Copy number variation of scavenger-receptor cysteine-rich domains within DMBT1 and Crohn's disease

[1]  Fengtang Yang,et al.  Evolution of the rapidly mutating human salivary agglutinin gene (DMBT1) and population subsistence strategy , 2015, Proceedings of the National Academy of Sciences.

[2]  Carl A. Anderson,et al.  Genetic studies of Crohn's disease: Past, present and future , 2014, Best practice & research. Clinical gastroenterology.

[3]  Johanna C Andersson-Assarsson,et al.  Low copy number of the salivary amylase gene predisposes to obesity , 2014, Nature Genetics.

[4]  A. Franke,et al.  Intestinal DMBT1 Expression Is Modulated by Crohn’s Disease-Associated IL23R Variants and by a DMBT1 Variant Which Influences Binding of the Transcription Factors CREB1 and ATF-2 , 2013, PloS one.

[5]  P. Sham,et al.  Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases , 2011, Genetic epidemiology.

[6]  B. Vainer,et al.  Alpha-Defensin DEFA1A3 Gene Copy Number Elevation in Danish Crohn’s Disease Patients , 2011, Digestive Diseases and Sciences.

[7]  P. Andersen,et al.  Determination of Beta-Defensin Genomic Copy Number in Different Populations: A Comparison of Three Methods , 2011, PloS one.

[8]  Christopher G Mathew,et al.  Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease. , 2010, Human molecular genetics.

[9]  Tariq Ahmad,et al.  Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci , 2010, Nature Genetics.

[10]  U. Holmskov,et al.  Review: Gp-340/DMBT1 in mucosal innate immunity , 2010, Innate immunity.

[11]  Jake K. Byrnes,et al.  Genome-wide association study of copy number variation in 16,000 cases of eight common diseases and 3,000 shared controls , 2010, Nature.

[12]  R. W. Bentley,et al.  Association of Higher DEFB4 Genomic Copy Number With Crohn's Disease , 2010, The American Journal of Gastroenterology.

[13]  Louise V Wain,et al.  Genomic copy number variation, human health, and disease , 2009, The Lancet.

[14]  Ashu Sharma,et al.  Leucine-rich Repeats of Bacterial Surface Proteins Serve as Common Pattern Recognition Motifs of Human Scavenger Receptor gp340* , 2009, The Journal of Biological Chemistry.

[15]  Tomas W. Fitzgerald,et al.  A robust statistical method for case-control association testing with copy number variation , 2008, Nature Genetics.

[16]  S. Larsen,et al.  Genetic and environmental factors as predictors of disease severity and extent at time of diagnosis in an inception cohort of inflammatory bowel disease, Copenhagen County and City 2003-2005. , 2008, Journal of Crohn's & colitis.

[17]  B. Roe,et al.  Effects of Muclin (Dmbt1) deficiency on the gastrointestinal system. , 2008, American journal of physiology. Gastrointestinal and liver physiology.

[18]  A. Poustka,et al.  DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease. , 2007, Gastroenterology.

[19]  A. Poustka,et al.  Regulation of DMBT1 via NOD2 and TLR4 in Intestinal Epithelial Cells Modulates Bacterial Recognition and Invasion1 , 2007, The Journal of Immunology.

[20]  S. Fisher,et al.  A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5. , 2007, Gastroenterology.

[21]  M. den Heijer,et al.  Accurate, high-throughput typing of copy number variation using paralogue ratios from dispersed repeats , 2006, Nucleic acids research.

[22]  Bernhard Radlwimmer,et al.  A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon. , 2006, American journal of human genetics.

[23]  A. Poustka,et al.  Bacteria Binding by DMBT1/SAG/gp-340 Is Confined to the VEVLXXXXW Motif in Its Scavenger Receptor Cysteine-rich Domains* , 2004, Journal of Biological Chemistry.

[24]  R. Baker,et al.  Prevalence and management of inflammatory bowel disease: a cross-sectional study from central England , 2003, European journal of gastroenterology & hepatology.

[25]  A. Poustka,et al.  CRP‐ductin, the mouse homologue of gp‐340/deleted in malignant brain tumors 1 (DMBT1), binds gram‐positive and gram‐negative bacteria and interacts with lung surfactant protein D , 2003, European journal of immunology.

[26]  Jan G. M. Bolscher,et al.  Identification of the Bacteria-binding Peptide Domain on Salivary Agglutinin (gp-340/DMBT1), a Member of the Scavenger Receptor Cysteine-rich Superfamily* , 2002, The Journal of Biological Chemistry.

[27]  D. Louis,et al.  DMBT1 polymorphisms: relationship to malignant glioma tumorigenesis. , 2002, Cancer research.

[28]  Jan Mollenhauer,et al.  DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3–26.1 is deleted in malignant brain tumours , 1997, Nature Genetics.

[29]  David C. Wilson,et al.  Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease , 2012, Nature.

[30]  André Reis,et al.  Psoriasis is associated with increased beta-defensin genomic copy number. , 2008, Nature genetics.

[31]  M. Heijer,et al.  Accurate, high-throughput typing of copy number variation using paralogue ratios from dispersed repeats. , 2007, Nucleic acids research.