Increased nitric oxide in nasal lavage fluid and nitrotyrosine formation in nasal mucosa — indices for severe perennial nasal allergy

The nose contributes the large amount of nitric oxide (NO) to exhaled air. NO is a mediator of vasodilation and yields peroxynitrite (ONOO−) by reacting with superoxide (O−2). ONOO− attacks tyrosine residues to form nitrotyrosine.

[1]  K. Ichimori,et al.  Clinical evidence of peroxynitrite formation in chronic renal failure patients with septic shock. , 1997, Free radical biology & medicine.

[2]  B. Kalyanaraman,et al.  Characterization of Sulfur-centered Radical Intermediates Formed during the Oxidation of Thiols and Sulfite by Peroxynitrite , 1996, The Journal of Biological Chemistry.

[3]  H. Ohshima,et al.  Formation of 8‐nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination , 1995, FEBS letters.

[4]  L. Gustafsson,et al.  Contribution from upper and lower airways to exhaled endogenous nitric oxide in humans , 1995, Acta anaesthesiologica Scandinavica.

[5]  T. Hökfelt,et al.  High nitric oxide production in human paranasal sinuses , 1995, Nature Medicine.

[6]  J. V. van Amsterdam,et al.  Nitric oxide metabolites in nasal lavage fluid of patients with house dust mite allergy. , 1995, Thorax.

[7]  J. Beckman,et al.  Quantitation of Protein Tyrosine, 3-Nitrotyrosine, and 3-Aminotyrosine Utilizing HPLC and Intrinsic Ultrviolet Absorbance , 1995 .

[8]  Evidence for in vivo peroxynitrite production in human acute lung injury. , 1995, American journal of respiratory and critical care medicine.

[9]  R. Radi,et al.  Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide. , 1994, The Journal of biological chemistry.

[10]  Carl Nathan,et al.  Nitric oxide synthases: Roles, tolls, and controls , 1994, Cell.

[11]  H. Esumi,et al.  Nitric oxide synthase-immunoreactive nerve fibers in the nasal mucosa of the rat , 1994, Brain Research.

[12]  Barry Halliwell,et al.  Evidence for nitric oxide‐mediated oxidative damage in chronic inflammation Nitrotyrosine in serum and synovial fluid from rheumatoid patients , 1994, FEBS letters.

[13]  J. Bousquet,et al.  Heterogeneous spontaneous and interleukin‐4–induced nitric oxide production by human monocytes , 1994, Journal of leukocyte biology.

[14]  M. Nakane,et al.  Nitric oxide synthase isozymes. Characterization, purification, molecular cloning, and functions. , 1994, Hypertension.

[15]  P G Anderson,et al.  Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry. , 1994, Biological chemistry Hoppe-Seyler.

[16]  P. J. Barnes,et al.  Increased nitric oxide in exhaled air of asthmatic patients , 1994, The Lancet.

[17]  Koichii Tanaka,et al.  Distribution of NADPH-diaphorase positive nerve fibers in the rat nasal mucosa , 1993, Neuroscience Letters.

[18]  S. Padmaja,et al.  The reaction of no with superoxide. , 1993, Free radical research communications.

[19]  J S Beckman,et al.  Peroxynitrite formation from macrophage-derived nitric oxide. , 1992, Archives of biochemistry and biophysics.

[20]  J S Beckman,et al.  Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. , 1992, Archives of biochemistry and biophysics.

[21]  D. Laskin,et al.  Production of nitric oxide by murine bone marrow cells. Inverse correlation with cellular proliferation. , 1992, Journal of immunology.

[22]  K. Rockett,et al.  Elevated secretion of reactive nitrogen and oxygen intermediates by inflammatory leukocytes in hyperacute experimental autoimmune encephalomyelitis: enhancement by the soluble products of encephalitogenic T cells , 1992, The Journal of experimental medicine.

[23]  S. Durham,et al.  Cytokine messenger RNA expression for IL-3, IL-4, IL-5, and granulocyte/macrophage-colony-stimulating factor in the nasal mucosa after local allergen provocation: relationship to tissue eosinophilia. , 1992, Journal of immunology.

[24]  A. Peitzman,et al.  Nitrogen oxide levels in patients after trauma and during sepsis. , 1991, Annals of surgery.

[25]  S. Moncada,et al.  Nitric oxide: physiology, pathophysiology, and pharmacology. , 1991, Pharmacological reviews.

[26]  B. Freeman,et al.  Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide. , 1991, The Journal of biological chemistry.

[27]  K. Chung,et al.  Stimulation of degranulation from human eosinophils by platelet-activating factor. , 1989, Journal of immunology.

[28]  S. Weiss.  Tissue destruction by neutrophils. , 1989, The New England journal of medicine.

[29]  S. Moncada,et al.  Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor , 1987, Nature.

[30]  S. Tannenbaum,et al.  Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. , 1982, Analytical biochemistry.

[31]  S. Pincus,et al.  Superoxide production by eosinophils: activation by histamine. , 1982, The Journal of investigative dermatology.

[32]  T. Kamada,et al.  Hemoperfusion, rate of oxygen consumption and redox levels of mitochondrial cytochrome c (+c1) in liver in situ of anesthetized rat measured by reflectance spectrophotometry. , 1981, Biochimica et biophysica acta.

[33]  M. Ui,et al.  An ultrasensitive method for the simultaneous determination of cyclic AMP and cyclic GMP in small-volume samples from blood and tissue. , 1977, Biochemical medicine.

[34]  E B Kern,et al.  The human nasal cycle. , 1977, Mayo Clinic proceedings.

[35]  K. Austen.  Reaction mechanisms in the release of mediators of immediate hypersensitivity from human lung tissue. , 1974, Federation proceedings.

[36]  C. H. Keith,et al.  Nitrogen Oxides in Tobacco Smoke , 1965, Nature.