Degenerative lumbar disc disease: in vivo data support the rationale for the selection of appropriate animal models.
暂无分享,去创建一个
M. Tryfonidou | M. Fusellier | C Le Visage | O Gauthier | O. Gauthier | C. Le Visage | M Fusellier | J Clouet | M Tryfonidou | C Guicheux | J. Guicheux | J. Clouet | C. Visage | C. Guicheux | Marianna A. Tryfonidou
[1] C. T. Brown,et al. FGF4 retrogene on CFA12 is responsible for chondrodystrophy and intervertebral disc disease in dogs , 2017, Proceedings of the National Academy of Sciences.
[2] Won Man Park,et al. Motion characteristics of the vertebral segments with lumbar degenerative spondylolisthesis in elderly patients , 2012, European Spine Journal.
[3] Jeffrey C. Wang,et al. The effect of needle size inducing degeneration in the rat caudal disc: evaluation using radiograph, magnetic resonance imaging, histology, and immunohistochemistry. , 2010, The spine journal : official journal of the North American Spine Society.
[4] Deli Wang,et al. Computed tomography-guided nucleus pulposus biopsy for canine intervertebral disc degeneration preparation: a radiology and histology study. , 2016, The spine journal : official journal of the North American Spine Society.
[5] I. Shapiro,et al. Role of cytokines in intervertebral disc degeneration: pain and disc content , 2014, Nature Reviews Rheumatology.
[6] Masanori Sasaki,et al. Effects of Chondroitinase ABC on Intradiscal Pressure in Sheep: An In Vivo Study , 2001, Spine.
[7] D. Purmessur,et al. Notochordal Cell-Derived Therapeutic Strategies for Discogenic Back Pain , 2013, Global spine journal.
[8] C. Montero-Menei,et al. The transpedicular surgical approach for the development of intervertebral disc targeting regenerative strategies in an ovine model , 2017, European Spine Journal.
[9] H. An,et al. Histological Features of the Degenerating Intervertebral Disc in a Goat Disc-Injury Model , 2011, Spine.
[10] J. Coates,et al. A retrospective comparison of cervical intervertebral disk disease in nonchondrodystrophic large dogs versus small dogs. , 2004, Journal of the American Animal Hospital Association.
[11] H. Wilke,et al. A New Porcine In Vivo Animal Model of Disc Degeneration: Response of Anulus Fibrosus Cells, Chondrocyte-Like Nucleus Pulposus Cells, and Notochordal Nucleus Pulposus Cells to Partial Nucleotomy , 2009, Spine.
[12] L. Bonassar,et al. Total disc replacement using a tissue-engineered intervertebral disc in vivo: new animal model and initial results , 2010, Evidence-based spine-care journal.
[13] W. Lauerman,et al. Age-related disk degeneration: preliminary report of a naturally occurring baboon model. , 1992, Journal of spinal disorders.
[14] H. Gruber,et al. Adipose-derived mesenchymal stem cells from the sand rat: transforming growth factor beta and 3D co-culture with human disc cells stimulate proteoglycan and collagen type I rich extracellular matrix , 2008, Arthritis research & therapy.
[15] Z. Lee,et al. Percutaneous image-guided delivery for the transplantation of mesenchymal stem cells in the setting of degenerated intervertebral discs. , 2012, Journal of Vascular and Interventional Radiology.
[16] P. Weinhold,et al. An in vivo model of degenerative disc disease , 2003, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[17] F. T. Wetzel,et al. Intervertebral disc degeneration adjacent to a lumbar fusion. An experimental rabbit model. , 2002, The Journal of bone and joint surgery. British volume.
[18] W. E. Stern,et al. Effects of collagenase upon the intervertebral disc in monkeys. , 1976, Journal of neurosurgery.
[19] H. Muir,et al. Vertebral osteophyte formation in experimental disc degeneration , 1980 .
[20] T. Taylor,et al. The effect of spinal fusion on intervertebral disc composition: an experimental study. , 1976, The Journal of surgical research.
[21] H. O. Sweet,et al. Progressive ankylosis, a new skeletal mutation in the mouse. , 1981, The Journal of heredity.
[22] W. Walsh,et al. A novel in vivo large animal model of lumbar spinal joint degeneration. , 2018, The spine journal : official journal of the North American Spine Society.
[23] Bernhard Meyer,et al. Minimally Invasive Transmuscular Pedicle Screw Fixation of the Thoracic and Lumbar Spine , 2006, Neurosurgery.
[24] R. Ching,et al. Intervertebral disc degeneration in a naturally occurring primate model: Radiographic and biomechanical evidence , 2008, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[25] T. Griffin,et al. Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen. , 2009, Arthritis and rheumatism.
[26] J. Ott,et al. Identification of a novel common genetic risk factor for lumbar disk disease. , 2001, JAMA.
[27] D. Elliott,et al. Young Investigator Award Winner: Validation of the Mouse and Rat Disc as Mechanical Models of the Human Lumbar Disc , 2004, Spine.
[28] H. Muir,et al. Vertebral osteophyte formation in experimental disc degeneration. Morphologic and proteoglycan changes over time. , 1980, Arthritis and rheumatism.
[29] J. W. Hirst,et al. Collagenase: An Experimental Study of Intervertebral Disc Dissolution , 1980, Spine.
