Towards an applied multicriteria model to the diagnosis of Alzheimer's disease: A neuroimaging study case

The Alzheimer's disease has become the most frequent cause of dementia in the last few years, and it is responsible, alone or in association with other diseases, for 50% of the cases in western countries. The main focus of this work is to develop a multicriteria model for aiding in decision making on the diagnosis of Alzheimer's disease by using the Aranau Tool, structured on the Verbal Decision Analysis. In this work, the modeling and evaluation processes were conducted with the aid of a medical expert, bibliographic sources and questionnaires. The questionnaires taken into account were based mainly on patients' neuroimaging tests, and we analyzed wheter or not there were problems in the patients' brain that could be relevant to the diagnosis of Alzheimer's disease.

[1]  Omar Abou Khaled,et al.  Interweaving knowledge management, argumentation and decision making in a collaborative setting: the KAD ontology model , 2005, Int. J. Knowl. Learn..

[2]  R. Mohs,et al.  Consortium to establish a registry for Alzheimer's disease (CERAD) clinical and neuropsychological assessment of Alzheimer's disease. , 2002, Psychopharmacology bulletin.

[3]  C. P. Hughes,et al.  A New Clinical Scale for the Staging of Dementia , 1982, British Journal of Psychiatry.

[4]  Oleg I. Larichev,et al.  Verbal Decision Analysis for Unstructured Problems , 1997 .

[5]  S. Bassett Attention: Neuropsychological Predictor of Competency in Alzheimer's Disease , 1999, Journal of geriatric psychiatry and neurology.

[6]  W. Sturm,et al.  Neuropsychological assessment , 2007, Journal of Neurology.

[7]  R. Bartha,et al.  Ventricular enlargement as a possible measure of Alzheimer's disease progression validated using the Alzheimer's disease neuroimaging initiative database. , 2008, Brain : a journal of neurology.

[8]  Dmitry Kochin,et al.  VERBAL DECISION ANALYSIS METHODS FOR DETERMINING THE EFFICIENCY OF INVESTMENTS IN CONSTRUCTION , 2004 .

[9]  Plácido Rogério Pinheiro,et al.  A co-evolutionary interaction design of digital TV applications based on verbal decision analysis of user experiences , 2009 .

[10]  M. Prince,et al.  Predicting the onset of Alzheimer's disease using Bayes' theorem. , 1996, American journal of epidemiology.

[11]  Oleg I. Larichev,et al.  Method ZAPROS for Multicriteria Alternatives Ranking and the Problem of Incomparability , 2001, Informatica.

[12]  Plácido Rogério Pinheiro,et al.  Challenging the Incomparability Problem: An Approach Methodology Based on ZAPROS , 2008, MCO.

[13]  David L. Olson,et al.  Ordinal judgments in multiattribute decision analysis , 2002, Eur. J. Oper. Res..

[14]  Oleg I. Larichev,et al.  Ranking multicriteria alternatives: The method ZAPROS III , 2001, Eur. J. Oper. Res..

[15]  Plácido Rogério Pinheiro,et al.  A Co-evolutionary Interaction Design of Digital TV Applications Based on Verbal Decision Analysis of User Experiences , 2008, WSKS.

[16]  Gerald van Belle,et al.  Consortium to Establish a Registry for Alzheimer’s Disease (CERAD): The first twenty years , 2008, Alzheimer's & Dementia.

[17]  C Baskerville,et al.  THE TITLES OF PAPERS. , 1904, Science.

[18]  J. Morris,et al.  The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assesment of Alzheimer's disease , 1989, Neurology.