A new non-enzymatic method for isolating human intervertebral disc cells preserves the phenotype of nucleus pulposus cells

[1]  K. Luk,et al.  The effects of microenvironment in mesenchymal stem cell-based regeneration of intervertebral disc. , 2013, The spine journal : official journal of the North American Spine Society.

[2]  Xinyan Tang,et al.  Changes in the Molecular Phenotype of Nucleus Pulposus Cells with Intervertebral Disc Aging , 2012, PloS one.

[3]  H. Okano,et al.  Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc , 2012, Nature Communications.

[4]  J. Lotz,et al.  Porcine intervertebral disc repair using allogeneic juvenile articular chondrocytes or mesenchymal stem cells. , 2011, Tissue engineering. Part A.

[5]  J. Bumgardner,et al.  Modeling Nucleus Pulposus Regeneration In Vitro: Mesenchymal Stem Cells, Alginate Beads, Hypoxia, Bone Morphogenetic Protein-2, and Synthetic Peptide B2A , 2011, Spine.

[6]  L. Setton,et al.  Interleukin‐17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule‐1 (ICAM‐1) expression in human intervertebral disc cells , 2011, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[7]  B. Harfe,et al.  Degeneration and regeneration of the intervertebral disc: lessons from development , 2010, Disease Models & Mechanisms.

[8]  T. Yoshikawa,et al.  Disc Regeneration Therapy Using Marrow Mesenchymal Cell Transplantation: A Report of Two Case Studies , 2010, Spine.

[9]  N. Boos,et al.  Immunohistochemical identification of notochordal markers in cells in the aging human lumbar intervertebral disc , 2010, European Spine Journal.

[10]  C. Gilchrist,et al.  Expression of Laminin Isoforms, Receptors, and Binding Proteins Unique to Nucleus Pulposus Cells of Immature Intervertebral Disc , 2009, Connective tissue research.

[11]  A. Freemont,et al.  The cellular pathobiology of the degenerate intervertebral disc and discogenic back pain. , 2008, Rheumatology.

[12]  T. Albert,et al.  Evidence for Skeletal Progenitor Cells in the Degenerate Human Intervertebral Disc , 2007, Spine.

[13]  L. Dai,et al.  The cell biology of intervertebral disc aging and degeneration , 2007, Ageing Research Reviews.

[14]  C. Gilchrist,et al.  Functional integrin subunits regulating cell–matrix interactions in the intervertebral disc , 2007, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[15]  Lori A. Setton,et al.  Molecular phenotypes of notochordal cells purified from immature nucleus pulposus , 2006, European Spine Journal.

[16]  Y. Toyama,et al.  CD24 is expressed specifically in the nucleus pulposus of intervertebral discs. , 2005, Biochemical and biophysical research communications.

[17]  Joji Mochida,et al.  Differentiation of Mesenchymal Stem Cells Transplanted to a Rabbit Degenerative Disc Model: Potential and Limitations for Stem Cell Therapy in Disc Regeneration , 2005, Spine.

[18]  Y. Kikkawa,et al.  Review: Lutheran/B-CAM: A Laminin Receptor on Red Blood Cells and in Various Tissues , 2005, Connective tissue research.

[19]  T. Albert,et al.  Differentiation of Mesenchymal Stem Cells Towards a Nucleus Pulposus-like Phenotype In Vitro: Implications for Cell-Based Transplantation Therapy , 2004, Spine.

[20]  L. Setton,et al.  Integrin expression in cells of the intervertebral disc , 2004, Journal of anatomy.

[21]  J. Ralphs,et al.  The development of fibrocartilage in the rat intervertebral disc , 1995, Anatomy and Embryology.

[22]  L. Setton,et al.  Static compression induces zonal-specific changes in gene expression for extracellular matrix and cytoskeletal proteins in intervertebral disc cells in vitro. , 2004, Matrix biology : journal of the International Society for Matrix Biology.

[23]  W. Hutton,et al.  Disc Chondrocyte Transplantation in a Canine Model: A Treatment for Degenerated or Damaged Intervertebral Disc , 2003, Spine.

[24]  K. Ando,et al.  Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potential therapeutic model for disc degeneration. , 2003, Biomaterials.

[25]  Sally Roberts,et al.  Degeneration of the intervertebral disc , 2003, Arthritis research & therapy.

[26]  H. Gruber,et al.  Autologous Intervertebral Disc Cell Implantation: A Model Using Psammomys obesus, the Sand Rat , 2002, Spine.

[27]  Michael J. Parsons,et al.  Zebrafish mutants identify an essential role for laminins in notochord formation. , 2002, Development.

[28]  L. Setton,et al.  Matrix protein gene expression in intervertebral disc cells subjected to altered osmolarity. , 2002, Biochemical and biophysical research communications.

[29]  L. Setton,et al.  Intervertebral Disc Cells Exhibit Differences in Gene Expression in Alginate and Monolayer Culture , 2001, Spine.

[30]  R. Wenger,et al.  Altered erythrocytes and a leaky block in B-cell development in CD24/HSA-deficient mice. , 1997, Blood.

[31]  M P Bevilacqua,et al.  Endothelial-leukocyte adhesion molecules. , 1993, Annual review of immunology.

[32]  B. Vernon‐roberts,et al.  A longitudinal study of the matrix changes induced in the intervertebral disc by surgical damage to the annulus fibrosus , 1992, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[33]  D. V. Van Epps,et al.  In vitro models of lymphocyte transendothelial migration. , 1992, Invasion & metastasis.

[34]  G. Andersson,et al.  Discs Degenerate Before Facets , 1990, Spine.

[35]  J. Urban,et al.  Swelling pressure of the inervertebral disc: influence of proteoglycan and collagen contents. , 1985, Biorheology.

[36]  R. Walmsley,et al.  Experimental incision of the intervertebral disc. , 1951, The Journal of bone and joint surgery. British volume.