论文信息 - An automatic, on-line glucose analyzer for feed-back control of fed-batch growth of Escherichia coli

An automatic, on-line glucose analyzer for feed-back control of fed-batch growth of Escherichia coli

A computer-assisted on-line glucose analyzer was developed for feed-back control of cell growth. Using this system the glucose consumption rate for Escherichia coli was determined to be linear during batch culture at 0.37 g/hr. On-line feed-back control of glucose concentration at 1.5±0.5 g/L was used with fed-batch cultures to produce 31.2 g dry weight of E. coli cells/L in 12 h.

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