The Anticancer Drugs

PART I: PRINCIPLES OF CANCER CHEMOTHERAPY 1. The cancer problem 2. Some milestones in the development of cancer chemotherapy 3. Determinants of drug responsiveness 4. Resistance to anticancer drugs PART II: THE ANTICANCER DRUGS 5. Antimetabolites 6. Covalent DNA binding drugs 7. Non-covalent DNA binding drugs 8. Inhibitors of chromatin function 9. Drugs affecting endocrine function PART III: CLINICAL CANCER CHEMOTHERAPY 10. Choice of drugs for cencer chemotherapy PART IV: NEW DIRECTIONS IN CANCER CHEMOTHERAPY 11. Anticancer drug development 12. Biological treatments of cancer 13. Potential targets for new anticancer drugs