[30] M. Fujii,et al. Matrix metalloproteinase (MMP)‐3 gene up‐regulation in a rat tail compression loading‐induced disc degeneration model , 2010, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[31] Koichi Masuda,et al. A Novel Rabbit Model of Mild, Reproducible Disc Degeneration by an Anulus Needle Puncture: Correlation Between the Degree of Disc Injury and Radiological and Histological Appearances of Disc Degeneration , 2005, Spine.
[32] R. Cailliet,et al. Vertebral End-Plate Changes With Aging of Human Vertebrae , 1982, Spine.
[33] V. Stanescu,et al. Nucleolysis of the Rabbit Intervertebral Disc Using Chondroitinase ABC , 1991, Spine.
[34] L. Denaro,et al. Novel stepwise model of intervertebral disc degeneration with intact annulus fibrosus to test regeneration strategies , 2018, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[35] I A Stokes,et al. Compression-induced changes in intervertebral disc properties in a rat tail model. , 1999, Spine.
[36] W. Hutton,et al. The Effect of Blocking a Nutritional Pathway to the Intervertebral Disc in the Dog Model , 2004, Journal of spinal disorders & techniques.
[37] K. Cheung,et al. How Reliable Are the Reported Genetic Associations in Disc Degeneration?: The Influence of Phenotypes, Age, Population Size, and Inclusion Sequence in 809 Patients , 2016, Spine.
[38] Joji Mochida,et al. Differentiation of Mesenchymal Stem Cells Transplanted to a Rabbit Degenerative Disc Model: Potential and Limitations for Stem Cell Therapy in Disc Regeneration , 2005, Spine.
[39] R. Taylor,et al. Balloon kyphoplasty in the management of vertebral compression fractures: an updated systematic review and meta-analysis , 2007, European Spine Journal.
[40] Mauro Alini,et al. Quantitative Magnetic Resonance Imaging of Enzymatically Induced Degradation of the Nucleus Pulposus of Intervertebral Discs , 2006, Spine.
[41] B. Harfe,et al. Needle puncture injury causes acute and long‐term mechanical deficiency in a mouse model of intervertebral disc degeneration , 2013, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[42] W. Priester. Canine intervertebral disc disease — Occurrence by age, breed, and sex among 8,117 cases , 1976 .
[43] C. Colloca,et al. Biomechancial quantification of pathologic manipulable spinal lesions: an in vivo ovine model of spondylolysis and intervertebral disc degeneration. , 2012, Journal of manipulative and physiological therapeutics.
[44] Marco Bernardini,et al. The transpedicular approach for the study of intervertebral disc regeneration strategies: in vivo characterization , 2013, European Spine Journal.
[45] R. Appleyard,et al. A Detailed Microscopic Examination of Alterations in Normal Anular Structure Induced by Mechanical Destabilization in an Ovine Model of Disc Degeneration , 2010, Spine.
[46] H. Gruber,et al. Immunolocalization of Thrombospondin in the Human and Sand Rat Intervertebral Disc , 2006, Spine.
[47] Xiang-Yang Wang,et al. Anatomy of large animal spines and its comparison to the human spine: a systematic review , 2009, European Spine Journal.
[48] Matthew G. Wiet,et al. The chondrodystrophic dog: A clinically relevant intermediate‐sized animal model for the study of intervertebral disc‐associated spinal pain , 2018, JOR spine.
[49] I. Kiviranta,et al. Proteoglycan synthesis in canine intervertebral discs after long‐distance running training , 1993, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[50] M. Ishihara,et al. An Experimental Study of the Regeneration of the Intervertebral Disc With an Allograft of Cultured Annulus Fibrosus Cells Using a Tissue-Engineering Method , 2003, Spine.
[51] Simon C Watkins,et al. Accelerated aging of intervertebral discs in a mouse model of progeria , 2010, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[52] Yejia Zhang,et al. Intervertebral Disc Degeneration in a Percutaneous Mouse Tail Injury Model , 2017, American journal of physical medicine & rehabilitation.
[53] B. Meij,et al. Increased caveolin-1 in intervertebral disc degeneration facilitates repair , 2016, Arthritis Research & Therapy.
[54] T. Hansson,et al. Experimental Disc Degeneration Due to Endplate Injury , 2004, Journal of spinal disorders & techniques.
[55] M. Asher,et al. A Comparison Between Bipedal and Quadrupedal Rats: Do Bipedal Rats Actually Assume an Upright Posture? , 2001, Spine.
[56] Jinxi Wang,et al. Genetic factors in intervertebral disc degeneration , 2016, Genes & diseases.
[57] A. Nerlich,et al. Loss of notochordal cell phenotype in 3D-cell cultures: implications for disc physiology and disc repair , 2014, Archives of Orthopaedic and Trauma Surgery.
[58] K. Yonenobu,et al. Experimental Cervical Spondylosis in the Mouse , 1991, Spine.
[59] R. Moskowitz,et al. Physicochemical properties of the aging and diabetic sand rat intervertebral disc , 1992, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[60] G. J. Verkerke,et al. Comparative anatomical dimensions of the complete human and porcine spine , 2010, European Spine Journal.
[61] Jaw-Lin Wang,et al. The Leakage Pathway and Effect of Needle Gauge on Degree of Disc Injury Post Anular Puncture: A Comparative Study Using Aged Human and Adolescent Porcine Discs , 2007, Spine.
[62] M. Fusellier,et al. Longitudinal Comparison of Enzyme- and Laser-Treated Intervertebral Disc by MRI, X-Ray, and Histological Analyses Reveals Discrepancies in the Progression of Disc Degeneration: A Rabbit Study , 2016, BioMed research international.
