Comprehensive mutation detection of BRCA1/2 genes reveals large genomic rearrangements contribute to hereditary breast and ovarian cancer in Chinese women

[1]  R. Ling,et al.  Germline mutations in 40 cancer susceptibility genes among Chinese patients with high hereditary risk breast cancer , 2018, International journal of cancer.

[2]  Yuntao Xie,et al.  Germline Mutations in Cancer Susceptibility Genes in a Large Series of Unselected Breast Cancer Patients , 2017, Clinical Cancer Research.

[3]  Xin Hu,et al.  The spectrum of BRCA mutations and characteristics of BRCA‐associated breast cancers in China: Screening of 2,991 patients and 1,043 controls by next‐generation sequencing , 2017, International journal of cancer.

[4]  A. Jemal,et al.  Cancer statistics in China, 2015 , 2016, CA: a cancer journal for clinicians.

[5]  Xiaojia Wang,et al.  Novel germline mutations and unclassified variants of BRCA1 and BRCA2 genes in Chinese women with familial breast/ovarian cancer , 2016, BMC Cancer.

[6]  T. Chan,et al.  The importance of analysis of long-range rearrangement of BRCA1 and BRCA2 in genetic diagnosis of familial breast cancer. , 2015, Cancer genetics.

[7]  Yuntao Xie,et al.  Mutations in RECQL Gene Are Associated with Predisposition to Breast Cancer , 2015, PLoS genetics.

[8]  Bale,et al.  Standards and Guidelines for the Interpretation of Sequence Variants: A Joint Consensus Recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology , 2015, Genetics in Medicine.

[9]  Sung-Won Kim,et al.  A multi-institutional study of the prevalence of BRCA1 and BRCA2 large genomic rearrangements in familial breast cancer patients , 2014, BMC Cancer.

[10]  G. Scambia,et al.  Advanced tools for BRCA1/2 mutational screening: comparison between two methods for large genomic rearrangements (LGRs) detection , 2014, Clinical chemistry and laboratory medicine.

[11]  Wanqing Chen,et al.  Breast cancer in China. , 2014, The Lancet. Oncology.

[12]  Jicheng Li,et al.  Hereditary Breast Cancer in the Han Chinese Population , 2013, Journal of epidemiology.

[13]  J. Benítez,et al.  Characterization of four novel BRCA2 large genomic rearrangements in Spanish breast/ovarian cancer families: review of the literature, and reevaluation of the genetic mechanisms involved in their origin , 2012, Breast Cancer Research and Treatment.

[14]  Yuntao Xie,et al.  RAD51C germline mutations in Chinese women with familial breast cancer , 2011, Breast Cancer Research and Treatment.

[15]  K. Offit,et al.  Absence of genomic BRCA1 and BRCA2 rearrangements in Ashkenazi breast and ovarian cancer families , 2010, Breast Cancer Research and Treatment.

[16]  Roberto Giugliani,et al.  Genomic rearrangements in BRCA1 and BRCA2: A literature review , 2009, Genetics and molecular biology.

[17]  Anders Albrechtsen,et al.  Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovarian cancer families , 2009, Breast Cancer Research and Treatment.

[18]  T. Rebbeck,et al.  The relative contribution of point mutations and genomic rearrangements in BRCA1 and BRCA2 in high-risk breast cancer families. , 2008, Cancer research.

[19]  J. Sng,et al.  Identification of novel BRCA large genomic rearrangements in Singapore Asian breast and ovarian patients with cancer , 2007, Clinical genetics.

[20]  T. Walsh,et al.  Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer. , 2006, JAMA.

[21]  M. Hjelm,et al.  Prevalence of mutations in the BRCA1 gene among Chinese patients with breast cancer. , 1999, Journal of the National Cancer Institute.

[22]  G. Lenoir,et al.  A 1-kb Alu-mediated germ-line deletion removing BRCA1 exon 17. , 1997, Cancer research.

[23]  Jianjun Liu,et al.  Large BRCA1 and BRCA2 genomic rearrangements in Malaysian high risk breast-ovarian cancer families , 2010, Breast Cancer Research and Treatment.

[24]  E. V. Rensburg,et al.  Large genomic rearrangements of the BRCA1 and BRCA2 genes: review of the literature and report of a novel BRCA1 mutation , 2010, Breast Cancer Research and Treatment.