Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells

[1]  Rudolf Jaenisch,et al.  Reprogramming factor stoichiometry influences the epigenetic state and biological properties of induced pluripotent stem cells. , 2011, Cell stem cell.

[2]  G. Pan,et al.  The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner. , 2011, Cell stem cell.

[3]  S. Gaines,et al.  The Mouse , 2011 .

[4]  Mitsugu Sekimoto,et al.  Reprogramming of mouse and human cells to pluripotency using mature microRNAs. , 2011, Cell stem cell.

[5]  K. Hochedlinger,et al.  Harnessing the potential of induced pluripotent stem cells for regenerative medicine , 2011, Nature Cell Biology.

[6]  Xiu-Jie Wang,et al.  iPS cells generated without c-Myc have active Dlk1-Dio3 region and are capable of producing full-term mice through tetraploid complementation , 2011, Cell Research.

[7]  Shaorong Gao,et al.  Viable mice produced from three-factor induced pluripotent stem (iPS) cells through tetraploid complementation , 2011, Cell Research.

[8]  Michael J. Ziller,et al.  Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines , 2011, Cell.

[9]  K. Hochedlinger,et al.  Induced pluripotency: history, mechanisms, and applications. , 2010, Genes & development.

[10]  P. Laird,et al.  Vitamin C Promotes Widespread Yet Specific DNA Demethylation of the Epigenome in Human Embryonic Stem Cells , 2010, Stem cells.

[11]  R. Bronson,et al.  Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene , 2010 .

[12]  Tomohiro Kono,et al.  Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells , 2010, Nature.

[13]  Wei Li,et al.  Activation of the Imprinted Dlk1-Dio3 Region Correlates with Pluripotency Levels of Mouse Stem Cells , 2010, The Journal of Biological Chemistry.

[14]  Albert Jeltsch,et al.  Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail , 2010, Nucleic acids research.

[15]  H. Redl,et al.  Vitamin C enhances the generation of mouse and human induced pluripotent stem cells. , 2010, Cell stem cell.

[16]  M. Shirakawa,et al.  Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX–DNMT3–DNMT3L domain , 2009, EMBO reports.

[17]  Cole Trapnell,et al.  Ultrafast and memory-efficient alignment of short DNA sequences to the human genome , 2009, Genome Biology.

[18]  K. Hochedlinger,et al.  Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette , 2009, Stem cells.

[19]  P. Park,et al.  Design and analysis of ChIP-seq experiments for DNA-binding proteins , 2008, Nature Biotechnology.

[20]  M. Araúzo-Bravo,et al.  Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors , 2008, Nature.

[21]  A. Ferguson-Smith,et al.  Genomic imprinting at the mammalian Dlk1-Dio3 domain. , 2008, Trends in genetics : TIG.

[22]  Marius Wernig,et al.  Direct Reprogramming of Terminally Differentiated Mature B Lymphocytes to Pluripotency , 2008, Cell.

[23]  K. Hochedlinger,et al.  Defining molecular cornerstones during fibroblast to iPS cell reprogramming in mouse. , 2008, Cell stem cell.

[24]  Y. Kohara,et al.  Role of the Dnmt3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse. , 2007, Human molecular genetics.

[25]  M. Ramalho-Santos,et al.  Generation of induced pluripotent stem cells in the absence of drug selection. , 2007, Cell stem cell.

[26]  T. Mikkelsen,et al.  Genome-wide maps of chromatin state in pluripotent and lineage-committed cells , 2007, Nature.

[27]  S. Yamanaka,et al.  Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.

[28]  S. Orkin,et al.  Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival. , 2004, Genes & development.

[29]  T. Bestor,et al.  Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L , 2004, Nature.

[30]  E. Li,et al.  Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting , 2004, Nature.

[31]  K. Coser,et al.  Global analysis of ligand sensitivity of estrogen inducible and suppressible genes in MCF7/BUS breast cancer cells by DNA microarray , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[32]  R. Jaenisch,et al.  Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[33]  G. Wu,et al.  Ig gene rearrangements on individual alleles of Abelson murine leukemia cell lines from (C57BL/6 x BALB/c) F1 fetal livers. , 1991, Journal of immunology.

[34]  J. Rossant,et al.  Embryonic stem cells alone are able to support fetal development in the mouse. , 1990, Development.

[35]  K. Hochedlinger,et al.  A reprogrammable mouse strain from gene-targeted embryonic stem cells , 2010, Nature Methods.