High pressure-induced changes in milk proteins and possible applications in dairy technology

This paper reviews the newest information on the effects of high pressure (HP) on whey proteins, caseins and milk enzymes, and discusses their influence on milk properties. HP treatments cause substantial modification to milk proteins and to the mineral balance of milk. Casein micelles disaggregate into smaller particles or aggregate, depending the intensity and the temperature of the HP treatment. Whey proteins are denatured, possibly interacting with the remnants of the casein micelles, and give aggregated forms different from those produced by heat treatment. These events influence rennet coagulation properties of milk, with micellar disintegration favoring coagulation and whey protein denaturation hindering the aggregation of renneted micelles and enhancing cheese yield. HP treatment of milk favors acid coagulation and produces acid gels whose structure is greatly determined by the different micellar sizes attainable and the degree of whey protein denaturation. Milk gels can also be formed from concentrated milk under HP, providing new structures inaccessible via conventional methods.

[1]  M. Buffa,et al.  Proteolysis in goat cheese made from raw, pasteurized or pressure-treated milk☆ , 2002 .

[2]  S. Anema,et al.  High-pressure-induced interactions between milk fat globule membrane proteins and skim milk proteins in whole milk. , 2004, Journal of dairy science.

[3]  P. Fox,et al.  High pressure-induced denaturation of α-lactalbumin and β-lactoglobulin in bovine milk and whey: a possible mechanism , 2004, Journal of Dairy Research.

[4]  P. Fox,et al.  High-pressure-induced changes in the rennet coagulation properties of bovine milk , 2005 .

[5]  P. Fox,et al.  Properties of casein micelles in high pressure-treated bovine milk , 2004 .

[6]  W. Buchheim,et al.  High pressure effects on the colloidal calcium phosphate and the structural integrity of micellar casein in milk. II. Kinetics of the casein micelle disintegration and protein interactions in milk , 1998 .

[7]  S. Shimizu,et al.  Dissociation and reassociation of enzyme-treated caseins under high pressure , 1989, Journal of Dairy Research.

[8]  R. López-Fandiño,et al.  Use of high-pressure-treated milk for the production of reduced-fat cheese , 2000 .

[9]  A. Law Effects of heat treatment and acidification on the dissociation of bovine casein micelles , 1996, Journal of Dairy Research.

[10]  M. Buffa,et al.  Changes in organic acids during ripening of cheeses made from raw, pasteurized or high-pressure-treated goats’ milk , 2004 .

[11]  H. Ramaswamy,et al.  Effect of high-pressure treatment of milk on lipase and γ-glutamyl transferase activity , 2004 .

[12]  J. Hardy,et al.  Study of Acid and Rennet Coagulation of High Pressurized Milk , 1994 .

[13]  C. Hubbard,et al.  Characterisation of pressure‐treated skimmed milk powder dispersions: application of NMR spectroscopy , 2002 .

[14]  Cheng Tet Teo,et al.  Acid-Induced Dissociation of Casein Micelles in Milk: Effects of Heat Treatment , 1996 .

[15]  F. Remeuf,et al.  The Effect of Heating on Physicochemical and Renneting Properties of Milk: A Comparison between Caprine, Ovine and Bovine Milk , 1998 .

[16]  Jordi Saldo,et al.  Applications of high-hydrostatic pressure on milk and dairy products: a review , 2002 .

[17]  G. Barbosa‐Cánovas,et al.  Flow and Viscoelastic Properties of Concentrated Milk Treated by High Hydrostatic Pressure , 1998 .

[18]  S. Anema,et al.  EFFECT OF PH ON THE TURBIDITY OF PRESSURE-TREATED CALCIUM CASEINATE SUSPENSIONS AND SKIM MILK , 1997 .

[19]  P. Fox,et al.  Influence of high pressure treatment on the acidification of bovine milk by lactic acid bacteria , 2004 .

[20]  E. Dumay,et al.  High Pressure Promotes β-Lactoglobulin Aggregation through SH/S−S Interchange Reactions , 1997 .

[21]  A. Kelly,et al.  Barostability of milk plasmin activity , 2000 .