[63] Thijs Grünhagen,et al. Notochordal intervertebral disc cells: sensitivity to nutrient deprivation. , 2009, Arthritis and rheumatism.
[64] M. Cohn,et al. Identification of nucleus pulposus precursor cells and notochordal remnants in the mouse: Implications for disk degeneration and chordoma formation , 2008, Developmental dynamics : an official publication of the American Association of Anatomists.
[65] M. Kurosaka,et al. A rat tail temporary static compression model reproduces different stages of intervertebral disc degeneration with decreased notochordal cell phenotype , 2014, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[66] J. Adler,et al. Early Onset of Disk Degeneration and Spondylosis in Sand Rats (Psammomys Obesus) , 1983, Veterinary pathology.
[67] H. Helminen,et al. Proteoglycans in the intervertebral disc of young dogs following strenuous running exercise. , 1994, Connective tissue research.
[68] C. Zeiss,et al. Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia. , 2014, Bone.
[69] Ian A. F. Stokes,et al. Mechanical Conditions That Accelerate Intervertebral Disc Degeneration: Overload Versus Immobilization , 2004, Spine.
[70] Mauro Alini,et al. A Nucleotomy Model with Intact Annulus Fibrosus to Test Intervertebral Disc Regeneration Strategies. , 2015, Tissue engineering. Part C, Methods.
[71] A. Nerlich,et al. New In Vivo Animal Model to Create Intervertebral Disc Degeneration and to Investigate the Effects of Therapeutic Strategies to Stimulate Disc Regeneration , 2002, Spine.
[72] Hendrik Schmidt,et al. Is the ovine intervertebral disc a small human one? A finite element model study. , 2013, Journal of the mechanical behavior of biomedical materials.
[73] G. Buttermann,et al. Mature runt cow lumbar intradiscal pressures and motion segment biomechanics. , 2009, The spine journal : official journal of the North American Spine Society.
[74] Brent L. Showalter,et al. Comparison of Animal Discs Used in Disc Research to Human Lumbar Disc: Torsion Mechanics and Collagen Content , 2012, Spine.
[75] Zachary R. Schoepflin,et al. Disc in flames: Roles of TNF-α and IL-1β in intervertebral disc degeneration. , 2015, European cells & materials.
[76] F. Galbusera,et al. Finite element comparison between the human and the ovine lumbar intervertebral disc. , 2017, Muscles, ligaments and tendons journal.
[77] G. Banfi,et al. Pathophysiology of the human intervertebral disc. , 2008, The international journal of biochemistry & cell biology.
[78] H. Muir,et al. Experimental intervertebral disc degeneration: morphologic and proteoglycan changes over time. , 1981, Arthritis and rheumatism.
[79] A. Jackson,et al. Relationship between solute transport properties and tissue morphology in human annulus fibrosus , 2009, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[80] J. Lotz,et al. The effect of static in vivo bending on the murine intervertebral disc. , 2001, The spine journal : official journal of the North American Spine Society.
[81] W. Brehm,et al. Morphometrical dimensions of the sheep thoracolumbar vertebrae as seen on digitised CT images , 2013, Laboratory animal research.
[82] K. Ando,et al. Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potential therapeutic model for disc degeneration. , 2003, Biomaterials.
[83] Dawn M Elliott,et al. Comparison of Animal Discs Used in Disc Research to Human Lumbar Disc: Axial Compression Mechanics and Glycosaminoglycan Content , 2008, Spine.
[84] S. Richardson,et al. An understanding of intervertebral disc development, maturation and cell phenotype provides clues to direct cell-based tissue regeneration therapies for disc degeneration , 2014, European Spine Journal.
[85] H. An,et al. Animal models for human disc degeneration. , 2005, The spine journal : official journal of the North American Spine Society.
[86] Xiaojuan Li,et al. In Vivo Intervertebral Disc Characterization Using Magnetic Resonance Spectroscopy and T1&rgr; Imaging: Association With Discography and Oswestry Disability Index and Short Form-36 Health Survey , 2012, Spine.
[87] T. Smit,et al. Experimental Intervertebral Disc Degeneration Induced by Chondroitinase ABC in the Goat , 2007, Spine.
[88] Hai-xing Sun,et al. Intervertebral disk degeneration: T1ρ MR imaging of human and animal models. , 2013, Radiology.
[89] D. Sakai,et al. Human nucleus pulposus cells significantly enhanced biological properties in a coculture system with direct cell‐to‐cell contact with autologous mesenchymal stem cells , 2010, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[90] D. Chan,et al. Coming together is a beginning: the making of an intervertebral disc. , 2014, Birth defects research. Part C, Embryo today : reviews.
[91] Samuel K. Cho,et al. Assessment of functional and behavioral changes sensitive to painful disc degeneration , 2015, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[92] H. Wilke,et al. In vitro and in silico investigations of disc nucleus replacement , 2012, Journal of The Royal Society Interface.
[93] G R Fernie,et al. An anatomical comparison of the human and bovine thoracolumbar spine , 1986, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[94] Jianzhong Hu,et al. 3D characterization of morphological changes in the intervertebral disc and endplate during aging: A propagation phase contrast synchrotron micro-tomography study , 2017, Scientific Reports.
[95] Daniel H K Chow,et al. The effect of cyclic compression on the mechanical properties of the inter-vertebral disc: an in vivo study in a rat tail model. , 2003, Clinical biomechanics.
