Recent Advances of α‐Isothiocyanato Compounds in the Catalytic Asymmetric Reaction

[1]  Lili Lin,et al.  Asymmetric Synthesis of Spirocyclic Oxindole‐Fused Tetrahydrothiophenes via N,N′‐Dioxide–Nickel(II) Catalyzed Domino Reaction of 1,4‐Dithiane‐2,5‐diol with 3‐Alkenyloxindoles , 2015 .

[2]  Xiaomei Zhang,et al.  Quinine-catalyzed asymmetric domino Mannich-cyclization reactions of 3-isothiocyanato oxindoles with imines for the synthesis of spirocyclic oxindoles , 2015 .

[3]  Maria M. M. Santos.  Recent advances in the synthesis of biologically active spirooxindoles , 2014 .

[4]  Jian Zhou,et al.  Asymmetric triple relay catalysis: enantioselective synthesis of spirocyclic indolines through a one-pot process featuring an asymmetric 6π electrocyclization. , 2014, Angewandte Chemie.

[5]  Hong Liu,et al.  A Mannich/cyclization cascade process for the asymmetric synthesis of spirocyclic thioimidazolidineoxindoles. , 2014, Chemical communications.

[6]  Jian-Wu Xie,et al.  Organocatalytic domino Michael/cyclization reaction: efficient synthesis of multi-functionalized tetracyclic spirooxindoles with multiple stereocenters , 2014 .

[7]  S. Mukherjee,et al.  Catalytic Asymmetric Michael Addition/Cyclization Cascade Reaction of 3-Isothiocyanatooxindoles with Nitro Olefins , 2014 .

[8]  B. Kumar,et al.  Regioselective synthesis of polycyclic aza-oxa and aza-oxa-thia heteroarenes as Colo-205 and HepG2 carcinoma cells growth inhibitors. , 2014, European journal of medicinal chemistry.

[9]  Ying‐Chun Chen,et al.  Trienamine catalysis with linear deconjugated 3,5-dienones , 2014 .

[10]  W. Xiao,et al.  Enantioselective cascade Michael addition/cyclization reactions of 3-nitro-2H-chromenes with 3-isothiocyanato oxindoles: efficient synthesis of functionalized polycyclic spirooxindoles. , 2014, Chemistry.

[11]  Xiaomei Zhang,et al.  Quinine-Catalyzed Asymmetric Domino Michael-Cyclization Reaction for the Synthesis of Spirocyclic Oxindoles Bearing Two Spiro Quaternary Centers and Three Consecutive Stereocenters. , 2014 .

[12]  L. Mrówczyńska,et al.  Synthesis and haemolytic activity of novel salts made of nicotine alkaloids and bile acids. , 2014, Bioorganic & medicinal chemistry letters.

[13]  Yiming Cao,et al.  Catalytic asymmetric 1,2-addition of α-isothiocyanato phosphonates: synthesis of chiral β-hydroxy- or β-amino-substituted α-amino phosphonic acid derivatives. , 2014, Angewandte Chemie.

[14]  C. Barbas,et al.  Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies , 2014 .

[15]  Daniel M. Rotroff,et al.  Development of a thyroperoxidase inhibition assay for high-throughput screening. , 2014, Chemical research in toxicology.

[16]  S. Kim,et al.  4-Methylthio-butanyl derivatives from the seeds of Raphanus sativus and their biological evaluation on anti-inflammatory and antitumor activities. , 2014, Journal of ethnopharmacology.

[17]  M. Kanai,et al.  ENANTIOSELECTIVE SYNTHESIS OF SPIROOXINDOLES VIA DIRECT CATALYTIC ASYMMETRIC ALDOL-TYPE REACTION OF ISOTHIOCYANATO OXINDOLES (Dedicated to Professor Victor Snieckus on the occasion of his 77th birthday) , 2014 .

[18]  M. Heravi,et al.  Recent advances in C-heteroatom bond forming by asymmetric Michael addition , 2013, Molecular Diversity.

