A simulated driving evaluation for patients with Alzheimer's disease

A prospective study concerning the driving ability of 41 patients with the diagnosis of Alzheimer's disease (AD) was performed. Using a simulated driving test we evaluated the predictive value of the MMSE,'4 ADL,5-7 and IADL&9 to determine the ability of a person with Alzheimer's disease to drive. All patients were driving at the time of the evaluation. There was no correlation between driving performance and functional status evaluated by ADL and IADL. When comparing driving performance with cognitive evaluation by MMSE, a significant number of patients with MMSE c 22failed the test, compared to patients with MMSE > 22 (P = 0.01, Fisher's exact test). No patient with a MMSE < 20 passed the driving test. The authors recommend that health care professionals who are caring for people with Alzheimer's disease with a MMSE of22 or less should request a driving evaluation.

[1]  Sydney Katz Assessing Self‐maintenance: Activities of Daily Living, Mobility, and Instrumental Activities of Daily Living , 1983, Journal of the American Geriatrics Society.

[2]  C. Miller,et al.  Optic-nerve degeneration in Alzheimer's disease. , 1986, The New England journal of medicine.

[3]  N. Mayo,et al.  Determining medical fitness to drive: physicians' responsibilities in Canada. , 1989, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[4]  J. A. Waller Chronic medical conditions and traffic safety: review of the California experience. , 1965, The New England journal of medicine.

[5]  D. Drachman,et al.  Driving and Alzheimer's disease , 1993, Neurology.

[6]  H. Karlinsky,et al.  The Impact of Alzheimer's Disease on Driving Ability: A Review , 1990, Journal of geriatric psychiatry and neurology.

[7]  M P Lawton,et al.  A research and service oriented multilevel assessment instrument. , 1982, Journal of gerontology.

[8]  Mario Liotti,et al.  Visuoimaginal constructional apraxia: On a case of selective deficit of imagery , 1986, Brain and Cognition.

[9]  M P Lawton,et al.  Scales to measure competence in everyday activities. , 1988, Psychopharmacology bulletin.

[10]  A R Damasio,et al.  Preserved motor learning in Alzheimer's disease: implications for anatomy and behavior , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[11]  D. Kay,et al.  Dementia and depression among the elderly living in the Hobart community: the effect of the diagnostic criteria on the prevalence rates , 1985, Psychological Medicine.

[12]  N. Pachana,et al.  Alzheimer and vascular dementias and driving. A prospective road and laboratory study. , 1995, JAMA.

[13]  J Marshall,et al.  Cerebral blood flow in dementia. , 1975, Archives of neurology.

[14]  M. Folstein,et al.  The Mini-Mental State Examination. , 1983, Archives of general psychiatry.

[15]  J. Haxby,et al.  Motor vehicle crashes in dementia of the alzheimer type , 1988, Annals of neurology.

[16]  B. Reisberg,et al.  The Global Deterioration Scale for assessment of primary degenerative dementia. , 1982, The American journal of psychiatry.

[17]  M. Folstein,et al.  Limits of the ‘Mini-Mental State’ as a screening test for dementia and delirium among hospital patients , 1982, Psychological Medicine.

[18]  S. Folstein,et al.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.

[19]  S. Weintraub,et al.  To Drive or Not To Drive: Preliminary Results From Road Testing of Patients With Dementia , 1992, Journal of geriatric psychiatry and neurology.

[20]  R. Steffes,et al.  Visual Field Limitation in the Patient with Dementia of the Alzheimer's Type , 1987, Journal of the American Geriatrics Society.

[21]  J L Graca,et al.  Driving and aging. , 1986, Clinics in geriatric medicine.

[22]  J. Morris,et al.  Driving Performance in Persons with Mild Senile Dementia of the Alzheimer Type , 1993, Journal of the American Geriatrics Society.

[23]  J. Morley,et al.  Attitudes of Physicians toward Elderly Drivers and Driving Policy , 1993, Journal of the American Geriatrics Society.