[96] M. Nogueira-Barbosa,et al. Experimental model of intervertebral disc degeneration by needle puncture in Wistar rats , 2013, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
[97] H. Wilke,et al. Preliminary Investigations on Intradiscal Pressures during Daily Activities: An In Vivo Study Using the Merino Sheep , 2013, PloS one.
[98] E. Thonar,et al. Osteogenic protein-1 is most effective in stimulating nucleus pulposus and annulus fibrosus cells to repair their matrix after chondroitinase ABC-induced in vitro chemonucleolysis. , 2005, The spine journal : official journal of the North American Spine Society.
[99] Ying-ming Chen,et al. Computed tomography-guided sub-end plate injection of pingyangmycin for a novel rabbit model of slowly progressive disc degeneration. , 2015, The spine journal : official journal of the North American Spine Society.
[100] E. H. Margulies,et al. An Expressed Fgf4 Retrogene Is Associated with Breed-Defining Chondrodysplasia in Domestic Dogs , 2009, Science.
[101] R. Hammer,et al. Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human β 2m: An animal model of HLA-B27-associated human disorders , 1990, Cell.
[102] N. Theodore,et al. Biomechanical and Endplate Effects on Nutrient Transport in the Intervertebral Disc. , 2017, World neurosurgery.
[103] Jeffrey C Lotz,et al. Animal Models of Intervertebral Disc Degeneration: Lessons Learned , 2004, Spine.
[104] D. Jin,et al. Establishing a disc degeneration model using computed tomography-guided percutaneous puncture technique in the rabbit. , 2013, The Journal of surgical research.
[105] B. Harfe,et al. Degeneration and regeneration of the intervertebral disc: lessons from development , 2010, Disease Models & Mechanisms.
[106] K. Kaneda,et al. Effects of Chondroitinase ABC and Chymopapain on Spinal Motion Segment Biomechanics: An In Vivo Biomechanical, Radiologic, and Histologic Canine Study , 1997, Spine.
[107] T. Oegema,et al. Residual chymopapain activity after chemonucleolysis in normal intervertebral discs in dogs. , 1992, The Journal of bone and joint surgery. American volume.
[108] Huilin Yang,et al. The expression of Fas ligand on normal and stabbed-disc cells in a rabbit model of intervertebral disc degeneration: a possible pathogenesis. , 2007, Journal of neurosurgery. Spine.
[109] K. Mimatsu,et al. Experimental Chemonucleolysis With Chondroitinase ABC in Monkeys , 1996, Spine.
[110] R. Mason,et al. Changes in mouse intervertebral-disc proteoglycan synthesis with age. Hereditary kyphoscoliosis is associated with elevated synthesis. , 1986, The Biochemical journal.
[111] T. Smit,et al. Reproducible Long-term Disc Degeneration in a Large Animal Model , 2008, Spine.
[112] V. Pedrini,et al. Age-related variations in proteinpolysaccharides from human nucleus pulposus, annulus fibrosus, and costal cartilage. , 1969, The Journal of bone and joint surgery. American volume.
[113] A. Kobrine,et al. Effects of collagenase and chymopapain on spinal nerves and intervertebral discs of cynomolgus monkeys. , 1986, Journal of neurosurgery.
[114] J. Melrose,et al. Intervertebral Disc Reconstitution After Chemonucleolysis With Chymopapain is Dependent on Dosage: An Experimental Study in Beagle Dogs , 1996, Spine.
[115] N. Pleshko,et al. A novel mouse model of intervertebral disc degeneration shows altered cell fate and matrix homeostasis. , 2018, Matrix biology : journal of the International Society for Matrix Biology.
[116] A. Lai,et al. Looking beyond the intervertebral disc: the need for behavioral assays in models of discogenic pain , 2017, Annals of the New York Academy of Sciences.
[117] K. Bartels,et al. Use of the holmium yttrium aluminum garnet laser for percutaneous thoracolumbar intervertebral disk ablation in dogs. , 1996, Journal of the American Veterinary Medical Association.
[118] Lawrence J Bonassar,et al. Image‐based tissue engineering of a total intervertebral disc implant for restoration of function to the rat lumbar spine , 2012, NMR in biomedicine.
[119] R. Mason,et al. Intervertebral disc degeneration in adult mice with hereditary kyphoscoliosis , 1984, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[120] B. Brisson. Intervertebral disc disease in dogs. , 2010, The Veterinary clinics of North America. Small animal practice.
[121] Samuel K. Cho,et al. Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development , 2013, Arthritis Research & Therapy.
[122] A. Sudo,et al. Effect of diminished flow in rabbit lumbar arteries on intervertebral disc matrix changes using MRI T2-mapping and histology , 2019, BMC Musculoskeletal Disorders.
[123] B. Caterson,et al. Matrix Metalloproteinases And Aggrecanase: Their Role in Disorders of the Human Intervertebral Disc , 2000, Spine.
[124] L. Claes,et al. Anatomy of the sheep spine and its comparison to the human spine , 1997, The Anatomical record.
[125] B. Vernon‐roberts,et al. 1990 Volvo Award in experimental studies. Anulus tears and intervertebral disc degeneration. An experimental study using an animal model. , 1990 .
[126] J. Lotz,et al. Porcine intervertebral disc repair using allogeneic juvenile articular chondrocytes or mesenchymal stem cells. , 2011, Tissue engineering. Part A.