[19]  Jian Zhou,et al.  One-pot tandem approach to spirocyclic oxindoles featuring adjacent spiro-stereocenters. , 2013, Angewandte Chemie.

[20]  M. Shi,et al.  Enantioselective Synthesis of Spirooxindoles: Asymmetric [3+2] Cycloaddition of (3-Isothiocyanato)oxindoles with Azodicarboxylates , 2013 .

[21]  Lili Lin,et al.  Chiral N,N′‐Dioxide–Yttrium Triflate Complexes‐Catalyzed Asymmetric Aldol Cyclization of α‐Keto Esters with α‐Isothiocyanato Imide , 2013 .

[22]  Xiaomei Zhang,et al.  Asymmetric synthesis of β-hydroxy-α-amino phosphonic acid derivatives via organocatalytic direct aldol reaction of α-isothiocyanato phosphonates with aldehydes. , 2013, The Journal of organic chemistry.

[23]  D. Enders,et al.  Recent Advances in Metal-Catalyzed Asymmetric Mannich Reactions , 2013, Synthesis.

[24]  B. Haertel,et al.  Investigations on synthesis and structure elucidation of novel [1,2,4]triazolo[1,2-a]pyridazine-1-thiones and their inhibitory activity against inducible nitric oxide synthase. , 2013, Bioorganic & medicinal chemistry.

[25]  L. Verschaeve,et al.  Synthesis and antimycobacterial activity of analogues of the bioactive natural products sampangine and cleistopholine. , 2013, European journal of medicinal chemistry.

[26]  M. Shi,et al.  Enantioselective Construction of Spirooxindole Derivatives: Asymmetric [3+2] Cyclization of Isothiocyanatooxindoles with Allenic Esters or 2‐Butynedioic Acid Diesters , 2013 .

[27]  M. Kanai,et al.  Catalytic asymmetric synthesis of spirooxindoles via addition of isothiocyanato oxindoles to aldehydes under dinuclear nickel Schiff base catalysis. , 2013, Chemistry, an Asian journal.

[28]  Yiming Cao,et al.  Catalytic enantioselective ring-opening reaction of meso-aziridines with α-isothiocyanato imides. , 2013, Chemistry.

[29]  Xiaomei Zhang,et al.  Highly efficient synthesis of spiro[oxazolidine-2-thione-oxindoles] with 3-isothiocyanato oxindoles and aldehydes via an organocatalytic cascade aldol-cyclization reaction , 2013 .

[30]  Jian Zhou,et al.  Highly stereoselective olefin cyclopropanation of diazooxindoles catalyzed by a C2-symmetric spiroketal bisphosphine/Au(I) complex. , 2013, Journal of the American Chemical Society.

[31]  Xiaomei Zhang,et al.  3-isothiocyanato oxindoles serving as powerful and versatile precursors to structurally diverse dispirocyclic thiopyrrolidineoxindoles through a cascade Michael/cyclization process with amino-thiocarbamate catalysts. , 2013, Chemistry.

[32]  Rui Wang,et al.  Recent Advances in Asymmetric Organocatalytic Construction of 3,3′‐Spirocyclic Oxindoles , 2013 .

[33]  W. Xiao,et al.  Highly Enantioselective Organocatalytic Michael Addition/Cyclization Cascade Reaction of Ylideneoxindoles with Isothiocyanato Oxindoles: A Formal [3+2] Cycloaddition Approach to Optically Active Bispirooxindole Derivatives , 2013 .

[34]  Xiaomei Zhang,et al.  Highly efficient and stereocontrolled construction of 3,3'-pyrrolidonyl spirooxindoles via organocatalytic domino Michael/cyclization reaction. , 2013, Organic letters.

[35]  Shoulei Wang,et al.  An asymmetric approach toward chiral multicyclic spirooxindoles from isothiocyanato oxindoles and unsaturated pyrazolones by a chiral tertiary amine thiourea catalyst. , 2013, Chemical communications.

