论文信息 - Transient neutropenia in normal donors after G‐CSF mobilization and stem cell apheresis

Transient neutropenia in normal donors after G‐CSF mobilization and stem cell apheresis

Thirteen normal adult donors underwent daily leukapheresis for peripheral blood progenitor cell collection for allografting beginning on day 4 or 5 of G‐CSF mobilization (12 μg/kg/d). They had complete blood counts performed 7–10 d after the completion of the procedure. A reduction in the total leucocyte count below baseline levels, accounted for by a decrease in the absolute neutrophil (ANC) and lymphocyte counts, was noted. Neutropenia (ANC < 1.5 × 109/l) occurred in two (15%) of the donors. The lowest ANC observed was 0.6 × 109/l. The neutropenia was asymptomatic and resolved on follow‐up evaluation.

P. Anderlini | M. Körbling | D. Przepiorka | R. Champlin | D. Seong

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