论文信息 - Effect of inhomogeneities on the apparent location and magnitude of a cardiac current dipole source.

Effect of inhomogeneities on the apparent location and magnitude of a cardiac current dipole source.

A mathematical model was used to investigate the effects of electrical inhomogeneities introduced by the intracavitary blood mass and the lungs on the apparent location and magnitude of a current dipole source representing local activity in the myocardium. Radial and tangential current source moments were considered, and lung conductivity was taken as a variable parameter. Both the blood mass and the lungs cause a current source to appear closer to the heart center than it actually is. The effect increases as the source moves away from the endocardial surface, and maximum displacement is estimated to be of the order of 1 cm. The net effect of the inhomogeneities is to increase the magnitude of the radial component of a source dipole while diminishing its tangential component. These effects depend on source location.

R. M. Arthur | D. Geselowitz

[1] D. Brody. A Theoretical Analysis of Intracavitary Blood Mass Influence on the Heart‐Lead Relationship , 1956, Circulation research.

[2] D. B. Geselowitz,et al. Multipole Representation for an Equivalent Cardiac Generator , 1960, Proceedings of the IRE.

[3] John W. Evans,et al. A Theoretical Basis for Determining Heart-Lead Relationships of the Equivalent Cardiac Multipole , 1961 .

[4] D B Geselowitz,et al. Two theorems concerning the quadrupole applicable to electrocardiography. , 1965, IEEE transactions on bio-medical engineering.

[5] The human heart: some aspects of its excitation. , 1966, Transactions & studies of the College of Physicians of Philadelphia.

[6] S. Rush,et al. Qualitative effects of thoracic resistivity variations on the interpretation of electrocardiograms: the "Brody" effect. , 1967, American heart journal.

[7] D. Geselowitz. On bioelectric potentials in an inhomogeneous volume conductor. , 1967, Biophysical journal.

[8] D. Durrer. Electrical aspects of human cardiac activity: a clinical-physiological approach to excitation and stimulation. , 1968, Cardiovascular research.

[9] R W Schubert. An experimental study of the multipole series that represents the human electrocardiogram. , 1968, IEEE transactions on bio-medical engineering.