Experimental comparison between speckle and grating-based imaging technique using synchrotron radiation X-rays.

X-ray phase contrast and dark-field imaging techniques provide important and complementary information that is inaccessible to the conventional absorption contrast imaging. Both grating-based imaging (GBI) and speckle-based imaging (SBI) are able to retrieve multi-modal images using synchrotron as well as lab-based sources. However, no systematic comparison has been made between the two techniques so far. We present an experimental comparison between GBI and SBI techniques with synchrotron radiation X-ray source. Apart from the simple experimental setup, we find SBI does not suffer from the issue of phase unwrapping, which can often be problematic for GBI. In addition, SBI is also superior to GBI since two orthogonal differential phase gradients can be simultaneously extracted by one dimensional scan. The GBI has less stringent requirements for detector pixel size and transverse coherence length when a second or third grating can be used. This study provides the reference for choosing the most suitable technique for diverse imaging applications at synchrotron facility.

[1]  O. Bunk,et al.  Hard x-ray phase tomography with low-brilliance sources. , 2007, Physical review letters.

[2]  C. David,et al.  At-wavelength characterization of refractive x-ray lenses using a two-dimensional grating interferometer , 2011 .

[3]  Emilio Quaia,et al.  Mammography with synchrotron radiation: first clinical experience with phase-detection technique. , 2011, Radiology.

[4]  David M. Paganin,et al.  X-ray phase imaging with a paper analyzer , 2012 .

[5]  Kawal Sawhney,et al.  Speckle based X-ray wavefront sensing with nanoradian angular sensitivity. , 2015, Optics express.

[6]  Atsushi Momose,et al.  Phase–contrast X–ray computed tomography for observing biological soft tissues , 1996, Nature Medicine.

[7]  O. Bunk,et al.  Phase retrieval and differential phase-contrast imaging with low-brilliance X-ray sources , 2006 .

[8]  P. Cloetens,et al.  Holotomography: Quantitative phase tomography with micrometer resolution using hard synchrotron radiation x rays , 1999 .

[9]  Atsushi Momose,et al.  High-speed X-ray phase imaging and X-ray phase tomography with Talbot interferometer and white synchrotron radiation. , 2009, Optics express.

[10]  Kawal Sawhney,et al.  A Test Beamline on Diamond Light Source , 2010 .

[11]  Franz Pfeiffer,et al.  X-ray phase imaging with a grating interferometer. , 2005, Optics express.

[12]  R. Atwood,et al.  X-ray phase contrast tomography by tracking near field speckle , 2015, Scientific reports.

[13]  O. Bunk,et al.  A two-directional approach for grating based differential phase contrast imaging using hard x-rays. , 2007, Optics express.

[14]  Franz Pfeiffer,et al.  Emphysema diagnosis using X-ray dark-field imaging at a laser-driven compact synchrotron light source , 2012, Proceedings of the National Academy of Sciences.

[15]  Kawal Sawhney,et al.  Hard-X-ray directional dark-field imaging using the speckle scanning technique. , 2015, Physical review letters.

[16]  E Brun,et al.  High-resolution breast tomography at high energy: a feasibility study of phase contrast imaging on a whole breast , 2012, Physics in medicine and biology.

[17]  Xie Huimin,et al.  Performance of sub-pixel registration algorithms in digital image correlation , 2006 .

[18]  Kejun Kang,et al.  Quantitative grating-based x-ray dark-field computed tomography , 2009 .

[19]  P Thibault,et al.  Unwrapping differential x-ray phase-contrast images through phase estimation from multiple energy data. , 2013, Optics express.

[20]  Franz Pfeiffer,et al.  Multimodal hard X-ray imaging of a mammography phantom at a compact synchrotron light source. , 2012, Journal of synchrotron radiation.

[21]  Timm Weitkamp,et al.  Two-dimensional x-ray grating interferometer. , 2010, Physical review letters.

[22]  Paola Coan,et al.  X-ray phase-contrast imaging: from pre-clinical applications towards clinics , 2013, Physics in medicine and biology.

[23]  Kawal Sawhney,et al.  Advanced in situ metrology for x-ray beam shaping with super precision. , 2015, Optics express.

[24]  A Bravin,et al.  Analytical and experimental determination of signal-to-noise ratio and figure of merit in three phase-contrast imaging techniques. , 2012, Optics express.

[25]  P. C. Diemoz,et al.  Theoretical comparison of three X-ray phase-contrast imaging techniques: propagation-based imaging, analyzer-based imaging and grating interferometry. , 2012, Optics express.

[26]  Sebastien Berujon,et al.  X-ray multimodal imaging using a random-phase object , 2012 .

[27]  Kawal Sawhney,et al.  From synchrotron radiation to lab source: advanced speckle-based X-ray imaging using abrasive paper , 2016, Scientific Reports.

[28]  C. David,et al.  Differential x-ray phase contrast imaging using a shearing interferometer , 2002 .

[29]  Alessandro Olivo,et al.  Proof-of-concept demonstration of edge-illumination x-ray phase contrast imaging combined with tomosynthesis , 2014, Physics in medicine and biology.

[30]  S. Wilkins,et al.  Phase-contrast imaging of weakly absorbing materials using hard X-rays , 1995, Nature.

[31]  Eric Ziegler,et al.  Two-dimensional x-ray beam phase sensing. , 2012, Physical review letters.

[32]  Two dimensional x-ray phase imaging using single grating interferometer with embedded x-ray targets. , 2015, Optics express.

[33]  Ashley F. Stein,et al.  Single-shot x-ray differential phase-contrast and diffraction imaging using two-dimensional transmission gratings. , 2010, Optics letters.

[34]  F. Pfeiffer,et al.  Experimental comparison of grating- and propagation-based hard X-ray phase tomography of soft tissue , 2014 .

[35]  A Bravin,et al.  High-resolution brain tumor visualization using three-dimensional x-ray phase contrast tomography , 2007, Physics in medicine and biology.

[36]  F. Pfeiffer,et al.  Speckle-based x-ray phase-contrast and dark-field imaging with a laboratory source. , 2014, Physical review letters.