Discovery of potent, selective small molecule inhibitors of α-subtype of type III phosphatidylinositol-4-kinase (PI4KIIIα).
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M. Waring | D. M. Andrews | G. Robb | P. Raubo | M. Swarbrick | James M Smith | Jennifer C. McKelvie
[1] E. Bouřa,et al. Highly Selective Phosphatidylinositol 4-Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action. , 2015, Journal of medicinal chemistry.
[2] L. Hamann,et al. 2-Alkyloxazoles as potent and selective PI4KIIIβ inhibitors demonstrating inhibition of HCV replication. , 2014, Bioorganic & medicinal chemistry letters.
[3] M. Waring,et al. Potent, selective small molecule inhibitors of type III phosphatidylinositol-4-kinase α- but not β-inhibit the phosphatidylinositol signaling cascade and cancer cell proliferation. , 2014, Chemical Communications.
[4] C. Moore,et al. Discovery of selective small molecule type III phosphatidylinositol 4-kinase alpha (PI4KIIIα) inhibitors as anti hepatitis C (HCV) agents. , 2014, Journal of medicinal chemistry.
[5] L. Santambrogio,et al. The lipid kinase PI4KIIIβ preserves lysosomal identity , 2012, The EMBO journal.
[6] L. Delang,et al. The role of phosphatidylinositol 4-kinases and phosphatidylinositol 4-phosphate during viral replication , 2012, Biochemical Pharmacology.
[7] P. Raman,et al. Anti-Hepatitis C Virus Activity and Toxicity of Type III Phosphatidylinositol-4-Kinase Beta Inhibitors , 2012, Antimicrobial Agents and Chemotherapy.
[8] R. De Francesco,et al. Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity , 2012, PLoS pathogens.
[9] C. Burd,et al. Coordination of Golgi functions by phosphatidylinositol 4-kinases. , 2011, Trends in cell biology.
[10] G. Kukolj,et al. Identification of a lipid kinase as a host factor involved in hepatitis C virus RNA replication. , 2009, Virology.
[11] Pietro De Camilli,et al. Phosphoinositides in cell regulation and membrane dynamics , 2006, Nature.
[12] T. Balla,et al. Phosphatidylinositol 4-kinases: old enzymes with emerging functions. , 2006, Trends in cell biology.
[13] M. Roth. Phosphoinositides in constitutive membrane traffic. , 2004, Physiological reviews.