[127] L. Ala‐Kokko,et al. Intervertebral disc degeneration in relation to the COL9A3 and the IL-1ß gene polymorphisms , 2006, European Spine Journal.
[128] T. Ochi,et al. Progressive degeneration of articular cartilage and intervertebral discs , 1996, International Orthopaedics.
[129] A B Schultz,et al. The Effects of Chemonucleolysis on the Mechanical Properties of the Canine Lumbar Disc , 1985, Spine.
[130] Y. Maugars,et al. Characterization of the age-dependent intervertebral disc changes in rabbit by correlation between MRI, histology and gene expression , 2011, BMC Musculoskeletal Disorders.
[131] B. Meij,et al. The Myth of Fibroid Degeneration in the Canine Intervertebral Disc: A Histopathological Comparison of Intervertebral Disc Degeneration in Chondrodystrophic and Nonchondrodystrophic Dogs , 2014, Veterinary pathology.
[132] S. Hochman,et al. Disc degeneration induces a mechano-sensitization of disc afferent nerve fibers that associates with low back pain. , 2019, Osteoarthritis and cartilage.
[133] B. Kaphalia,et al. Torsional injury resulting in disc degeneration: I. An in vivo rabbit model. , 1998, Journal of spinal disorders.
[134] H. Deramond,et al. [Preliminary note on the treatment of vertebral angioma by percutaneous acrylic vertebroplasty]. , 1987, Neuro-Chirurgie.
[135] Z. Shao,et al. Mechanisms of endogenous repair failure during intervertebral disc degeneration. , 2019, Osteoarthritis and cartilage.
[136] R. Moskowitz,et al. Effect of age on pyridinoline and pentosidine matrix cross-links in the desert sand rat intervertebral disc , 1994 .
[137] Su-jin Kim,et al. Quantitative Analysis of Disc Degeneration Using Axial T2 Mapping in a Percutaneous Annular Puncture Model in Rabbits , 2016, Korean journal of radiology.
[138] R. Hammer,et al. Susceptibility to inflammatory disease in HLA-B27 transgenic rat lines correlates with the level of B27 expression. , 1993, Journal of immunology.
[139] R. Pfuhl,et al. Percutaneous Disc Decompression with Nucleoplasty–Volumetry of the Nucleus Pulposus Using Ultrahigh-Field MRI , 2012, PloS one.
[140] Walter F. Stewart,et al. Back Pain Exacerbations and Lost Productive Time Costs in United States Workers , 2006, Spine.
[141] David Hwang,et al. Degenerative Anular Changes Induced by Puncture Are Associated With Insufficiency of Disc Biomechanical Function , 2009, Spine.
[142] A S Carter,et al. CD44 expression in the developing and growing rat intervertebral disc , 2000, Developmental dynamics : an official publication of the American Association of Anatomists.
[143] J. Lotz,et al. Effects of Controlled Dynamic Disc Distraction on Degenerated Intervertebral Discs: An in Vivo Study on the Rabbit Lumbar Spine Model , 2005, Spine.
[144] B. Meij,et al. Potential regenerative treatment strategies for intervertebral disc degeneration in dogs , 2014, BMC Veterinary Research.
[145] W. Brehm,et al. Is sheep lumbar spine a suitable alternative model for human spinal researches? Morphometrical comparison study , 2013, Laboratory animal research.
[146] A. Hashimoto,et al. Experimental chemonucleolysis with chymopapain in canine intervertebral disks. , 1993, The Journal of veterinary medical science.
[147] Farfan Hf,et al. Pathologic changes with intervertebral joint rotational instability in the rabbit. , 1971 .
[148] J. Iatridis,et al. A role for TNFα in intervertebral disc degeneration: a non-recoverable catabolic shift. , 2013, Biochemical and biophysical research communications.
[149] K. Miyahara,et al. Investigation of the short-term effect of chemonucleolysis with chondroitinase ABC. , 2001, The Journal of veterinary medical science.
[150] J. Le Bideau,et al. Innovative strategies for intervertebral disc regenerative medicine: From cell therapies to multiscale delivery systems. , 2017, Biotechnology advances.
[151] Benjamin Gantenbein-Ritter,et al. Papain-induced in vitro disc degeneration model for the study of injectable nucleus pulposus therapy. , 2013, The spine journal : official journal of the North American Spine Society.
[152] F. Vittur,et al. Degenerative Changes of Porcine Intervertebral Disc Induced by Vertebral Endplate Injuries , 2005, Spine.
[153] B. Meij,et al. Biologic canine and human intervertebral disc repair by notochordal cell-derived matrix: from bench towards bedside , 2018, Oncotarget.
[154] P. Bierling,et al. A novel in vivo porcine model of intervertebral disc degeneration induced by cryoinjury , 2018, International Orthopaedics.
[155] A. Camus,et al. Intervertebral disc regeneration: a great challenge for tissue engineers. , 2014, Trends in biotechnology.
[156] K. Mohammad,et al. Dystrophic Spinal Deformities in a Neurofibromatosis Type 1 Murine Model , 2015, PloS one.
[157] D. Gregory,et al. A comparison between porcine, ovine, and bovine intervertebral disc anatomy and single lamella annulus fibrosus tensile properties , 2016, Journal of morphology.
[158] A. Milby,et al. A large animal model that recapitulates the spectrum of human intervertebral disc degeneration. , 2017, Osteoarthritis and cartilage.
[159] W. Welch,et al. Relevant Anatomic and Morphological Measurements of the Rat Spine: Considerations for Rodent Models of Human Spine Trauma , 2015, Spine.
