Critical role of TLR7 in the acceleration of systemic lupus erythematosus in TLR9-deficient mice.
暂无分享,去创建一个
S. Akira | W. Reith | Tianfu Wu | Quanzhen Li | C. Mohan | S. Uematsu | I. Dunand-Sauthier | S. Izui | B. Kotzin | M. Santiago‐Raber
[1] I. Dunand-Sauthier,et al. Selective Up-Regulation of Intact, but Not Defective env RNAs of Endogenous Modified Polytropic Retrovirus by the Sgp3 Locus of Lupus-Prone Mice1 , 2009, The Journal of Immunology.
[2] Sandra D'Alfonso,et al. Kallikrein genes are associated with lupus and glomerular basement membrane-specific antibody-induced nephritis in mice and humans. , 2009, The Journal of clinical investigation.
[3] T. Moll,et al. Protection of Murine Systemic Lupus by the Ea Transgene without Expression of I-E Heterodimers1 , 2008, The Journal of Immunology.
[4] M. Gilliet,et al. Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases , 2008, Nature Reviews Immunology.
[5] S. Akira,et al. Evidence for Genes in Addition to Tlr7 in the Yaa Translocation Linked with Acceleration of Systemic Lupus Erythematosus1 , 2008, The Journal of Immunology.
[6] John E. Connolly,et al. Yaa autoimmune phenotypes are conferred by overexpression of TLR7 , 2008, European journal of immunology.
[7] R. Coffman,et al. Treatment of lupus‐prone mice with a dual inhibitor of TLR7 and TLR9 leads to reduction of autoantibody production and amelioration of disease symptoms , 2007, European journal of immunology.
[8] J. Ward,et al. Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. , 2007, Immunity.
[9] R. Coffman,et al. Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists , 2007, Nature Medicine.
[10] H. Ploegh,et al. The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling , 2007, The Journal of cell biology.
[11] Jianyong Wang,et al. The Functional Effects of Physical Interactions among Toll-like Receptors 7, 8, and 9* , 2006, Journal of Biological Chemistry.
[12] N. Olsen,et al. Protein array autoantibody profiles for insights into systemic lupus erythematosus and incomplete lupus syndromes , 2006, Clinical and experimental immunology.
[13] J. Shupe,et al. Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. , 2006, Immunity.
[14] S. Akira,et al. Toll-like receptor 7-dependent loss of B cell tolerance in pathogenic autoantibody knockin mice. , 2006, Immunity.
[15] T. Winkler,et al. Toll-like receptor 9-independent aggravation of glomerulonephritis in a novel model of SLE. , 2006, International immunology.
[16] P. Courville,et al. Role of TLR9 in Anti-Nucleosome and Anti-DNA Antibody Production in lpr Mutation-Induced Murine Lupus1 , 2006, The Journal of Immunology.
[17] Quanzhen Li,et al. A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[18] A. Satterthwaite,et al. Autoreactive B Cell Responses to RNA-Related Antigens Due to TLR7 Gene Duplication , 2006, Science.
[19] A. Aderem,et al. TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE , 2006, The Journal of Experimental Medicine.
[20] T. Moll,et al. Contribution of NZB Autoimmunity 2 to Y-Linked Autoimmune Acceleration-Induced Monocytosis in Association with Murine Systemic Lupus1 , 2006, The Journal of Immunology.
[21] S. Grinstein,et al. The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9 , 2006, Nature Immunology.
[22] Chandra Mohan,et al. Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays. , 2005, The Journal of clinical investigation.
[23] S. Akira,et al. RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement , 2005, The Journal of experimental medicine.
[24] S. Akira,et al. Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus , 2005, The Journal of experimental medicine.
[25] T. Moll,et al. Selective expansion of a monocyte subset expressing the CD11c dendritic cell marker in the Yaa model of systemic lupus erythematosus. , 2005, Arthritis and rheumatism.
[26] S. Akira,et al. Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus , 2005, The Journal of experimental medicine.
[27] S. Xiong,et al. Specific siRNA downregulated TLR9 and altered cytokine expression pattern in macrophage after CpG DNA stimulation. , 2005, Cellular & molecular immunology.
[28] T. Moll,et al. Differential Role of Three Major New Zealand Black-Derived Loci Linked with Yaa-Induced Murine Lupus Nephritis1 , 2005, The Journal of Immunology.
[29] S. Akira,et al. Toll-like receptors in innate immunity. , 2004, International immunology.
[30] D. Isenberg,et al. Is α-actinin a target for pathogenic anti-DNA antibodies in lupus nephritis? , 2004 .
