A biocatalytic/reductive etherification approach to substituted piperidinyl ethers
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[1] T. Satoh,et al. Synthesis of Spiro[2.6]nonadienones and Spiro[3.6]decadienones by the Reaction of Cyclopropyl- and Cyclobutylmagnesium Carbenoids with Lithium Phenolates and Naphtholates , 2012 .
[2] Xiao Mei Zheng,et al. Identification of a potent, state-dependent inhibitor of Nav1.7 with oral efficacy in the formalin model of persistent pain. , 2011, Journal of medicinal chemistry.
[3] P. Milner,et al. A Practical Synthesis of DifferentiallyProtected 4,4′-Dipiperidinyl Ethers: Novel Ligandsof Pharmaceutical Interest , 2009 .
[4] Dunming Zhu,et al. Enantioselective Reduction of Diaryl Ketones Catalyzed by a Carbonyl Reductase from Sporobolomyces salmonicolor and its Mutant Enzymes , 2009 .
[5] R. Weis,et al. Antimycobacterial activity of diphenylpyraline derivatives. , 2008, European journal of medicinal chemistry.
[6] J. Shin,et al. Synthesis, in vitro assay, and molecular modeling of new piperidine derivatives having dual inhibitory potency against acetylcholinesterase and Abeta1-42 aggregation for Alzheimer's disease therapeutics. , 2007, Bioorganic & medicinal chemistry.
[7] Paul N. Devine,et al. Enzyme-catalyzed enantioselective diaryl ketone reductions. , 2007, Organic letters.
[8] T. Oriyama,et al. Iron(III) chloride-catalyzed reductive etherification of carbonyl compounds with alcohols , 2007 .
[9] I. Davies,et al. Stereoselective preparation of a cyclopentane-based NK1 receptor antagonist bearing an unsymmetrically substituted sec-sec ether. , 2006, The Journal of organic chemistry.
[10] S. Rozen,et al. A new efficient deprotection of azines, hydrazones and oximes. An excellent route for exchanging oxygen isotopes in carbonyls , 2006 .
[11] Sara R. Jones,et al. The synthesis and biological evaluation of dopamine transporter inhibiting activity of substituted diphenylmethoxypiperidines. , 2005, Bioorganic & medicinal chemistry letters.
[12] S. Chandrasekhar,et al. Reductive etherification of carbonyl compounds with alkyl trimethylsilylethers using polymethylhydrosiloxane (PMHS) and catalytic B(C6F5)3 , 2004 .
[13] J. Spencer,et al. Evidence that protons can be the active catalysts in Lewis acid mediated hetero-Michael addition reactions. , 2004, Chemistry.
[14] P. Evans,et al. Stereoselective construction of cis-2,6-disubstituted tetrahydropyrans via the reductive etherification of delta-trialkylsilyloxy substituted ketones: total synthesis of (-)-centrolobine. , 2003, Organic letters.
[15] S. Hung,et al. Cu(OTf)2-catalyzed Et3SiH-reductive etherification of various carbonyl compounds with trimethylsilyl ethers , 2003 .
[16] K. Prasad,et al. In-situ generation of Et3SiBr from BiBr3 and Et3SiH and its use in preparation of dialkyl ethers , 2002 .
[17] N. Komatsu,et al. Bismuth bromide-catalyzed reductive coupling of carbonyl compounds and its application to the synthesis of novel crownophanes , 1997 .
[18] H. Timmerman,et al. (Piperidinylalkoxy)chromones: novel antihistamines with additional antagonistic activity against leukotriene D4. , 1995, Journal of medicinal chemistry.
[19] T. Ohashi,et al. Amphoteric drugs. I. Synthesis and antiallergic activity of [4-(diphenylmethoxy)piperidino]-, [4-(diphenylmethyl)piperazinyl]- and [4-(diphenylmethylene)piperidino]alkanoic acid derivatives. , 1994, Chemical & pharmaceutical bulletin.
[20] M. Nishizawa,et al. Efficient reductive etherification of carbonyl compounds with alkoxytrimethylsilanes , 1994 .
[21] G. Olah,et al. Trimethylsilyl Iodide Catalyzed Reductive Coupling of Aldehydes with Tertiary Alkoxytrimethylsilanes to Crowded Unsymmetrical Ethers1 , 1992 .
[22] H. Nakamura,et al. Acrylamide derivatives as antiallergic agents. 2. Synthesis and structure-activity relationships of N-[4-[4-(diphenylmethyl)-1-piperazinyl]butyl]-3-(3-pyridyl)acryl amides. , 1989, Journal of medicinal chemistry.
[23] S. Campbell,et al. 2,4-Diamino-6,7-dimethoxyquinazolines. 4. 2-[4-(substituted oxyethoxy) piperidino] derivatives as alpha 1-adrenoceptor antagonists and antihypertensive agents. , 1988, Journal of medicinal chemistry.
[24] G. Olah,et al. General ether synthesis under mild acid-free conditions. Trimethylsilyl iodide catalyzed reductive coupling of carbonyl compounds with trialkylsilanes to symmetrical ethers and reductive condensation with alkoxysilanes to unsymmetrical ethers , 1987 .
[25] F. Tisserand,et al. New xanthine derivatives with potent and long lasting anti-bronchoconstrictive activity , 1987 .
[26] J. Kato,et al. A novel method for the preparation of symmetrical and unsymmetrical ethers. Trityl perchlorate promoted reduction of carbonyl compounds with triethylsilane. , 1985 .