutamate synthetase. 2. Substrate specificity and kinetic properties. , 1987, Biochemistry.

[16]  S. Weitman,et al.  Accumulation of 5‐methyltetrahydrofolic acid and folylpolyglutamate synthetase expression by mitogen stimulated human lymphocytes , 1993, British journal of haematology.

[17]  A. Hoffbrand,et al.  Correction of the DNA synthesis defect in vitamin B12 deficiency by tetrahydrofolate: evidence in favour of the methyl‐folate trap hypothesis as the cause of megaloblastic anaemia in vitamin B12 deficiency , 1993, British journal of haematology.

[18]  M. Vuchich,et al.  Inhibition of gamma-glutamyl hydrolases in human cells by 2-mercaptomethylglutaric acid. , 1987, Biochemical and biophysical research communications.

[19]  W. M. Williams,et al.  Renal tubular transport of folic acid and methotrexate in the monkey. , 1982, The American journal of physiology.

[20]  F. Sirotnak,et al.  Similar differential for total polyglutamylation and cytotoxicity among various folate analogues in human and murine tumor cells in vitro. , 1985, Cancer research.

[21]  T. D. Collins,et al.  Effects of acute ethanol on urinary excretion of 5-methyltetrahydrofolic acid and folate derivatives in the rat. , 1989, The Journal of nutrition.

[22]  A. Halligan,et al.  Accelerated folate breakdown in pregnancy , 1993, The Lancet.

[23]  J. Gregory.  Chemical and nutritional aspects of folate research: analytical procedures, methods of folate synthesis, stability, and bioavailability of dietary folates. , 1989, Advances in food and nutrition research.

[24]  T. T. Wang,et al.  Pteroylpolyglutamate hydrolase from human jejunal brush borders. Purification and characterization. , 1986, The Journal of biological chemistry.

[25]  J. Bertino,et al.  Decreased folylpolyglutamate synthetase activity as a mechanism of methotrexate resistance in CCRF-CEM human leukemia sublines. , 1991, The Journal of biological chemistry.

[26]  A. Admon,et al.  Expression cloning of a human cDNA encoding folylpoly(gamma-glutamate) synthetase and determination of its primary structure. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[27]  R. Cook,et al.  Glycine N-methyltransferase is a folate binding protein of rat liver cytosol. , 1984, Proceedings of the National Academy of Sciences of the United States of America.

[28]  T. T. Wang,et al.  Intracellular pteroylpolyglutamate hydrolase from human jejunal mucosa. Isolation and characterization. , 1986, The Journal of biological chemistry.

[29]  F. Carone,et al.  Renal folate absorption and the kidney folate binding protein. II. Microinfusion studies. , 1987, The American journal of physiology.

[30]  D. Cohen,et al.  Folic acid and B12 in autism and neuropsychiatric disturbances of childhood. , 1981, Journal of the American Academy of Child Psychiatry.

[31]  P. Nixon,et al.  An inverse relationship of rat liver folate polyglutamate chain length to nutritional folate sufficiency. , 1980, Biochimica et biophysica acta.

[32]  R. Cook,et al.  Inhibition of glycine N-methyltransferase activity by folate derivatives: implications for regulation of methyl group metabolism. , 1985, Biochemical and biophysical research communications.

[33]  H. Sauberlich.  Bioavailability of vitamins. , 1985, Progress in food & nutrition science.

[34]  Ying Wang,et al.  Acquisition of Resistance to Antifolates Caused by Enhanced γ-Glutamyl Hydrolase Activity , 1993 .

[35]  R. Moran,et al.  Mammalian folyl polyglutamate synthetase: partial purification and properties of the mouse liver enzyme. , 1984, Biochemistry.

[36]  J. Galivan,et al.  Secretion of γ-Glutamyl Hydrolase in Vitro , 1991 .

[37]  C. Wagner,et al.  Effect of folacin deficiency on folacin-binding proteins in the rat. , 1977, The Journal of nutrition.