022. Granular cell tumor of the lung

Background Granular cell tumor, also known as granular cell myoblastoma, is an uncommon benign tumor with female predisposition, that involves any part of the oral cavity, but the tongue is the most common site. It is considered to be of mesenchymal origin (myoblastic), but at present, the tumor is believed to derive from Schwann cells, and the granularity of the cytoplasm may be associated with accumulation of lysosomes. Cases of granular cell tumors of the lung/ tracheobronchial tree are extremely rare (6-10% of all the granular cell tumors, 0.2% of the lung neoplasms).