[22]  F. Mariette,et al.  Acidification of pressure-treated milk , 1997 .

[23]  M. Buffa,et al.  Changes in textural, microstructural, and colour characteristics during ripening of cheeses made from raw, pasteurized or high-pressure-treated goats’ milk , 2001 .

[24]  P. Fox,et al.  Effects of high pressure on some constituents and properties of buffalo milk. , 2005, The Journal of dairy research.

[25]  M. Hendrickx,et al.  Effect of temperature and/or pressure on lactoperoxidase activity in bovine milk and acid whey , 2001, Journal of Dairy Research.

[26]  Skelte G. Anema,et al.  Particle size changes and casein solubilisation in high-pressure-treated skim milk , 2005 .

[27]  R. López-Fandiño,et al.  Microbiological and chemical changes in high-pressure-treated milk during refrigerated storage. , 1998, Journal of food protection.

[28]  P. Fox,et al.  High pressure-induced changes in the creaming properties of bovine milk , 2003 .

[29]  M. Hendrickx,et al.  Review: are intrinsic TTIs for thermally processed milk applicable for high-pressure processing assessment? , 2003 .

[30]  D. Knorr,et al.  Pressure Induced Inactivation of Selected Food Enzymes , 1996 .

[31]  Indrawati,et al.  High pressure thermal inactivation kinetics of a plasmin system. , 2004, Journal of dairy science.

[32]  D. E. Johnston,et al.  Acidification of high pressure treated milk: The role of whey protein denaturation , 2002 .

[33]  P. Fox,et al.  Heat and ethanol stabilities of high-pressure-treated bovine milk , 2004 .

[34]  H. Deeth,et al.  High pressure processing of milk and dairy products , 1999 .

[35]  M. Capellas,et al.  Physical properties of yogurt prepared from pressure-treated concentrated or fortified milks , 2003 .

[36]  G. Barbosa‐Cánovas,et al.  Low-fat set yogurt made from milk subjected to combinations of high hydrostatic pressure and thermal processing. , 2003, Journal of dairy science.

[37]  A. Law,et al.  Comparison of the Effects of High-Pressure Treatments and Heat Pasteurization on the Whey Proteins in Goat's Milk , 1997 .

[38]  François Mariette,et al.  Combined effects of temperature and high-pressure treatments on physicochemical characteristics of skim milk , 1997 .

[39]  S. Abbasi,et al.  Influence of High-pressure Treatment on Gelation of Skim Milk Powder+Low Methoxyl Pectin Dispersions , 2002 .

[40]  J. Bouvier,et al.  Effect of ultra-high hydrostatic pressure on hydrosoluble vitamins , 1999 .

[41]  P. Fox,et al.  Plasmin activity and proteolysis in high pressure-treated bovine milk , 2004 .

[42]  Alan L. Kelly,et al.  Effects of high pressure on constituents and properties of milk , 2002 .

[43]  C. Holt,et al.  Effects of colloidal calcium phosphate content and free calcium ion concentration in the milk serum on the dissociation of bovine casein micelles , 1986, Journal of Dairy Research.

[44]  P. Fox,et al.  Dissociation of caseins in high pressure-treated bovine milk , 2004 .

[45]  J. Hinrichs,et al.  Kinetics of combined thermal and pressure-induced whey protein denaturation in bovine skim milk , 2005 .

[46]  P. Fox,et al.  Effects of cycled high pressure treatment on casein micelles and whey proteins in bovine milk , 2004 .

[47]  Thom Huppertz,et al.  High pressure treatment of bovine milk: effects on casein micelles and whey proteins. , 2004, The Journal of dairy research.

[48]  Brendan T. O’Kennedy,et al.  A rheological study of acid-set "simulated yogurt milk" gels prepared from heat- or pressure-treated milk proteins , 2001 .

[49]  A. D. Jones,et al.  Mechanism of pressure-induced gelation of milk. , 2001, Journal of agricultural and food chemistry.