[160] N. Iwasaki,et al. In Vivo Mouse Intervertebral Disc Degeneration Model Based on a New Histological Classification , 2016, PloS one.
[161] Nicholas Theodore,et al. Genetics of the degenerated intervertebral disc. , 2012, World neurosurgery.
[162] A. Lai,et al. Reliability of radiographic intervertebral disc height measurement for in vivo rat-tail model. , 2007, Medical engineering & physics.
[163] C. L. Le Maitre,et al. Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes. , 2015, Osteoarthritis and cartilage.
[164] J. Urban,et al. Nutrition of the Intervertebral Disc , 2004, Spine.
[165] J. Ralphs,et al. Are animal models useful for studying human disc disorders/degeneration? , 2007, European Spine Journal.
[166] E. Chao,et al. Biomechanical Analysis of Canine Intervertebral Discs After Chymopapain Injection: A Preliminary Report , 1983, Spine.
[167] Yoshihiko Yamada,et al. Chondrodysplasia of gene knockout mice for aggrecan and link protein , 2002, Glycoconjugate Journal.
[168] J. Kimura,et al. Pathological mechanism of idiopathic scoliosis: experimental scoliosis in pinealectomized rats , 2005, European Spine Journal.
[169] K. Kaneda,et al. Changes in the nucleus pulposus of the intervertebral disc in bipedal mice. A light and electron microscopic study. , 1983, Clinical orthopaedics and related research.
[170] I. Kiviranta,et al. Effect of Running Exercise on Proteoglycans and Collagen Content in the Intervertebral Disc of Young Dogs , 1993, International Journal of Sports Medicine.
[171] M. Hyttinen,et al. Premature Vertebral Endplate Ossification and Mild Disc Degeneration in Mice After Inactivation of One Allele Belonging to the Col2a1 Gene for Type II Collagen , 2001, Spine.
[172] E. Wu,et al. Age-related degeneration of lumbar intervertebral discs in rabbits revealed by deuterium oxide-assisted MRI. , 2008, Osteoarthritis and cartilage.
[173] R. Silberberg. The vertebral column of diabetic sand rats (Psammomys obesus). , 1988, Experimental cell biology.
[174] Pascal Swider,et al. Influence of Location, Fluid Flow Direction, and Tissue Maturity on the Macroscopic Permeability of Vertebral End Plates , 2008, Spine.
[175] M. Pfeiffer,et al. Degeneration model of the porcine lumbar motion segment: effects of various intradiscal procedures , 2006, European Spine Journal.
[176] Christopher J Hunter,et al. Cytomorphology of notochordal and chondrocytic cells from the nucleus pulposus: a species comparison , 2004, Journal of anatomy.
[177] Harvey E. Smith,et al. Correlations between quantitative T2 and T1ρ MRI, mechanical properties and biochemical composition in a rabbit lumbar intervertebral disc degeneration model , 2016, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[178] J. Vandeweerd,et al. Prevalence of Age-Related Changes in Ovine Lumbar Intervertebral Discs during Computed Tomography and Magnetic Resonance Imaging. , 2016, Comparative medicine.
[179] V. Haughton,et al. Effect of disk maturation on diffusion of low-molecular-weight gadolinium complexes: an experimental study in rabbits. , 1995, AJNR. American journal of neuroradiology.
[180] Huilin Yang,et al. Effect of Static Compression Loads on Intervertebral Disc: An in Vivo Bent Rat Tail Model , 2018, Orthopaedic surgery.
[181] Ann L. Johnson,et al. Radiographic and Histologic Effects of Chondroitinase ABC on Normal Canine Lumbar Intervertebral Disc , 1991, Spine.
[182] D. Hukins,et al. Sheep lumbar intervertebral discs as models for human discs. , 2002, Clinical biomechanics.
[183] Hai-xing Sun,et al. In vivo experimental intervertebral disc degeneration induced by bleomycin in the rhesus monkey , 2014, BMC Musculoskeletal Disorders.
[184] J. Nyman,et al. Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I. , 2011, Human molecular genetics.
[185] M. Pinhal,et al. STUDIES OF MOLECULAR CHANGES IN INTERVERTEBRAL DISC DEGENERATION IN ANIMAL MODEL , 2016, Acta ortopedica brasileira.
[186] R. Moskowitz,et al. Spondylosis in sand rats: A model of intervertebral disc degeneration and hyperostosis , 1990, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[187] Vincenzo Denaro,et al. Biomechanical Evaluation of Transpedicular Nucleotomy With Intact Annulus Fibrosus , 2017, Spine.
[188] B. Stoffel‐Wagner,et al. Genetic Factors. , 2016, Deutsches Arzteblatt international.
[189] T. Taylor,et al. The effect of spinal fusion on the collagen and proteoglycans of the canine intervertebral disc. , 1978, The Journal of surgical research.
[190] H. Holzhausen,et al. Intervertebral Disc Regeneration , 2022 .
[191] C. J. McGrath,et al. Effect of exchange rate return on volatility spill-over across trading regions , 2012 .
[192] T. Takala,et al. Collagens in the injured porcine intervertebral disc , 1994, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[193] L. Setton,et al. Early-onset degeneration of the intervertebral disc and vertebral end plate in mice deficient in type IX collagen. , 2008, Arthritis and rheumatism.
[194] T. Oegema,et al. Chymopapain, chemonucleolysis, and nucleus pulposus regeneration. , 1983, The Journal of bone and joint surgery. American volume.
