Implementation of non-insulin-dependent diabetes self-management education (DSME) in LMICs: a systematic review of cost, adoption, acceptability, and fidelity in resource-constrained settings

Background Type II diabetes (T2D), is a serious health issue accounting for 10.7% of mortality globally. 80% of cases worldwide are found in low- and middle-income countries (LMIC), with rapidly increasing prevalence. Diabetes-self management education (DSME) is a cost-effective program that provides at-risk individuals with the knowledge and skills they need to adopt lifestyle changes that will improve their health and well-being. This systematic review examined the application of DSME in LMICs and identified the corresponding implementation results (cost, fidelity, acceptance, and adoption) associated with successful implementation in low-resource settings. Methods and analysis The available research on T2D and the use of DSME in LMIC were systematically searched for using six electronic databases (PubMed, Embase, Cochrane, Web of Science, Google Scholar, PAIS, and EBSCO Discovery) between the months of October and November of 2022. The articles that met the search criteria were subsequently imported into EndNote and Covidence for analysis. The Cochrane RoB methodology for randomized trials was used to evaluate the risk of bias (RoB) in the included studies. A narrative synthesis was used to summarize the results. Results A total of 773 studies were imported for screening, after 203 duplicates were removed, 570 remained. Abstract and title screenings resulted in the exclusion of 487 articles, leaving 83 for full-text review. Following a full-text review, 76 articles were excluded and seven were found to be relevant to our search. The most common reasons for exclusion were study design (n = 23), lack of results (n = 14), and wrong patient population (n = 12). Conclusion Our systemic review found that DSME can be an acceptable and cost-effective solution in LMIC. While we intended to analyze cost, adoption, acceptability, and fidelity, our investigation revealed a gap in the literature on those areas, with most studies focusing on acceptability and cost and no studies identifying fidelity or adoption. To further evaluate the efficacy of DSME and enhance health outcomes for T2D in LMICs, more research is needed on its application. Systematic Review Registration osf.io/7482t.

[1]  D. Grobbee,et al.  Structured diabetes self‐management education and glycaemic control in low‐ and middle‐income countries: A systematic review , 2022, Diabetic medicine : a journal of the British Diabetic Association.

[2]  K. Khunti,et al.  EXTending availability of self-management structured EducatioN programmes for people with type 2 Diabetes in low-to-middle income countries (EXTEND)—a feasibility study in Mozambique and Malawi , 2021, BMJ Open.

[3]  Adam Fusheini,et al.  Diabetes self-management education interventions in the WHO African Region: A scoping review , 2021, PloS one.

[4]  M. Atif,et al.  Impact of pharmacist-led interventions on diabetes management at a community pharmacy in Pakistan: A quasi-experimental study. , 2021, JPMA. The Journal of the Pakistan Medical Association.

[5]  K. Sowjanya,et al.  Pharmacist led intervention towards management of type 2 diabetes mellitus and assessment of patient satisfaction of care - A prospective, randomized controlled study. , 2021, Diabetes & metabolic syndrome.

[6]  D. Labadarios,et al.  The state of diabetes treatment coverage in 55 low-income and middle-income countries: a cross-sectional study of nationally representative, individual-level data in 680 102 adults. , 2021, The Lancet. Healthy longevity.

[7]  Osei Sarfo-Kantanka,et al.  Pilot Mobile Phone Intervention in Promoting Type 2 Diabetes Management in an Urban Area in Ghana: A Randomized Controlled Trial , 2020, The Diabetes educator.

[8]  S. Shorey,et al.  Patients’ and healthcare professionals’ perspectives towards technology-assisted diabetes self-management education. A qualitative systematic review , 2020, PloS one.

[9]  F. Karachaliou,et al.  The Challenges in the Development of Diabetes Prevention and Care Models in Low-Income Settings , 2020, Frontiers in Endocrinology.

[10]  A. Moen,et al.  Diabetes Self-Management Education (DSME) – Effect on Knowledge, Self-Care Behavior, and Self-Efficacy Among Type 2 Diabetes Patients in Ethiopia: A Controlled Clinical Trial , 2019, Diabetes, metabolic syndrome and obesity : targets and therapy.

[11]  A. Ajayi,et al.  Efficacy, acceptability and feasibility of daily text-messaging in promoting glycaemic control and other clinical outcomes in a low-resource setting of South Africa: A randomised controlled trial , 2019, PloS one.

[12]  R. Govender,et al.  Epidemiology of Type 2 Diabetes – Global Burden of Disease and Forecasted Trends , 2019, Journal of epidemiology and global health.

[13]  G. Roglić,et al.  Implications of the growing burden of diabetes for premature cardiovascular disease mortality and the attainment of the Sustainable Development Goal target 3.4. , 2019, Cardiovascular diagnosis and therapy.