[50]  Gustavo V. Barbosa-Cánovas,et al.  Yield Stress and Microstructure of Set Yogurt Made from High Hydrostatic Pressure-Treated Full Fat Milk , 2002 .

[51]  W. Buchheim,et al.  Coagulation of skim milk under high hydrostatic pressure with acidification by glucono-δ-lactone , 1999 .

[52]  R. López-Fandiño,et al.  The Effects of High Pressure on Whey Protein Denaturation and Cheese-Making Properties of Raw Milk , 1996 .

[53]  B. Guamis,et al.  Ripening Profiles of Goat Cheese Produced from Milk Treated with High Pressure , 1999 .

[54]  D. E. Johnston,et al.  Ethanol stability and chymosin-induced coagulation behaviour of high pressure treated milk , 2002 .

[55]  P. Fox,et al.  Effects of high pressure treatment on the rennet coagulation and cheese-making properties of heated milk , 2005 .

[56]  B. Guamis,et al.  Comparison of the Effects of High Pressure and Thermal Treatments on the Casein Micelles in Goat's Milk , 1998 .

[57]  S. Anema,et al.  EFFECT OF HIGH HYDROSTATIC PRESSURE ON CA-CASEINATE SYSTEMS , 1996 .

[58]  V. Casal,et al.  Effects of high pressure and heat treatment on the mineral balance of goats' milk , 1999, Journal of Dairy Research.

[59]  R. López-Fandiño,et al.  Micellar changes induced by high pressure. influence in the proteolytic activity and organoleptic properties of milk. , 2000, Journal of dairy science.

[60]  D. McMahon,et al.  Aseptic Rennet Coagulation of Ultra-High Temperature Processed Milk Concentrates , 1996 .

[61]  R. López-Fandiño,et al.  Rennet Coagulation of Milk Subjected to High Pressures , 1997 .

[62]  M. Capellas,et al.  Effect of High Pressure on the Consumer Liking and Preference of Yoghurt , 2002 .

[63]  A. V. Van Loey,et al.  Mathematical models for combined high pressure and thermal plasmin inactivation kinetics in two model systems. , 2004, Journal of dairy science.

[64]  P. Fox,et al.  Effects of high pressure treatment on the yield of cheese curd from bovine milk , 2004 .

[65]  G. I. Imafidon,et al.  Solvation of Rennet Curd from High-Heat-Treated Milk Influenced by Acid Type and pH , 1996 .

[66]  R. López-Fandiño,et al.  Effects of High Pressures Combined with Moderate Temperatures on the Rennet Coagulation Properties of Milk , 1998 .

[67]  Thomas Henle,et al.  Rheological properties of acid gels prepared from pressure- and transglutaminase-treated skim milk , 2005 .

[68]  A. Kelly,et al.  Plasmin activity, β-lactoglobulin denaturation and proteolysis in high pressure treated milk , 2000 .

[69]  P. Manoj,et al.  Comparison of heat and pressure treatments of skim milk, fortified with whey protein concentrate, for set yogurt preparation: effects on milk proteins and gel structure , 2000, Journal of Dairy Research.

[70]  R. López-Fandiño,et al.  Plasmin activity in pressurized milk. , 2003, Journal of dairy science.

[71]  V. Ferragut,et al.  High-pressure treatment of milk: effects on casein micelle structure and on enzymic coagulation. , 2000, The Journal of dairy research.

[72]  J. Girardet,et al.  Isolation and Characterization of Copolymers of β-Lactoglobulin, α-Lactalbumin, κ-Casein, and αs1-Casein Generated by Pressurization and Thermal Treatment of Raw Milk , 2004 .

[73]  R. López-Fandiño Functional Improvement of Milk Whey Proteins Induced by High Hydrostatic Pressure , 2006, Critical reviews in food science and nutrition.

[74]  B. Guamis,et al.  Properties of yogurts made from whole ewe's milk treated by high hydrostatic pressure. , 2000 .

[75]  J. Hinrichs,et al.  Firmness of pressure-induced casein and whey protein gels modulated by holding time and rate of pressure release , 2003 .