[24]  D. Carr,et al.  The Effect of Age on Driving Skills , 1992, Journal of the American Geriatrics Society.

[25]  L. Tune,et al.  Driving in Patients with Dementia , 1988, Journal of the American Geriatrics Society.

[26]  O. L. Zangwill,et al.  VISUAL-CONSTRUCTIVE DISABILITIES ASSOCIATED WITH LESIONS OF THE LEFT CEREBRAL HEMISPHERE , 1960 .

[27]  D B Reuben,et al.  The Aging Driver Medicine, Policy, and Ethics , 1988, Journal of the American Geriatrics Society.

[28]  WHICH COGNITIVELY IMPAIRED PATIENTS CAN DRIVE SAFELY , 1995 .

[29]  M. Folstein,et al.  Clinical diagnosis of Alzheimer's disease , 1984, Neurology.

[30]  M. Folstein,et al.  The Meaning of Cognitive Impairment in the Elderly , 1985, Journal of the American Geriatrics Society.

[31]  R. Katzman.,et al.  Validation of a short Orientation-Memory-Concentration Test of cognitive impairment. , 1983, The American journal of psychiatry.

[32]  E. Renzi,et al.  The Relationship Between Visuo-Spatial Impairment and Constructional Apraxia , 1967 .

[33]  F. Buonanno,et al.  Spatial vision in Alzheimer's disease. General findings and a case report. , 1985, Archives of neurology.

[34]  Klaus P. Ebmeier,et al.  Dementia in idiopathic Parkinson's disease: prevalence and relationship with symptoms and signs of Parkinsonism , 1991, Psychological Medicine.

[35]  G. Adler,et al.  Driving and dementia: perspectives from an outpatient clinic. , 1992, Social work in health care.

[36]  S. Retchin,et al.  An overview of the older driver. , 1993, Clinics in geriatric medicine.

[37]  D. Persson,et al.  The elderly driver: deciding when to stop. , 1993, The gerontologist.

[38]  R. Phillips Primary Care Geriatrics , 1984 .

[39]  J. Morris,et al.  Validation of clinical diagnostic criteria for Alzheimer's disease , 1988, Annals of neurology.

[40]  S. Katz,et al.  A Measure of Primary Sociobiological Functions , 1976, International journal of health services : planning, administration, evaluation.

[41]  D. Bennett,et al.  Cessation of driving and unsafe motor vehicle operation by dementia patients. , 1991, Archives of internal medicine.

[42]  K. Ball,et al.  Visual/cognitive correlates of vehicle accidents in older drivers. , 1991, Psychology and aging.

[43]  M. Roth,et al.  The Association Between Quantitative Measures of Dementia and of Senile Change in the Cerebral Grey Matter of Elderly Subjects , 1968, British Journal of Psychiatry.

[44]  D. Drachman,et al.  Who may drive? Who may not? Who shall decemberide? , 1988, Annals of neurology.

[45]  R. Dubinsky,et al.  Driving in Alzheimer's Disease , 1992, Journal of the American Geriatrics Society.

[46]  S. Katz,et al.  Progress in development of the index of ADL. , 1970, The Gerontologist.

[47]  Alex Martin,et al.  Differential perceptual-spatial impairment in Huntington's and Alzheimer's dementias. , 1984, Archives of neurology.

[48]  D. Carr,et al.  Assessing older drivers for physical and cognitive impairment. , 1993, Geriatrics.

[49]  M. Tinetti,et al.  Predictors of Automobile Crashes and Moving Violations among Elderly Drivers , 1994, Annals of Internal Medicine.

[50]  C. P. Hughes,et al.  Mild senile dementia of Alzheimer type: research diagnostic criteria, recruitment, and description of a study population. , 1982, Journal of neurology, neurosurgery, and psychiatry.

[51]  J. Morris Differential diagnosis of Alzheimer's disease. , 1994, Clinics in geriatric medicine.

[52]  V. Giannetti Dementia and depression among the elderly. , 1983, American pharmacy.