Single-cell gene expression reveals a landscape of regulatory T cell phenotypes shaped by the TCR
暂无分享,去创建一个
Allon M Klein | Allon M. Klein | David Zemmour | Christophe Benoist | Evgeny Kiner | C. Benoist | R. Zilionis | D. Mathis | D. Zemmour | Evgeny Kiner | Diane Mathis | Rapolas Zilionis
[1] Deepali V. Sawant,et al. Once a Treg, always a Treg? , 2014, Immunological reviews.
[2] M. Kleinewietfeld,et al. CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset. , 2005, Blood.
[3] D. Vignali,et al. How regulatory T cells work , 2008, Nature Reviews Immunology.
[4] S. Nutt,et al. Differentiation and function of Foxp3(+) effector regulatory T cells. , 2013, Trends in immunology.
[5] A. Regev,et al. Revealing the vectors of cellular identity with single-cell genomics , 2016, Nature Biotechnology.
[6] B. Nogrady. Q&A: Declan Murphy , 2015, Nature.
[7] Michael Q. Zhang,et al. Novel Foxo1-dependent transcriptional programs control Treg cell function , 2012, Nature.
[8] I. Amit,et al. Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types , 2014, Science.
[9] Ronald N. Germain,et al. Immune homeostasis enforced by co-localized effector and regulatory T cells , 2015, Nature.
[10] Mikhail Shugay,et al. MiXCR: software for comprehensive adaptive immunity profiling , 2015, Nature Methods.
[11] A. Rudensky,et al. T cell receptor signalling in the control of regulatory T cell differentiation and function , 2016, Nature Reviews Immunology.
[12] A. Rudensky,et al. A function for interleukin 2 in Foxp3-expressing regulatory T cells , 2005, Nature Immunology.
[13] Pablo Tamayo,et al. Compendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation. , 2016, Immunity.
[14] Shane J. Neph,et al. Foxp3 Exploits a Pre-Existent Enhancer Landscape for Regulatory T Cell Lineage Specification , 2012, Cell.
[15] D. Campbell,et al. Phenotypical and functional specialization of FOXP3+ regulatory T cells , 2011, Nature Reviews Immunology.
[16] David Zemmour,et al. Aire controls gene expression in the thymic epithelium with ordered stochasticity , 2015, Nature Immunology.
[17] S. Singhal,et al. Inhibition of p300 impairs Foxp3+ T-regulatory cell function and promotes anti-tumor immunity , 2013, Nature Medicine.
[18] C. Leslie,et al. A mechanism for expansion of regulatory T cell repertoire and its role in self tolerance , 2015, Nature.
[19] Christophe Benoist,et al. Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. , 2007, Immunity.
[20] A. Rudensky,et al. Regulatory T cells: mechanisms of differentiation and function. , 2012, Annual review of immunology.
[21] Christophe Benoist,et al. Stability of the Regulatory T Cell Lineage in Vivo , 2010, Science.
[22] J. Bluestone,et al. Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo , 2009, Nature Immunology.
[23] H. Weiner,et al. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells , 2006, Nature.
[24] T. Hashimshony,et al. CEL-Seq: single-cell RNA-Seq by multiplexed linear amplification. , 2012, Cell reports.
[25] B. Stranger,et al. Interindividual variation in human T regulatory cells , 2014, Proceedings of the National Academy of Sciences.
[26] A. Rudensky,et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[27] Ming O. Li,et al. Transcriptional control of regulatory T cell development and function , 2013, Trends in Immunology.
[28] Scott J. Tebbutt,et al. A Regulatory T-Cell Gene Signature Is a Specific and Sensitive Biomarker to Identify Children With New-Onset Type 1 Diabetes , 2016, Diabetes.
[29] Rona S. Gertner,et al. Single cell RNA Seq reveals dynamic paracrine control of cellular variation , 2014, Nature.
[30] R. Balderas,et al. Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation , 2011, Nature Immunology.
[31] T. Holderried,et al. Stable inhibitory activity of regulatory T cells requires the transcription factor Helios , 2015, Science.
[32] D. Campbell,et al. CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets , 2014, The Journal of experimental medicine.
[33] Tim F. Rayner,et al. Foxp3+ follicular regulatory T cells control T follicular helper cells and the germinal center response , 2011, Nature Medicine.
[34] Allon M. Klein,et al. Droplet Barcoding for Single-Cell Transcriptomics Applied to Embryonic Stem Cells , 2015, Cell.
[35] Geoffrey E. Hinton,et al. Visualizing Data using t-SNE , 2008 .
[36] Daniel J. Campbell,et al. T-bet controls regulatory T cell homeostasis and function during type-1 inflammation , 2009, Nature Immunology.
[37] A. Vandenbon,et al. Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment , 2017, Nature Immunology.
[38] Herman Waldmann,et al. Plasticity of Foxp3(+) T cells reflects promiscuous Foxp3 expression in conventional T cells but not reprogramming of regulatory T cells. , 2012, Immunity.
[39] C. Benoist,et al. Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity , 2017, Proceedings of the National Academy of Sciences.
[40] Nicole R. Cunningham,et al. T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse , 2011, The Journal of experimental medicine.
[41] Cole Trapnell,et al. TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions , 2013, Genome Biology.
[42] A. Rudensky,et al. Homeostasis and anergy of CD4+CD25+ suppressor T cells in vivo , 2002, Nature Immunology.
[43] Liza Konnikova,et al. Individual intestinal symbionts induce a distinct population of RORγ+ regulatory T cells , 2015, Science.
[44] Allon M. Klein,et al. Single-cell barcoding and sequencing using droplet microfluidics , 2016, Nature Protocols.
[45] T. Nomura,et al. Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. , 2009, Immunity.
[46] Mark M. Davis,et al. Restricted islet-cell reactive T cell repertoire of early pancreatic islet infiltrates in NOD mice , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[47] B. Malissen,et al. Early T cell activation: integrating biochemical, structural, and biophysical cues. , 2015, Annual review of immunology.
[48] A. Rudensky,et al. Continuous requirement for the T cell receptor for regulatory T cell function , 2014, Nature Immunology.
[49] A. Sharpe,et al. T follicular regulatory cells , 2016, Immunological reviews.
[50] W. Huber,et al. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.
[51] C. Benoist,et al. A Special Population of Regulatory T Cells Potentiates Muscle Repair , 2013, Cell.
[52] Hans Clevers,et al. Single-cell messenger RNA sequencing reveals rare intestinal cell types , 2015, Nature.
[53] C. Hsieh,et al. Peripheral education of the immune system by colonic commensal microbiota , 2011, Nature.
[54] A. Weiss,et al. Endogenous Nur77 Is a Specific Indicator of Antigen Receptor Signaling in Human T and B Cells , 2017, The Journal of Immunology.
[55] C. Benoist,et al. Convergent and divergent effects of costimulatory molecules in conventional and regulatory CD4+ T cells , 2012, Proceedings of the National Academy of Sciences.
[56] M. Farrar,et al. Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells , 2014, Nature Immunology.
[57] A. Rudensky,et al. Differentiation of regulatory Foxp3+ T cells in the thymic cortex , 2008, Proceedings of the National Academy of Sciences.
[58] Christian Hennig,et al. Cluster-wise assessment of cluster stability , 2007, Comput. Stat. Data Anal..
[59] W. Shi,et al. The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells , 2011, Nature Immunology.