Central projections of the brachial nerve in bullfrogs: Muscle and cutaneous afferents project to different regions of the spinal cord

The central projections of muscle and cutaneous sensory neurons in the bullfrog were labeled by filling their peripheral axons in the forelimb with horseradish peroxidase (HRP). Muscle afferent fibers were found to project exclusively to the ventral neuropil of the brachial spinal cord in the intermediate gray zone. Cutaneous afferent axons had their arbors limited to the dorsal neuropil. There is therefore a topography in the central representation of two classes of sensory modalities.

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