DNA-Encoded Library Screening To Inform Design of a Ribonuclease Targeting Chimera (RiboTAC).
暂无分享,去创建一个
M. Disney | A. Adibekian | M. Cameron | D. Abegg | Toru Tanaka | Jared T. Baisden | Patrick R. A. Zanon | Yoshihiro Akahori | Xueyi Yang | Samantha M. Meyer | Zainab Alshakarchi
[1] Jessica L. Childs-Disney,et al. Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA. , 2022, Journal of the American Chemical Society.
[2] Jessica L. Childs-Disney,et al. Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment. , 2021, Journal of the American Chemical Society.
[3] A. Keefe,et al. Bispecific Estrogen Receptor α Degraders Incorporating Novel Binders Identified Using DNA-Encoded Chemical Library Screening. , 2021, Journal of medicinal chemistry.
[4] A. Ciulli,et al. E3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones , 2020, SLAS discovery : advancing life sciences R & D.
[5] M. Baud,et al. Current strategies for the design of PROTAC linkers: a critical review , 2020, Exploration of targeted anti-tumor therapy.
[6] R. Silverman,et al. A phenolic small molecule inhibitor of RNase L prevents cell death from ADAR1 deficiency , 2020, Proceedings of the National Academy of Sciences.
[7] R. Langer,et al. Advances in oligonucleotide drug delivery , 2020, Nature Reviews Drug Discovery.
[8] Jonathan L Chen,et al. Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. , 2020, Journal of the American Chemical Society.
[9] Eric T. Wang,et al. Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer , 2020, Proceedings of the National Academy of Sciences.
[10] C. Crews,et al. Proteolysis-Targeting Chimeras as Therapeutics and Tools for Biological Discovery , 2020, Cell.
[11] John A. Tallarico,et al. Harnessing the Anti-Cancer Natural Product Nimbolide for Targeted Protein Degradation , 2018, bioRxiv.
[12] B. Cravatt,et al. Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16 , 2018, bioRxiv.
[13] Hafeez S Haniff,et al. Approved Anti-cancer Drugs Target Oncogenic Non-coding RNAs. , 2018, Cell chemical biology.
[14] M. Disney,et al. Small Molecule Targeted Recruitment of a Nuclease to RNA. , 2018, Journal of the American Chemical Society.
[15] G. Varani,et al. A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing. , 2017, ACS chemical biology.
[16] Sydney Brenner,et al. DNA-Encoded Compound Libraries as Open Source: A Powerful Pathway to New Drugs. , 2017, Angewandte Chemie.
[17] C. Tsao,et al. Emerging role of microRNA-21 in cancer (Review) , 2016 .
[18] S. L. Le Grice,et al. Identification of Biologically Active, HIV TAR RNA-Binding Small Molecules Using Small Molecule Microarrays , 2014, Journal of the American Chemical Society.
[19] J. Donovan,et al. Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response , 2014, Science.
[20] Steven M. Gallo,et al. Sequence-based design of bioactive small molecules that target precursor microRNAs , 2014, Nature chemical biology.
[21] Y. Yen,et al. Dovitinib synergizes with oxaliplatin in suppressing cell proliferation and inducing apoptosis in colorectal cancer cells regardless of RAS-RAF mutation status , 2014, Molecular Cancer.
[22] M. Disney,et al. Covalent small-molecule-RNA complex formation enables cellular profiling of small-molecule-RNA interactions. , 2013, Angewandte Chemie.
[23] Dario Neri,et al. 20 years of DNA-encoded chemical libraries. , 2011, Chemical communications.
[24] I. Andricioaei,et al. Discovery of selective bioactive small molecules by targeting an RNA dynamic ensemble. , 2011, Nature chemical biology.
[25] Yan Zhang,et al. Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth , 2011, Breast Cancer Research.
[26] Anna M. Krichevsky,et al. miR-21: a small multi-faceted RNA , 2008, Journal of cellular and molecular medicine.
[27] Matthew D Disney,et al. Two-dimensional combinatorial screening identifies specific aminoglycoside-RNA internal loop partners. , 2008, Journal of the American Chemical Society.
[28] Shuomin Zhu,et al. MicroRNA-21 targets tumor suppressor genes in invasion and metastasis , 2008, Cell Research.
[29] R. Silverman,et al. Hepatitis C virus RNA: dinucleotide frequencies and cleavage by RNase L. , 2007, Virus research.
[30] R. Silverman,et al. Small-molecule activators of RNase L with broad-spectrum antiviral activity , 2007, Proceedings of the National Academy of Sciences.
[31] N. Greenfield. Using circular dichroism spectra to estimate protein secondary structure , 2007, Nature Protocols.