[36]  Yong-mei Wang,et al.  Highly efficient enantioselective construction of bispirooxindoles containing three stereocenters through an organocatalytic cascade Michael-cyclization reaction. , 2013, Chemistry.

[37]  Yiming Cao,et al.  Catalytic asymmetric Michael addition/cyclization of isothiocyanato oxindoles: highly efficient and versatile approach for the synthesis of 3,2'-pyrrolidinyl mono- and bi-spirooxindole frameworks. , 2013, Chemistry.

[38]  Xianxing Jiang,et al.  Core scaffold-inspired stereoselective synthesis of spiropyrazolones via an organocatalytic Michael/cyclization sequence. , 2012, The Journal of organic chemistry.

[39]  S. Nayak,et al.  Organocatalytic tandem Michael addition reactions: A powerful access to the enantioselective synthesis of functionalized chromenes, thiochromenes and 1,2-dihydroquinolines , 2012, Beilstein journal of organic chemistry.

[40]  L. Spirikhin,et al.  N-sulfinylanilines as dienes in the Diels-Alder reaction. Structural aspects , 2012, Russian Journal of General Chemistry.

[41]  Thomas W. Linsky,et al.  Discovery of structurally-diverse inhibitor scaffolds by high-throughput screening of a fragment library with dimethylarginine dimethylaminohydrolase. , 2012, Bioorganic & medicinal chemistry.

[42]  A. Franz,et al.  Strategies for the enantioselective synthesis of spirooxindoles. , 2012, Organic & biomolecular chemistry.

[43]  M. Kanai,et al.  Catalytic asymmetric synthesis of spirooxindoles by a mannich-type reaction of isothiocyanato oxindoles. , 2012, Angewandte Chemie.

[44]  Yong Tang,et al.  Tris(oxazoline)/copper-catalyzed coupling of alkynes with nitrones: a highly enantioselective access to β-lactams , 2012 .

[45]  V. Singh,et al.  Enantioselective Organocatalytic Aldol Reaction Using Small Organic Molecules , 2012 .

[46]  W. Xiao,et al.  Development of cascade reactions for the concise construction of diverse heterocyclic architectures. , 2012, Accounts of chemical research.

[47]  H. Pellissier.  Recent Developments in Asymmetric Organocatalytic Domino Reactions , 2012 .

[48]  Xiaomei Zhang,et al.  Highly efficient and stereoselective construction of dispiro-[oxazolidine-2-thione]bisoxindoles and dispiro[imidazolidine-2-thione]bisoxindoles. , 2012, Organic letters.

[49]  C. Barbas,et al.  Core structure-based design of organocatalytic [3+2]-cycloaddition reactions: highly efficient and stereocontrolled syntheses of 3,3'-pyrrolidonyl spirooxindoles. , 2012, Chemistry.

[50]  Xianxing Jiang,et al.  Enantioselective Michael/cyclization reaction sequence: scaffold-inspired synthesis of spirooxindoles with multiple stereocenters. , 2011, Angewandte Chemie.

[51]  Lin He,et al.  N-Heterocyclic carbene catalysis: enantioselective formal [2+2] cycloaddition of ketenes and N-sulfinylanilines. , 2011, Angewandte Chemie.

[52]  Xianxing Jiang,et al.  Enantioselective Synthesis of Cyclic Thioureas via Mannich Reaction and Concise Synthesis of Highly Optically Active Methylthioimidazolines: Discovery of a More Potent Antipyretic Agent , 2011 .

[53]  C. Zhao,et al.  Organocatalytic enantioselective tandem aldol-cyclization reaction of α-isothiocyanato imides and activated carbonyl compounds. , 2011, Tetrahedron, asymmetry.

[54]  Lili Lin,et al.  Facile and efficient enantioselective hydroxyamination reaction: synthesis of 3-hydroxyamino-2-oxindoles using nitrosoarenes. , 2011, Angewandte Chemie.

