Low-level analysis of oligonucleotide expression arrays

High-density oligonucleotide microarray technology has been widely used in many biomedical research areas (Lockhart et al., 1996; Lipshutz et al., 1999). This section gives a brief introduction of oligonucleotide expression microarrays and low-level microarray data analysis, including feature extraction, normalization, and expression index calculation. Keywords: high-density oligonucleotide microarray; image; feature extraction; presence call; normalization; background adjustment; expression index; comparison; software

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