[14]  Benjamin M. Onyango,et al.  The Rise of Noncommunicable Diseases in Kenya: An Examination of the Time Trends and Contribution of the Changes in Diet and Physical Inactivity , 2018, Journal of epidemiology and global health.

[15]  D. Opoku,et al.  Self-management of diabetes in Sub-Saharan Africa: a systematic review , 2018, BMC Public Health.

[16]  S. Bull,et al.  Characteristics of mobile phone access and usage in rural and urban Guatemala: assessing feasibility of text message reminders to increase childhood immunizations. , 2018, mHealth.

[17]  Stephen H. Bell,et al.  A ?scoping review. , 2018, Sexual health.

[18]  E. Mohammadi,et al.  Barriers and facilitators related to the implementation of a physiological track and trigger system: A systematic review of the qualitative evidence , 2017, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[19]  K. Thankappan,et al.  Cultural adaptation of a peer-led lifestyle intervention program for diabetes prevention in India: the Kerala diabetes prevention program (K-DPP) , 2017, BMC Public Health.

[20]  M. Marschollek,et al.  SMS education for the promotion of diabetes self-management in low & middle income countries: a pilot randomized controlled trial in Egypt , 2017, BMC Public Health.

[21]  4. Lifestyle Management: Standards of Medical Care in Diabetes—2018 , 2017, Diabetes Care.

[22]  D. Prabhakaran,et al.  Cardiovascular, respiratory, and related disorders , 2017 .

[23]  D. Prabhakaran,et al.  Disease Control Priorities, Third Edition (Volume 5): Cardiovascular, Respiratory, and Related Disorders , 2017 .

[24]  L. K. Bartholomew,et al.  Persian Diabetes Self-Management Education (PDSME) program: evaluation of effectiveness in Iran. , 2016, Health promotion international.

[25]  A. Deaton,et al.  Understanding and Misunderstanding Randomized Controlled Trials , 2016, Social science & medicine.

[26]  Y. Ko,et al.  Economic evaluations of pharmacist‐managed services in people with diabetes mellitus: a systematic review , 2016, Diabetic medicine : a journal of the British Diabetic Association.

[27]  R. Colagiuri,et al.  The global response to diabetes: action or apathy? , 2014, The Medical journal of Australia.

[28]  Yoshimasa Tanaka,et al.  Risk Factors Contributing to Type 2 Diabetes and Recent Advances in the Treatment and Prevention , 2014, International journal of medical sciences.

[29]  J. Shaw,et al.  Global estimates of diabetes prevalence for 2013 and projections for 2035. , 2014, Diabetes Research and Clinical Practice.

[30]  F. Wolf Standards of Medical Care in Diabetes—2014 , 2013, Diabetes Care.

[31]  C. Ukwe,et al.  Cost-Utility Analysis of Pharmaceutical Care Intervention Versus Usual Care in Management of Nigerian Patients with Type 2 Diabetes. , 2013, Value in health regional issues.

[32]  A. Bianco,et al.  Type 2 Diabetes Family Histories, Body Composition and Fasting Glucose Levels: A Cross-Section Analysis in Healthy Sedentary Male and Female , 2013, Iranian journal of public health.

[33]  V. Basevi,et al.  Standards of Medical Care in Diabetes—2012 , 2011, Diabetes Care.

[34]  A. Rashidian,et al.  Patients’ Perspectives on Factors that Influence Diabetes Self-Care , 2011, Iranian journal of public health.

[35]  Frank B. Hu,et al.  Globalization of Diabetes , 2011, Diabetes Care.

[36]  Alicia C. Bunger,et al.  Outcomes for Implementation Research: Conceptual Distinctions, Measurement Challenges, and Research Agenda , 2010, Administration and Policy in Mental Health and Mental Health Services Research.

[37]  M. Peyrot,et al.  Aade Position Statement , 2008 .

[38]  A. Sanabria,et al.  Randomized controlled trial. , 2005, World journal of surgery.

[39]  Alan Bryman,et al.  Integrating quantitative and qualitative research , 2004 .

[40]  C. Florkowski,et al.  Noninsulin dependent diabetes mellitus. , 1993, The New Zealand medical journal.

[41]  R. J. Inglis Maturity-onset diabetes. , 1979, British medical journal.

[42]  Guillermo I Carrillo,et al.  A Controlled Clinical Trial , 2015 .

[43]  F. Hu,et al.  The role of diet, lifestyle, and genes , 2011 .

[44]  A. Casebeer,et al.  Broadening horizons: Integrating quantitative and qualitative research. , 1997, The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses.