Hemochromatosis risk genotype is not associated with colorectal cancer or age at its diagnosis

[1]  K. Kowdley,et al.  ACG Clinical Guideline: Hereditary Hemochromatosis , 2019, The American journal of gastroenterology.

[2]  Scott T. Weiss,et al.  Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations , 2019, bioRxiv.

[3]  S. Głuszek,et al.  The Influence of Red Meat on Colorectal Cancer Occurrence Is Dependent on the Genetic Polymorphisms of S-Glutathione Transferase Genes , 2019, Nutrients.

[4]  P. Elliott,et al.  Associations of genetically determined iron status across the phenome: A mendelian randomization study , 2019, PLoS medicine.

[5]  Stephanie A. Bien,et al.  Novel Common Genetic Susceptibility Loci for Colorectal Cancer , 2018, Journal of the National Cancer Institute.

[6]  Y. Chawla,et al.  Adult onset hereditary hemochromatosis is associated with a novel recurrent Hemojuvelin (HJV) gene mutation in north Indians. , 2018, Blood cells, molecules & diseases.

[7]  Mathieu Lemire,et al.  Discovery of common and rare genetic risk variants for colorectal cancer , 2018, Nature Genetics.

[8]  Lungen Lu,et al.  Non-HFE mutations in haemochromatosis in China: combination of heterozygous mutations involving HJV signal peptide variants , 2018, Journal of Medical Genetics.

[9]  C. Flowers,et al.  Colorectal cancer screening for average‐risk adults: 2018 guideline update from the American Cancer Society , 2018, CA: a cancer journal for clinicians.

[10]  David Lieberman,et al.  Colorectal Cancer Screening: Recommendations for Physicians and Patients from the U.S. Multi-Society Task Force on Colorectal Cancer , 2017, The American Journal of Gastroenterology.

[11]  S. Gruber,et al.  Targeted sequencing of established and candidate colorectal cancer genes in the Colon Cancer Family Registry Cohort , 2017, Oncotarget.

[12]  H. Kawabata The mechanisms of systemic iron homeostasis and etiology, diagnosis, and treatment of hereditary hemochromatosis , 2017, International Journal of Hematology.

[13]  X. Causse,et al.  Rare HFE variants are the most frequent cause of hemochromatosis in non‐c282y homozygous patients with hemochromatosis , 2016, American journal of hematology.

[14]  M. Phipps,et al.  Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement. , 2016, JAMA.

[15]  Rui-Xi Hua,et al.  The risk of new‐onset cancer associated with HFE C282Y and H63D mutations: evidence from 87,028 participants , 2016, Journal of cellular and molecular medicine.

[16]  Agnes S. Sundaresan,et al.  Penetrance of Hemochromatosis in HFE Genotypes Resulting in p.Cys282Tyr and p.[Cys282Tyr];[His63Asp] in the eMERGE Network , 2015, American journal of human genetics.

[17]  Christopher P. Fischer,et al.  Genome-wide association study of colorectal cancer identifies six new susceptibility loci , 2015, Nature Communications.

[18]  N. Naud,et al.  A central role for heme iron in colon carcinogenesis associated with red meat intake. , 2015, Cancer research.

[19]  A. Agudo,et al.  Iron and Cancer Risk—A Systematic Review and Meta-analysis of the Epidemiological Evidence , 2013, Cancer Epidemiology, Biomarkers & Prevention.

[20]  H. Yao,et al.  HFE gene C282Y variant is associated with colorectal cancer in Caucasians: a meta-analysis , 2013, Tumor Biology.

[21]  Simon G. Coetzee,et al.  Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis. , 2013, Gastroenterology.

[22]  P. Romundstad,et al.  Cancer risk in HFE C282Y homozygotes: results from the HUNT 2 study , 2013, Scandinavian journal of gastroenterology.

[23]  D. Swinkels,et al.  Diagnosis and management of hereditary haemochromatosis , 2011, BMJ : British Medical Journal.

[24]  P. Paluszkiewicz,et al.  Risk of colorectal cancer in relation to frequency and total amount of red meat consumption. Systematic review and meta-analysis , 2010, Archives of medical science : AMS.

[25]  D. English,et al.  HFE C282Y homozygotes are at increased risk of breast and colorectal cancer , 2010, Hepatology.

[26]  K. Hveem,et al.  Screening for C282Y homozygosity in a Norwegian population (HUNT2): The sensitivity and specificity of transferrin saturation , 2010, Scandinavian Journal of Clinical and Laboratory Investigation.

[27]  D. English,et al.  Iron-overload-related disease in HFE hereditary hemochromatosis. , 2008, The New England journal of medicine.

[28]  John D Potter,et al.  Colon Cancer Family Registry: An International Resource for Studies of the Genetic Epidemiology of Colon Cancer , 2007, Cancer Epidemiology Biomarkers & Prevention.

[29]  R. Hultcrantz,et al.  Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives. , 2003, Gastroenterology.

[30]  Christopher F. Martin,et al.  Association between hemochromatosis (HFE) gene mutation carrier status and the risk of colon cancer. , 2003, Journal of the National Cancer Institute.

[31]  C. McLaren,et al.  Population screening for hemochromatosis: A comparison of unbound iron‐binding capacity, transferrin saturation, and C282Y genotyping in 5,211 voluntary blood donors , 2000, Hepatology.

[32]  M. Thun,et al.  Validity of self-reported cancers in a prospective cohort study in comparison with data from state cancer registries. , 1998, American journal of epidemiology.

[33]  Jennifer J. Pointon,et al.  Global prevalence of putative haemochromatosis mutations. , 1997, Journal of medical genetics.

[34]  M. C. Ellis,et al.  A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis , 1996, Nature Genetics.

[35]  D. Häussinger,et al.  Long-term survival in patients with hereditary hemochromatosis. , 1996, Gastroenterology.

[36]  W. Willett,et al.  Validation of questionnaire information on risk factors and disease outcomes in a prospective cohort study of women. , 1986, American journal of epidemiology.