Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

[1]  Thomas Vierbuchen,et al.  Direct conversion of fibroblasts to functional neurons by defined factors , 2010, Nature.

[2]  T. Doetschman,et al.  Origin of Cardiac Fibroblasts and the Role of Periostin , 2009, Circulation research.

[3]  E. Marbán,et al.  Validation of the Cardiosphere Method to Culture Cardiac Progenitor Cells from Myocardial Tissue , 2009, PloS one.

[4]  T. Ichisaka,et al.  Suppression of induced pluripotent stem cell generation by the p53–p21 pathway , 2009, Nature.

[5]  S. Sheikh,et al.  Murine “Cardiospheres” Are Not a Source of Stem Cells with Cardiomyogenic Potential , 2009, Stem cells.

[6]  Benoit G. Bruneau,et al.  Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors , 2009, Nature.

[7]  Sean P. Palecek,et al.  Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells , 2009, Circulation research.

[8]  D. Srivastava,et al.  Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. , 2009, Developmental cell.

[9]  E. A. Packham,et al.  Physical Interaction between TBX5 and MEF2C Is Required for Early Heart Development , 2009, Molecular and Cellular Biology.

[10]  N. Chao Faculty Opinions recommendation of In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. , 2008 .

[11]  Douglas A. Melton,et al.  In vivo reprogramming of adult pancreatic exocrine cells to β-cells , 2008, Nature.

[12]  Benjamin J Bondow,et al.  Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice. , 2008, Developmental biology.

[13]  P. Doevendans,et al.  Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents. , 2008, Circulation research.

[14]  R. David,et al.  MesP1 drives vertebrate cardiovascular differentiation through Dkk-1-mediated blockade of Wnt-signalling , 2008, Nature Cell Biology.

[15]  Lila R Collins,et al.  Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts , 2007, Nature Biotechnology.

[16]  P. Couture,et al.  Thy-1 expression by cardiac fibroblasts: lack of association with myofibroblast contractile markers. , 2007, Journal of molecular and cellular cardiology.

[17]  K. Kimura,et al.  Sema3a maintains normal heart rhythm through sympathetic innervation patterning , 2007, Nature Medicine.

[18]  C. Ware,et al.  The FASEB Journal • Research Communication , 2007 .

[19]  Bing Li,et al.  The Role of Chromatin during Transcription , 2007, Cell.

[20]  S. Kattman,et al.  Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. , 2006, Developmental cell.

[21]  D. Srivastava,et al.  The paradoxical patent ductus arteriosus. , 2006, The Journal of clinical investigation.

[22]  D. Srivastava Making or Breaking the Heart: From Lineage Determination to Morphogenesis , 2006, Cell.

[23]  Thomas K Borg,et al.  Cardiac fibroblasts: friend or foe? , 2006, American journal of physiology. Heart and circulatory physiology.

[24]  S. Yamanaka,et al.  Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.

[25]  James A. Cuff,et al.  A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells , 2006, Cell.

[26]  David J. Miller,et al.  Gene Regulatory Networks in the Evolution and Development of the Heart , 2006 .

[27]  Karl-Ludwig Laugwitz,et al.  Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages , 2005, Nature.

[28]  T. Borg,et al.  Structural and functional characterisation of cardiac fibroblasts. , 2005, Cardiovascular research.

[29]  Gordon K Smyth,et al.  Statistical Applications in Genetics and Molecular Biology Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments , 2011 .

[30]  I. Rooman,et al.  In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells , 2004, Diabetologia.

[31]  T. Kitamura,et al.  Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics. , 2003, Experimental hematology.

[32]  D. Torella,et al.  Adult Cardiac Stem Cells Are Multipotent and Support Myocardial Regeneration , 2003, Cell.

[33]  Jonathan C. Cohen,et al.  GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5 , 2003, Nature.

[34]  Frank R. Lin,et al.  Opening of compacted chromatin by early developmental transcription factors HNF3 (FoxA) and GATA-4. , 2002, Molecular cell.

[35]  J. Schmitt,et al.  A Murine Model of Holt-Oram Syndrome Defines Roles of the T-Box Transcription Factor Tbx5 in Cardiogenesis and Disease , 2001, Cell.

[36]  Shankar Srinivas,et al.  Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus , 2001, BMC Developmental Biology.

[37]  J. Miyazaki,et al.  MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube. , 1999, Development.

[38]  C. Bucana,et al.  Control of mouse cardiac morphogenesis and myogenesis by transcription factor MEF2C. , 1997, Science.

[39]  J. Gulick,et al.  Isolation and characterization of the mouse cardiac myosin heavy chain genes. , 1991, The Journal of biological chemistry.

[40]  H. Weintraub,et al.  Expression of a single transfected cDNA converts fibroblasts to myoblasts , 1987, Cell.