Entropy in the natural time domain.

A surrogate data analysis is presented, which is based on the fluctuations of the "entropy" S defined in the natural time domain [Phys. Rev. E 68, 031106 (2003)]]. This entropy is not a static one such as, for example, the Shannon entropy. The analysis is applied to three types of time series, i.e., seismic electric signals, "artificial" noises, and electrocardiograms, and it "recognizes" the non-Markovianity in all these signals. Furthermore, it differentiates the electrocardiograms of healthy humans from those of the sudden cardiac death ones. If deltaS and deltaSshuf denote the standard deviation when calculating the entropy by means of a time window sweeping through the original data and the "shuffled" (randomized) data, respectively, it seems that the ratio deltaSshuf /deltaS plays a key role. The physical meaning of deltaSshuf is investigated.

[1]  J. Rogers Chaos , 1876, Molecular Vibrations.

[2]  I. S. Gradshteyn,et al.  Table of Integrals, Series, and Products , 1976 .

[3]  Feller William,et al.  An Introduction To Probability Theory And Its Applications , 1950 .

[4]  Irene A. Stegun,et al.  Handbook of Mathematical Functions. , 1966 .

[5]  P Caminal,et al.  Automatic detection of wave boundaries in multilead ECG signals: validation with the CSE database. , 1994, Computers and biomedical research, an international journal.

[6]  H. Stanley,et al.  Quantification of scaling exponents and crossover phenomena in nonstationary heartbeat time series. , 1995, Chaos.

[7]  Steven J. Schiff,et al.  Tests for nonlinearity in short stationary time series. , 1995, Chaos.

[8]  Jeffrey M. Hausdorff,et al.  Physionet: Components of a New Research Resource for Complex Physiologic Signals". Circu-lation Vol , 2000 .

[9]  T. Schreiber,et al.  Surrogate time series , 1999, chao-dyn/9909037.

[10]  Teodor Buchner,et al.  Symbolic dynamics and complexity in a physiological time series , 2000 .

[11]  L. Glass Synchronization and rhythmic processes in physiology , 2001, Nature.

[12]  M. Ausloos,et al.  Application of dwell-time series in studies of long-range correlation in single channel ion transport: analysis of ion current through a big conductance locust potassium channel , 2001 .

[13]  Luís A. Nunes Amaral,et al.  From 1/f noise to multifractal cascades in heartbeat dynamics. , 2001, Chaos.

[14]  Dante R. Chialvo,et al.  Physiology: Unhealthy surprises , 2002, Nature.

[15]  I. Khan Long QT syndrome: diagnosis and management. , 2002, American heart journal.

[16]  Jeffrey M. Hausdorff,et al.  Fractal dynamics in physiology: Alterations with disease and aging , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[17]  P. Varotsos,et al.  Long-range correlations in the electric signals that precede rupture. , 2002, Physical review. E, Statistical, nonlinear, and soft matter physics.

[18]  P. Varotsos,et al.  Attempt to distinguish electric signals of a dichotomous nature. , 2003, Physical review. E, Statistical, nonlinear, and soft matter physics.

[19]  Patrick E. McSharry,et al.  A dynamical model for generating synthetic electrocardiogram signals , 2003, IEEE Transactions on Biomedical Engineering.

[20]  P. Varotsos,et al.  Long-range correlations in the electric signals that precede rupture: further investigations. , 2003, Physical review. E, Statistical, nonlinear, and soft matter physics.

[21]  P. Laguna,et al.  New algorithm for QT interval analysis in 24-hour Holter ECG: performance and applications , 2006, Medical and Biological Engineering and Computing.