[55]  S. Matsunaga,et al.  Stereodivergent direct catalytic asymmetric Mannich-type reactions of α-isothiocyanato ester with ketimines. , 2011, Angewandte Chemie.

[56]  Lin-feng Cun,et al.  Organocatalytic direct asymmetric aldol reactions of 3-isothiocyanato oxindoles to ketones: stereocontrolled synthesis of spirooxindoles bearing highly congested contiguous tetrasubstituted stereocenters. , 2011, Organic letters.

[57]  A. Molchanov,et al.  An efficient and stereoselective cycloaddition of C-aryl and C-amido nitrones to dimethyl 2-benzylidenecyclopropane-1,1-dicarboxylate , 2011 .

[58]  Lili Lin,et al.  Guanidine organocatalyst for the asymmetric Mannich-type reaction between α-isothiocyanato imide and sulfonyl imines. , 2011, Chemistry.

[59]  Dong Wang,et al.  Asymmetric organocatalytic N-nitroso-aldol reaction of oxindoles , 2010 .

[60]  H. Osman,et al.  Substituted spiro [2.3'] oxindolespiro [3.2″]-5,6-dimethoxy-indane-1″-one-pyrrolidine analogue as inhibitors of acetylcholinesterase. , 2010, Bioorganic & medicinal chemistry letters.

[61]  I. Guzei,et al.  Oxaziridine-mediated oxyamination of indoles: an approach to 3-aminoindoles and enantiomerically enriched 3-aminopyrroloindolines. , 2010, Angewandte Chemie.

[62]  Xianxing Jiang,et al.  A unique approach to the concise synthesis of highly optically active spirooxazolines and the discovery of a more potent oxindole-type phytoalexin analogue. , 2010, Journal of the American Chemical Society.

[63]  Lili Lin,et al.  Efficient synthesis of beta-hydroxy-alpha-amino acid derivatives via direct catalytic asymmetric aldol reaction of alpha-isothiocyanato imide with aldehydes. , 2010, Chemistry.

[64]  L. Gong,et al.  The role of double hydrogen bonds in asymmetric direct aldol reactions catalyzed by amino amide derivatives. , 2010, Chemical communications.

[65]  D. Seidel,et al.  Catalytic enantioselective aldol additions of alpha-isothiocyanato imides to alpha-ketoesters. , 2010, Chemical communications.

[66]  Jian Zhou,et al.  Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C‐3 Position , 2010 .

[67]  Prithvi Singh,et al.  A rationale for the activity profile of arylpiperazinylthioalkyls as 5-HT1A-serotonin and alpha1-adrenergic receptor ligands. , 2010, European journal of medicinal chemistry.

[68]  B. Trost,et al.  The direct catalytic asymmetric aldol reaction. , 2010, Chemical Society reviews.

[69]  Xianxing Jiang,et al.  Direct organocatalytic asymmetric aldol reaction of alpha-isothiocyanato imides to alpha-ketoesters under low ligand loading: a doubly stereocontrolled approach to cyclic thiocarbamates bearing chiral quaternary stereocenters. , 2010, Organic letters.

[70]  S. Matsunaga,et al.  Construction of contiguous tetrasubstituted chiral carbon stereocenters via direct catalytic asymmetric aldol reaction of alpha-isothiocyanato esters with ketones. , 2009, Journal of the American Chemical Society.

[71]  Zugui Shi,et al.  Organocatalytic Asymmetric Synthesis of Protected α,β‐Diamino Acids , 2009 .

[72]  D. Enders,et al.  Organocatalytic asymmetric aza-Michael additions. , 2009, Chemistry.

[73]  B. Trost,et al.  Asymmetric Syntheses of Oxindoleand Indole Spirocyclic Alkaloid Natural Products , 2009 .