[31] K. Tung,et al. Breaking Tolerance to Double Stranded DNA, Nucleosome, and Other Nuclear Antigens Is Not Required for the Pathogenesis of Lupus Glomerulonephritis , 2004, The Journal of experimental medicine.
[32] M. Shlomchik,et al. Activation of autoreactive B cells by CpG dsDNA. , 2003, Immunity.
[33] M. Wiznerowicz,et al. Conditional Suppression of Cellular Genes: Lentivirus Vector-Mediated Drug-Inducible RNA Interference , 2003, Journal of Virology.
[34] Steffen Jung,et al. Blood monocytes consist of two principal subsets with distinct migratory properties. , 2003, Immunity.
[35] M. Wener,et al. Multiple autoantibodies form the glomerular immune deposits in patients with systemic lupus erythematosus. , 2003, The Journal of rheumatology.
[36] M. Shlomchik,et al. Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors , 2002, Nature.
[37] C. Putterman,et al. α-Actinin Is a Cross-Reactive Renal Target for Pathogenic Anti-DNA Antibodies1 , 2002, The Journal of Immunology.
[38] S. Akira,et al. Small anti-viral compounds activate immune cells via the TLR7 MyD88–dependent signaling pathway , 2002, Nature Immunology.
[39] L. Rönnblom,et al. A Pivotal Role for the Natural Interferon α–producing Cells (Plasmacytoid Dendritic Cells) in the Pathogenesis of Lupus , 2001 .
[40] G. Peltz,et al. Evidence for an interferon-inducible gene, Ifi202, in the susceptibility to systemic lupus. , 2001, Immunity.
[41] M. Monestier,et al. Lupus anti‐DNA autoantibodies cross‐react with a glomerular structural protein: a case for tissue injury by molecular mimicry , 2001, European journal of immunology.
[42] S. Akira,et al. A Toll-like receptor recognizes bacterial DNA , 2000, Nature.
[43] D. Jarrossay,et al. Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon , 1999, Nature Medicine.
[44] B. Croker,et al. Genetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies. , 1999, The Journal of clinical investigation.
[45] N. Kadowaki,et al. The nature of the principal type 1 interferon-producing cells in human blood. , 1999, Science.
[46] G. Gilkeson,et al. Nephritogenic autoantibodies in lupus: current concepts and continuing controversies. , 1996, Arthritis and rheumatism.
[47] B. Kotzin. Systemic Lupus Erythematosus , 1996, Cell.
[48] S. Izui,et al. H‐2‐linked control of the Yaa gene‐induced acceleration of lupus‐like autoimmune disease in BXSB mice , 1992, European journal of immunology.
[49] M. Madaio,et al. A murine nephritogenic monoclonal anti‐DNA autoantibody binds directly to mouse laminin, the major non‐collagenous protein component of the glomerular basement membrane , 1989, European journal of immunology.
[50] S. Izui,et al. The Y chromosome from autoimmune BXSB/MpJ mice induces a lupus‐like syndrome in (NZW × C57BL/6)F1 male mice, but not in C57BL/6 male mice , 1988, European journal of immunology.
[51] P. Lambert,et al. Autoimmunity after induction of neonatal tolerance to alloantigens: role of B cell chimerism and F1 donor B cell activation. , 1986, Journal of immunology.
[52] L. van de Putte,et al. Cross-reactivity of human and murine anti-DNA antibodies with heparan sulfate. The major glycosaminoglycan in glomerular basement membranes. , 1986, The Journal of clinical investigation.
[53] W. Seaman,et al. Monocytosis in the BXSB model for systemic lupus erythematosus , 1984, Journal of Experimental Medicine.
[54] A. Theofilopoulos,et al. Association of circulating retroviral gp70-anti-gp70 immune complexes with murine systemic lupus erythematosus , 1979, The Journal of experimental medicine.
[55] A. Theofilopoulos,et al. Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains , 1978, The Journal of experimental medicine.
[56] J. August,et al. THE VIRAL ENVELOPE GLYCOPROTEIN OF MURINE LEUKEMIA VIRUS AND THE PATHOGENESIS OF IMMUNE COMPLEX GLOMERULONEPHRITIS OF NEW ZEALAND MICE , 1974, The Journal of experimental medicine.
[57] S. Peng,et al. Toll-like receptor 9 signaling protects against murine lupus. , 2006, Arthritis and rheumatism.
[58] B. Beutler,et al. TYPE I INTERFERONS (/) IN IMMUNITY AND AUTOIMMUNITY , 2005 .
[59] S. Akira,et al. A Novel Toll-Like Receptor that Recognizes Bacterial DNA , 2002 .