Spectral analysis of photo-induced delayed luminescence from human skin in vivo

The UVA induced Delayed Luminescence (DL), has been measured in vivo in the forearm skin of some healthy volunteers of different sex and age during several periods of the year. An innovative instrument able to detect, in single photon counting mode, the spectrum and the time trend of the DL emission has been used. The measured differences in the time trends of the spectral components may be related to the sex and the age. The potential development of a new analysis technique based on this phenomenon is discussed.

[1]  H. Niggli,et al.  The cell nucleus of cultured melanoma cells as a source of ultraweak photon emission , 2005, Naturwissenschaften.

[2]  B. R. Masters,et al.  Optical Biopsy of In Vivo Human Skin: Multi-photon Excitation Microscopy , 1998, Lasers in Medical Science.

[3]  N Kollias,et al.  Aging and effects of ultraviolet A exposure may be quantified by fluorescence excitation spectroscopy in vivo. , 2001, The Journal of investigative dermatology.

[4]  Francesco Musumeci,et al.  Spectral analysis of laser-induced ultraweak delayed luminescence in cultured normal and tumor human cells: temperature dependence. , 2005, Journal of photochemistry and photobiology. B, Biology.

[5]  F A Popp,et al.  Biophoton emission of human body. , 1997, Indian journal of experimental biology.

[6]  Francesco Musumeci,et al.  Spectral analysis of Delayed Luminescence from human skin as a possible non-invasive diagnostic tool , 2007, European Biophysics Journal.

[7]  F. A. Popp,et al.  Delayed luminescence of biological systems in terms of coherent states , 2002 .

[8]  F. Musumeci,et al.  Photon emission from normal and tumor human tissues , 1992, Experientia.

[9]  F Musumeci,et al.  Delayed luminescence of biological systems arising from correlated many-soliton states. , 2001, Physical review. E, Statistical, nonlinear, and soft matter physics.

[10]  Francesco Musumeci,et al.  ‘Simultaneous’ measurements of delayed luminescence and chloroplast organization in Acetabularia acetabulum , 1999 .

[11]  Francesco Musumeci,et al.  Discrimination between normal and cancer cells by using spectral analysis of delayed luminescence. , 2005 .

[12]  Hans Christian Wulf,et al.  Autofluorescence spectrum of skin: component bands and body site variations , 2000, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[13]  W. Ruka,et al.  Fluorescence in situ detection of human cutaneous melanoma: study of diagnostic parameters of the method. , 2001, The Journal of investigative dermatology.

[14]  Terence Dwyer,et al.  Misclassification due to body hair and seasonal variation on melanin density estimates for skin type using spectrophotometry. , 2002, Journal of photochemistry and photobiology. B, Biology.