[74]  Le Li,et al.  Catalytic enantioselective synthesis of alpha,beta-diamino acid derivatives. , 2009, Journal of the American Chemical Society.

[75]  T. Molinski,et al.  Synthesis and structure-activity relationships of bengazole A analogs. , 2009, Bioorganic & medicinal chemistry letters.

[76]  Minghui Yang,et al.  Chemical Genetic Profiling and Characterization of Small-molecule Compounds That Affect the Biosynthesis of Unsaturated Fatty Acids in Candida albicans* , 2009, Journal of Biological Chemistry.

[77]  Pinaki S. Bhadury,et al.  Synthesis and antiviral activities of chiral thiourea derivatives containing an alpha-aminophosphonate moiety. , 2009, Journal of agricultural and food chemistry.

[78]  F. Albericio,et al.  A convenient general method for synthesis of Nα‐ or Nω‐dithiasuccinoyl (Dts) amino acids and dipeptides: application of polyethylene glycol as a carrier for functional purification* , 2009 .

[79]  Le Li,et al.  Catalytic enantioselective aldol additions of alpha-isothiocyanato imides to aldehydes. , 2008, Journal of the American Chemical Society.

[80]  P. Yogeeswari,et al.  Discovery of antimycobacterial spiro-piperidin-4-ones: an atom economic, stereoselective synthesis, and biological intervention. , 2008, Journal of medicinal chemistry.

[81]  M. A. Ischay,et al.  Activation of N-sulfonyl oxaziridines using copper(II) catalysts: aminohydroxylations of styrenes and 1,3-dienes. , 2008, Journal of the American Chemical Society.

[82]  F. Rutjes,et al.  Organocatalysed asymmetric Mannich reactions. , 2008, Chemical Society reviews.

[83]  Karl A. Scheidt,et al.  Natürliche Pyrrolidinylspirooxindole als Vorlagen für die Entwicklung medizinischer Wirkstoffe , 2007 .

[84]  K. Scheidt,et al.  Pyrrolidinyl-spirooxindole natural products as inspirations for the development of potential therapeutic agents. , 2007, Angewandte Chemie.

[85]  M. Willis,et al.  Direct catalytic enantioselective mannich reactions : Synthesis of protected anti-α,β-diamino acids , 2007 .

[86]  Wei-Liang Duan,et al.  Palladium-catalyzed asymmetric [3+3] cycloaddition of trimethylenemethane derivatives with nitrones. , 2007, Angewandte Chemie.

[87]  A. Alexakis,et al.  Chiral amines as organocatalysts for asymmetric conjugate addition to nitroolefins and vinyl sulfones via enamine activation. , 2007, Chemical communications.

[88]  D. Alonso,et al.  Organocatalytic asymmetric conjugate additions , 2007 .

[89]  C. Shaffer,et al.  Copper(II)-catalyzed aminohydroxylation of olefins. , 2007, Journal of the American Chemical Society.

[90]  S. Matsunaga,et al.  Metal/linked-BINOL complexes: Applications in direct catalytic asymmetric Mannich-type reactions , 2006 .

[91]  John A. Robinson,et al.  An improved solid-phase methodology for the synthesis of putative hexa- and heptapeptide intermediates in vancomycin biosynthesis. , 2005, Organic & biomolecular chemistry.

[92]  Yi Zheng,et al.  Fe(II) and Co(II) pyridinebisimine complexes bearing different substituents on ortho- and para-position of imines : synthesis, characterization and behavior of ethylene polymerization , 2005 .

[93]  M. Willis,et al.  The Direct Catalytic Enantioselective Synthesis of Protected Aryl β‐Hydroxy‐α‐Amino Acids , 2005 .

[94]  S. Arai,et al.  Short synthesis of both enantiomers of cytoxazone using the Petasis reaction , 2004 .

[95]  F. Himo,et al.  The direct catalytic asymmetric alpha-aminooxylation reaction: development of stereoselective routes to 1,2-diols and 1,2-amino alcohols and density functional calculations. , 2004, Chemistry.

