Toward Automated Tissue Classification for Markerless Orthopaedic Robotic Assistance

A markerless computer aided orthopaedic platform will require a complex computer vision system to isolate and track rigid bodies used to localize a robot to a patient. Isolating rigid bodies such as bone requires accurate segmentation and this study explores using diffuse laser reflectivity to accurately classify tissue. Lasers (red at 650nm and infrared – IR – at 850nm) intersected four material types; cartilage, ligament, muscle and metal surgical tools within a controlled cadaveric setup. Images were captured with an infrared CMOS sensor, pre-processed to isolate laser centers, and resized to test information requirements. Images for both laser types were scaled from <inline-formula> <tex-math notation="LaTeX">$5\times5$ </tex-math></inline-formula> pixels to <inline-formula> <tex-math notation="LaTeX">$30\times30$ </tex-math></inline-formula> pixels and trained on a convolutional neural network, GoogLeNet. At sizes above <inline-formula> <tex-math notation="LaTeX">$15\times15$ </tex-math></inline-formula> pixels, the IR laser had a higher classification accuracy, reaching 97.8% at <inline-formula> <tex-math notation="LaTeX">$30\times30$ </tex-math></inline-formula> pixels, whereas the red laser peaked at 94.1%. It was shown as not possible to qualitatively identify materials that were not trained in the network based on their probability outputs. Further work will be performed to classify multiple points in a single scene as a step toward segmenting entire surgical views for markerless Computer Assisted Orthopedic Surgery (CAOS) systems.

[1]  Bram van Ginneken,et al.  A survey on deep learning in medical image analysis , 2017, Medical Image Anal..

[2]  Anna Hilsmann,et al.  Validation of two techniques for intraoperative hyperspectral human tissue determination , 2019, Medical Imaging.

[3]  Daniel Sierra-Sosa,et al.  Tissue classification and segmentation of pressure injuries using convolutional neural networks , 2018, Comput. Methods Programs Biomed..

[4]  Nassir Navab,et al.  Automatic bone detection and soft tissue aware ultrasound–CT registration for computer-aided orthopedic surgery , 2015, International Journal of Computer Assisted Radiology and Surgery.

[5]  Vivienne Sze,et al.  Hardware for machine learning: Challenges and opportunities , 2017, 2017 IEEE Custom Integrated Circuits Conference (CICC).

[6]  M. Hepinstall,et al.  Pin Site Complications Associated With Computer-Assisted Navigation in Hip and Knee Arthroplasty. , 2017, The Journal of arthroplasty.

[7]  Hesham A. Hefny,et al.  An enhanced deep learning approach for brain cancer MRI images classification using residual networks , 2020, Artif. Intell. Medicine.

[8]  Sylvie Treuillet,et al.  Hyperspectral interventional imaging for enhanced tissue visualization and discrimination combining band selection methods , 2016, International Journal of Computer Assisted Radiology and Surgery.

[9]  Dumitru Erhan,et al.  Going deeper with convolutions , 2014, 2015 IEEE Conference on Computer Vision and Pattern Recognition (CVPR).

[10]  Manuel Wiesenfarth,et al.  Classification of Cancer at Prostate MRI: Deep Learning versus Clinical PI-RADS Assessment. , 2019, Radiology.

[11]  Patrick van der Smagt,et al.  CNN-based Segmentation of Medical Imaging Data , 2017, ArXiv.

[12]  Langan S. Smith,et al.  Does Robotic-Assisted Total Hip Arthroplasty Improve Accuracy of Cup Positioning? , 2019, The Journal of Hip Surgery.

[13]  Anna Hilsmann,et al.  Intraoperative hyperspectral determination of human tissue properties , 2018, Journal of biomedical optics.

[14]  Nassir Navab,et al.  Multi-modal imaging, model-based tracking, and mixed reality visualisation for orthopaedic surgery , 2017, Healthcare technology letters.

[15]  D. Jacofsky,et al.  Robotic-Arm Assisted Total Knee Arthroplasty Demonstrated Greater Accuracy and Precision to Plan Compared with Manual Techniques , 2018, The Journal of Knee Surgery.

[16]  Jin Liu,et al.  Applications of deep learning to MRI images: A survey , 2018, Big Data Min. Anal..

[17]  P. Boisrenoult,et al.  Pin track induced fractures around computer-assisted TKA. , 2010, Orthopaedics & traumatology, surgery & research : OTSR.

[18]  N. Arunkumar,et al.  Optimal deep learning model for classification of lung cancer on CT images , 2019, Future Gener. Comput. Syst..

[19]  Valery V. Tuchin,et al.  OPTICAL PROPERTIES OF SKIN, SUBCUTANEOUS, AND MUSCLE TISSUES: A REVIEW , 2011 .

[20]  I. Holloway,et al.  A vascular complication in computer navigated total knee arthroplasty , 2013, Indian journal of orthopaedics.

[21]  Ritse Mann,et al.  Automated soft tissue lesion detection and segmentation in digital mammography using a u-net deep learning network , 2018, ArXiv.

[22]  M. Sheinkop,et al.  Femoral fracture through a previous pin site after computer-assisted total knee arthroplasty. , 2008, The Journal of arthroplasty.