[195] M. Fehlings,et al. Notochordal cells protect nucleus pulposus cells from degradation and apoptosis: implications for the mechanisms of intervertebral disc degeneration , 2011, Arthritis research & therapy.
[196] S. Eisenstein,et al. Biochemical changes in intervertebral disc degeneration. , 1981, Biochimica et biophysica acta.
[197] T. Oegema,et al. Notochordal cells interact with nucleus pulposus cells: regulation of proteoglycan synthesis. , 1999, Experimental cell research.
[198] F. Kandziora,et al. [Partial nucleotomy of the ovine disc as an in vivo model for disc degeneration]. , 2009, Zeitschrift fur Orthopadie und Unfallchirurgie.
[199] H. Farfan,et al. Pathologic changes with intervertebral joint rotational instability in the rabbit. , 1971, Canadian journal of surgery. Journal canadien de chirurgie.
[200] M. Schendel,et al. Magnetic Resonance Imaging and Biological Changes in Injured Intervertebral Discs Under Normal and Increased Mechanical Demands , 1996, Spine.
[201] C. Mazel,et al. The Intervertebral Disc: Physiology and Pathology of a Brittle Joint. , 2018, World neurosurgery.
[202] G. Voorhout,et al. Evaluation of intervertebral disk degeneration in chondrodystrophic and nonchondrodystrophic dogs by use of Pfirrmann grading of images obtained with low-field magnetic resonance imaging. , 2011, American journal of veterinary research.
[203] H. Okano,et al. Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc , 2012, Nature Communications.
[204] J H van Dieën,et al. Mechanics and biology in intervertebral disc degeneration: a vicious circle. , 2015, Osteoarthritis and cartilage.
[205] Bin Han,et al. A Simple Disc Degeneration Model Induced by Percutaneous Needle Puncture in the Rat Tail , 2008, Spine.
[206] James C. Iatridis,et al. Needle puncture injury of the rat intervertebral disc affects torsional and compressive biomechanics differently , 2010, European Spine Journal.
[207] J. Griffin,et al. Canine thoracolumbar invertebral disk disease: diagnosis, prognosis, and treatment. , 2009, Compendium.
[208] F. Berger,et al. MRI T2* mapping correlates with biochemistry and histology in intervertebral disc degeneration in a large animal model , 2015, European Spine Journal.
[209] Steve D. M. Brown,et al. Molecular phenotyping of the mouse ky mutant reveals UCP1 upregulation at the neuromuscular junctions of dystrophic soleus muscle , 2004, Neuromuscular Disorders.
[210] J. Urban,et al. Bovine explant model of degeneration of the intervertebral disc , 2008, BMC musculoskeletal disorders.
[211] F. Williams,et al. Intervertebral Disc Biology: Genetic Basis of Disc Degeneration , 2018, Current Molecular Biology Reports.
[212] G. Grimandi,et al. Laser-treated Nucleus pulposus as an innovative model of intervertebral disc degeneration , 2012, Experimental biology and medicine.
[213] Mauro Alini,et al. The Transpedicular Approach As an Alternative Route for Intervertebral Disc Regeneration , 2013, Spine.
[214] Wei Li,et al. Quantitative T2 relaxation time and magnetic transfer ratio predict endplate biochemical content of intervertebral disc degeneration in a canine model , 2015, BMC Musculoskeletal Disorders.
[215] Song Ho Chang,et al. A Mouse Intervertebral Disc Degeneration Model by Surgically Induced Instability , 2017, Spine.
[216] D. Sakai,et al. Effect of cell number on mesenchymal stem cell transplantation in a canine disc degeneration model , 2010, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[217] B. Brisson,et al. Comparison between computed tomography, fluoroscopy, and ultrasonography for guiding percutaneous injection of the canine intervertebral disc. , 2014, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.
[218] H. Kurihara,et al. Chemonucleolytic Effects of Chondroitinase ABC on Normal Rabbit Intervertebral Discs: Course of Action up to 10 Days Postinjection and Minimum Effective Dose , 1996, Spine.
[219] Daniel H K Chow,et al. Changes in nuclear composition following cyclic compression of the intervertebral disc in an in vivo rat-tail model. , 2004, Medical engineering & physics.
[220] Jeffrey C Lotz,et al. Biological response of the intervertebral disc to dynamic loading. , 2004, Journal of biomechanics.
[221] Gustav J Strijkers,et al. Quantitative MRI in early intervertebral disc degeneration: T1rho correlates better than T2 and ADC with biomechanics, histology and matrix content , 2018, PloS one.
[222] Sounok Sen,et al. An In Vivo Model of Reduced Nucleus Pulposus Glycosaminoglycan Content in the Rat Lumbar Intervertebral Disc , 2008, Spine.
[223] J. Mansour,et al. Biomechanical, Radiologic, and Histopathologic Correlations in the Pathogenesis of Experimental Intervertebral Disc Disease , 1994, Spine.
[224] H. Chun,et al. Percutaneous Needle Puncture Technique to Create a Rabbit Model with Traumatic Degenerative Disk Disease. , 2015, World neurosurgery.
[225] J. Guevar,et al. The effect of kyphoscoliosis on intervertebral disc degeneration in dogs. , 2014, Veterinary journal.
[226] W. Hutton,et al. Disc Degeneration in the Rabbit: A Biochemical and Radiological Comparison Between Four Disc Injury Models , 2005, Spine.