[76]  T. Aoki,et al.  Dissociation during dialysis of casein aggregates cross-linked by colloidal calcium phosphate in bovine casein micelles , 1988, Journal of Dairy Research.

[77]  B. Guamis,et al.  Influence of pressurization on goat milk and cheese composition and yield , 1999 .

[78]  E. Needs High Pressure Processing of Dairy Products , 2001 .

[79]  Eliane Dumay,et al.  Pressurisation of raw skim milk and of a dispersion of phosphocaseinate at 9°C or 20°C: effects on casein micelle size distribution , 2004 .

[80]  G. Barbosa‐Cánovas,et al.  High Pressure Treatment of Milk and Effects on Microbiological and Sensory Quality of Cheddar Cheese , 1997 .

[81]  D. E. Johnston,et al.  Properties of acid-set gels prepared from high pressure treated skim milk , 1993 .

[82]  H. Ramaswamy,et al.  Effect of high pressure processing on rennet coagulation properties of milk , 2003 .

[83]  T. Haertlé,et al.  Baric Oligomerization in a-Lactalbumin/-Lactoglobulin Mixtures , 1997 .

[84]  B. Guamis,et al.  High Hydrostatic Pressure Effects on Color and Milk‐Fat Globule of Ewe's Milk , 2001 .

[85]  B. Guamis,et al.  Lipolysis in cheese made from raw, pasteurized or high-pressure-treated goats’ milk , 2001 .

[86]  D. E. Johnston,et al.  Effects of high hydrostatic pressure on milk , 1992 .

[87]  A. Olano,et al.  Influence of pH on the effects of high pressure on milk proteins. , 2000 .

[88]  M. Buffa,et al.  Changes in water binding during ripening of cheeses made from raw, pasteurized or high-pressure-treated goat milk , 2003 .

[89]  D. Clark,et al.  Pressure effects on intra- and intermolecular interactions within proteins. , 2002, Biochimica et biophysica acta.

[90]  R. López-Fandiño,et al.  Cheese-making properties of ovine and caprine milks submitted to high pressures , 1998 .

[91]  Rodney J. Brown,et al.  Plasmin in milk and dairy products: an update , 1996 .

[92]  F. Gaucheron,et al.  Buffering capacity of dairy products , 2005 .

[93]  H. Ramaswamy,et al.  Water-holding capacity and gel strength of rennet curd as affected by high-pressure treatment of milk. , 2000 .

[94]  G. Brûlé,et al.  High pressure-induced gel formation of milk and whey concentrates , 1998 .

[95]  R. López-Fandiño,et al.  Distribution of minerals and proteins between the soluble and colloidal phases of pressurized milks from different species , 1998, Journal of Dairy Research.

[96]  C. V. Morr,et al.  High pressure effects on the colloidal calcium phosphate and the structural integrity of micellar casein milk. Part 1. High pressure dissolution of colloidal calcium phosphate in heated milk systems. , 1997, Die Nahrung.

[97]  S. Sandra,et al.  The use of high-pressure processing in the production of queso fresco cheese , 2004 .

[98]  I. Sierra,et al.  Effect of high pressure on the vitamin B1 and B6 content of milk. , 2000 .

[99]  S. Abbasi,et al.  Gelation of iota-carrageenan and micellar casein mixtures under high hydrostatic pressure. , 2004, Journal of agricultural and food chemistry.

[100]  S. Abbasi,et al.  Influence of sugars on high-pressure induced gelation of skim milk dispersions , 2001 .

[101]  C. Balny,et al.  High-pressure as a tool to study some proteins’ properties: conformational modification, activity and oligomeric dissociation , 2002 .

[102]  S. Abbasi,et al.  High-pressure-induced rheological changes of low-methoxyl pectin plus micellar casein mixtures. , 2002, Journal of Agricultural and Food Chemistry.

[103]  M. Hendrickx,et al.  Combined pressure-temperature inactivation of alkaline phosphatase in bovine milk : A kinetic study , 2000 .

[104]  R Andrew Wilbey,et al.  High pressure processing of milk‐the first 100 years in the development of a new technology , 1999 .