This study offers insight into the processes of expert designers at the Jet Propulsion Laboratory (JPL) and how they make use of heuristics in the design process. A methodology for the extraction, classification, and characterization of heuristics is presented. Ten expert participants were interviewed to identify design heuristics used during early stage space mission design at JPL. In total, 101 heuristics were obtained, classified, and characterized. Through the use of postinterview surveys, participants characterized heuristics based on attributes including source/origin, applicability based on concept maturity, frequency of use, reliability, and tendency to evolve. These findings are presented, and statistically analyzed to show correlations between the participant perceptions of frequency of use, reliability, and evolution of a heuristic. Survey results and analysis aim to identify valid attributes for assessing the applicability and value of multiple heuristics for design practice in early space mission formulation.