[96]  Hisashi Yamamoto,et al.  Design of acid-base catalysis for the asymmetric direct Aldol reaction. , 2004, Accounts of chemical research.

[97]  Junichiro Yamaguchi,et al.  Direct Proline-Catalyzed Asymmetricα-Aminoxylation of Ketones , 2004 .

[98]  Junichiro Yamaguchi,et al.  Direct Proline‐Catalyzed Asymmetric α‐Aminoxylation of Ketones , 2004 .

[99]  M. Kerr,et al.  A homo [3+2] dipolar cycloaddition: the reaction of nitrones with cyclopropanes. , 2003, Angewandte Chemie.

[100]  E. Carreira,et al.  Construction of Spiro[pyrrolidine‐3,3′‐oxindoles] − Recent Applications to the Synthesis of Oxindole Alkaloids , 2003 .

[101]  Robert M. Williams,et al.  Paraherquamides, brevianamides, and asperparalines: laboratory synthesis and biosynthesis. An interim report. , 2003, Accounts of chemical research.

[102]  S. Danishefsky,et al.  Eine chemische Denksportaufgabe: die Totalsynthese von Gelsemin , 2003 .

[103]  S. Danishefsky,et al.  Gelsemine: a thought-provoking target for total synthesis. , 2003, Angewandte Chemie.

[104]  S. Martin.  Evolution of the vinylogous Mannich reaction as a key construction for alkaloid synthesis. , 2002, Accounts of chemical research.

[105]  M. Seki,et al.  Facile Synthesis of (R)-4-Mercaptopyrrolidine-2-thione from L-Aspartic Acid , 2001, Bioscience, biotechnology, and biochemistry.

[106]  Chi-Huey Wong,et al.  Die katalysierte asymmetrische Aldolreaktion , 2000 .

[107]  Wong,et al.  The Catalytic Asymmetric Aldol Reaction. , 2000, Angewandte Chemie.

[108]  J. Barrow,et al.  Total Syntheses of Vancomycin and Eremomycin Aglycons. , 1998, Angewandte Chemie.

[109]  David A. Evans,et al.  TOTALSYNTHESE DES VANCOMYCIN- UND DES EREMOMYCIN-AGLYCONS , 1998 .

[110]  R. Pompei,et al.  Antifungal, antibacterial, antiviral and cytotoxic activity of novel thio- and seleno-azoles. , 1997, Pharmacological research.

[111]  J. Michael,et al.  Synthesis of (±)-Indolizidine 209B and a New 209B Diastereoisomer , 1996 .

[112]  A. Amarasekara,et al.  Reactions of N-sulfinylarylamines with 1,4-benzoquinone and 1,4-naphthoquinone: synthesis of N-aryl sulfinamoyl quinones and their hydrolysis to hydroxyquinones , 1995 .

[113]  J. Kehne,et al.  5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents. , 1994, Journal of medicinal chemistry.

[114]  U. Schmidt,et al.  Total Synthesis of the Biphenomycins; V.1 Synthesis of Biphenomycin A , 1992 .

[115]  U. Schmidt,et al.  The synthesis of biphenomycin B , 1991 .

[116]  Davidr . Evans,et al.  Synthesis of the cyclic hexapeptide echinocandin D. New approaches to the asymmetric synthesis of .beta.-hydroxy .alpha.-amino acids , 1987 .

[117]  Davidr . Evans,et al.  Asymmetric glycine enolate aldol reactions: synthesis of cyclosporin's unusual amino acid, MeBmt , 1986 .

[118]  A. S. Howard,et al.  Vinylogous urethanes in alkaloid synthesis: formal syntheses of Elaeocarpus alkaloids , 1980 .

[119]  A. Michael.  Ueber die Addition von Natriumacetessig‐ und Natriummalonsäureäthern zu den Aethern ungesättigter Säuren , 1887 .