High-Frequency Ultrasound (50–150 MHz) in Dermatology

In 1979 Alexander and Miller (1979) and Rukinava and Mohar (1979) reported for the first time on A-scan ultrasound of the skin using an unfocused transducer. They were able to detect echoes of the skin surface and of subsurface dermal structures. In the eighties first prototypes at 15–20 MHz have been developed and basic principles of high resolution ultrasound signal interpretation were established. This research was carried out in a few research groups around the world, in particular in England (Payne 1985), France (Querleux et al. 1988), Germany (Breitbart et al. 1983, 1986, Altmeyer 1989), Denmark (Serup 1984a, 1984b, Serup & Staberg 1987) and Japan (Murakami & Miki 1989). In the following years the knowledge on engineering concepts and dermatology applications of high frequency ultrasonic imaging has been developed significantly (Altmeyer et al. 1992).

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