[227] Dawn M. Elliott,et al. Comparison of Animals Used in Disc Research to Human Lumbar Disc Geometry , 2007, Spine.
[228] Lars G Gilbertson,et al. A Slowly Progressive and Reproducible Animal Model of Intervertebral Disc Degeneration Characterized by MRI, X-Ray, and Histology , 2005, Spine.
[229] P. Roughley,et al. Analysis of aggrecan catabolism by immunoblotting and immunohistochemistry. , 2012, Methods in molecular biology.
[230] G. Beaudoin,et al. Evaluation of quantitative magnetic resonance imaging, biochemical and mechanical properties of trypsin‐treated intervertebral discs under physiological compression loading , 2008, Journal of magnetic resonance imaging : JMRI.
[231] H. Gruber,et al. Autologous Intervertebral Disc Cell Implantation: A Model Using Psammomys obesus, the Sand Rat , 2002, Spine.
[232] J. Coyne,et al. A novel approach to the use of animals in studies of pain: validation of the canine brief pain inventory in canine bone cancer. , 2009, Pain medicine.
[233] M. Aebi,et al. The human lumbar intervertebral disc: evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration. , 1996, The Journal of clinical investigation.
[234] S. Ferguson,et al. Organ culture bioreactors--platforms to study human intervertebral disc degeneration and regenerative therapy. , 2015, Current stem cell research & therapy.
[235] L. Lescaudron,et al. The lumbar intervertebral disc: from embryonic development to degeneration. , 2014, Joint, bone, spine : revue du rhumatisme.
[236] J. Lotz,et al. Stab Incision for Inducing Intervertebral Disc Degeneration in the Rat , 2007, Spine.
[237] K. Lindblom. Intervertebral-disc degeneration considered as a pressure atrophy. , 1957, The Journal of bone and joint surgery. American volume.
[238] K. Hasty,et al. Aging affects response to cyclic tensile stretch: paradigm for intervertebral disc degeneration. , 2011, European cells & materials.
[239] B. Vernon‐roberts,et al. Intervertebral disc degeneration , 1993, European Spine Journal.
[240] L Claes,et al. ISSLS Prize Winner: A Novel Approach to Determine Trunk Muscle Forces During Flexion and Extension: A Comparison of Data From an In Vitro Experiment and In Vivo Measurements , 2003, Spine.
[241] L. Benneker,et al. Development of an in vivo experimental model for percutaneous vertebroplasty in sheep , 2012, Veterinary and Comparative Orthopaedics and Traumatology.
[242] E. Thonar,et al. The Dose‐Related Effect of Intradiscal Chymopapain on Rabbit Intervertebral Discs , 1994, Spine.
[243] G. Balian,et al. Collagen and Proteoglycan Abnormalities in the GDF-5-Deficient Mice and Molecular Changes When Treating Disk Cells With Recombinant Growth Factor , 2004, Spine.
[244] N. Iwasaki,et al. Age‐related spontaneous lumbar intervertebral disc degeneration in a mouse model , 2017, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[245] M. Adams,et al. What is Intervertebral Disc Degeneration, and What Causes It? , 2006, Spine.
[246] Anne-Sofie Lagerstedt,et al. The Dog as an Animal Model for Intervertebral Disc Degeneration? , 2012, Spine.
[247] Sangbong Ko,et al. Comparison of the Extent of Degeneration among the Normal Disc, Immobilized Disc, and Immobilized Disc with an Endplate Fracture , 2017, Clinics in orthopedic surgery.
[248] J. G. Bledsoe,et al. Developing a Mechanical and Chemical Model of Degeneration in Young Bovine Lumbar Intervertebral Disks and Reversing Loss in Mechanical Function , 2014, Journal of spinal disorders & techniques.
[249] J. Guevar,et al. A proposed radiographic classification scheme for congenital thoracic vertebral malformations in brachycephalic "screw-tailed" dog breeds. , 2014, Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association.
[250] C. Byron,et al. Bone architecture and disc degeneration in the lumbar spine of mice lacking GDF‐8 (myostatin) , 2003, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[251] W. Ehler,et al. Spontaneous disc degeneration in the baboon model: magnetic resonance imaging and histopathologic correlation. , 2001, Journal of medical primatology.
[252] Edward L. Compere,et al. THE NORMAL AND PATHOLOGICAL PHYSIOLOGY OF THE NUCLEUS PULPOSUS OF THE INTERVERTEBRAL DISC , 1932 .
[253] J. Cassidy,et al. A Study of the Effects of Bipedism and Upright Posture on the Lumbosacral Spine and Paravertebral Muscles of the Wistar Rat , 1988, Spine.
[254] J. Melrose,et al. Increased Nerve and Blood Vessel Ingrowth Associated With Proteoglycan Depletion in an Ovine Anular Lesion Model of Experimental Disc Degeneration , 2002, Spine.
[255] N. Suwankong,et al. Assessment of decompressive surgery in dogs with degenerative lumbosacral stenosis using force plate analysis and questionnaires. , 2007, Veterinary surgery : VS.
[256] G. Jenkin,et al. A Review of Animal Models of Intervertebral Disc Degeneration: Pathophysiology, Regeneration, and Translation to the Clinic , 2016, BioMed research international.
[257] W. Hutton,et al. Intervertebral Disc Repair Using Adipose Tissue-Derived Stem and Regenerative Cells: Experiments in a Canine Model , 2009, Spine.